Phytosynthesis of silver nanoparticles from Jatropha integerrima Jacq. flower extract and their possible applications as antibacterial and antioxidant agent

Jatropha integerrima Jacq. flower extract was used for the synthesis of silver nanoparticles in the current study. Various spectroscopic analyses were used to characterize the synthesized nanoparticles (JIF-AgNPs). The antibacterial efficacy of JIF-AgNPs was studied by well diffusion and microdilution techniques. In addition, the impact of JIF-AgNPs on free radicals was evaluated. On the ultraviolet-visible spectrum, the nanoparticles exhibit the highest absorbance at 422 nm. Based on the Fourier transform infrared spectrum, phenols and amino acids were involved in capping the JIF-AgNPs. Crystalline sphere-shaped nanoparticles with an average size of 50.07 nm and zeta potential of -19.0 mV were confirmed by X-ray diffraction, transmission electron microscopy, and dynamic light scattering analysis respectively. The JIF-AgNPs exhibit the highest and lowest growth inhibitory activity towards E. coll. and B. subtilis. The minimal inhibitory concentration of JIF-AgNPs against E. coll., K. pneumoniae, S. aureus, and B. subtilis were 2.5, 5.0, 5.0, and 7.5 mu g/mL, respectively. The JIF-AgNPs exhibited significant radical scavenging activities against DPPH (IC50-32.5 +/- 0.06 mu g/mL), hydroxyl (IC50-25 +/- 0.09 mu g/mL), Superoxide (IC50-42.5 +/- 0.13 mu g/mL), and ABTs (IC50-33.5 +/- 0.15 mu g/mL). Thus, synthesized nanoparticles were a good alternative to develop an antibacterial and antioxidant agent. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.

Automated summary

In this study, silver nanoparticles were synthesized using Jatropha integerrima Jacq. flower extract and characterized through various spectroscopic analyses. The nanoparticles exhibited high inhibitory activity against various bacteria and significant radical scavenging activities, making them a promising option as antibacterial and antioxidant agents.