Journal
INTERNATIONAL JOURNAL OF CARDIOLOGY
Volume 205, Issue -, Pages 117-123Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijcard.2015.12.006
Keywords
Takayasu arteritis; Renal artery stenosis; Stent placement; Angioplasty; Clinical outcome; Hypertension
Categories
Ask authors/readers for more resources
Objectives We aimed to investigate the long-term clinical outcomes of selective stenting versus percutaneous balloon angioplasty (PTA) in hypertensive patients with renal artery stenosis caused by Takayasu arteritis (RASTA). Methods We retrospectively analyzed the data of consecutive 152 RASTA patients from Fuwai Hospital between 2005 and 2012. All target lesions of renal arteries were firstly treated by plain PTA. After angioplasty, if flow-limited dissection and/or residual stenosis >50% of diameter on angiogram existed, a selective stenting was then followed to further morphological improvement. Results The baseline characteristics between PTA (n = 93) and stenting groups (n = 59) were indistinguishable. At two-year follow-up, the rates of normalized, improved, and unaltered hypertension were 27.4%, 63.4% and 12.3% in PTA group (n = 93) versus 22.4%, 62.1% and 15.5% respectively in stenting group (p = 0.79). Primary patency rate was 90.1% in renal arteries (125 lesions) treated with PTA versus 75.6% in renal arteries (64 lesions) treated with stent placement (p = 0.008). Female, active stage of the disease requiring glucocorticoid and/or immunosuppressant agents, residual stenosis rate and stenting were significantly associated with the restenosis. In patients with restenosis, renal artery occlusion occurred more in stenting group (8/15), compared with that in PTA group (1/12) (p = 0.019). The stenting group underwent more reintervention procedures than PTA group (13/63 versus 8/125, p = 0.003). Conclusions If PTA alone failed in treating RASTA, selective stenting resulted in similarly effective blood pressure reduction. Stenting also resulted in lower 2-year primary patency rate, higher occlusion rate and higher reintervention rate than those who did not need stenting. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available