☆ 4.6 Article

Kaposi's Sarcoma-Associated Herpesvirus, but Not Epstein-Barr Virus, Co-infection Associates With Coronavirus Disease 2019 Severity and Outcome in South African Patients

FRONTIERS IN MICROBIOLOGY (2022)

Related references

Note: Only part of the references are listed.

Review Virology

The cytokine storm and COVID-19

Biying Hu et al.

Summary: COVID-19, caused by SARS-CoV-2, has become a global pandemic since its emergence in Wuhan, China, in December 2019, posing a serious threat to public health. Close contact and respiratory droplets are the main modes of transmission. The cytokine storm is closely associated with disease severity and mortality, emphasizing the importance of studying and treating the cytokine storm in COVID-19.

JOURNAL OF MEDICAL VIROLOGY (2021)

Add to Collection

Article Immunology

Risk Factors for Coronavirus Disease 2019 (COVID-19) Death in a Population Cohort Study from the Western Cape Province, South Africa

Andrew Boulle et al.

Summary: In South Africa, living with HIV and having current tuberculosis were independently associated with increased COVID-19 mortality. These findings highlight the impact of these two diseases on COVID-19 risk and demonstrate the associations between age, sex, and other comorbidities with COVID-19 mortality.

CLINICAL INFECTIOUS DISEASES (2021)

Add to Collection

Article Biology

SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus

Jungang Chen et al.

Summary: The study reveals that SARS-CoV-2 encoded proteins and some anti-COVID-19 drugs can induce lytic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV), increasing the risk of virus-associated cancers for KSHV-positive patients exposed to COVID-19 or undergoing its treatment, even after they have fully recovered from COVID-19.

COMMUNICATIONS BIOLOGY (2021)

Add to Collection

Article Infectious Diseases

EBV DNA increase in COVID-19 patients with impaired lymphocyte subpopulation count

Stefania Paolucci et al.

Summary: This study monitored the immunologic profile and opportunistic viral DNA increase in Italian patients with COVID-19 to identify markers of disease severity. It found a correlation between reduced CD8(+) T cells and NK counts, elevated EBV DNA levels, and COVID-19 severity, highlighting the importance of further evaluating the relationship between EBV load and disease severity in longitudinal studies.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Article Immunology

COVID-19 evolution during the pandemic – Implications of new SARS-CoV-2 variants on disease control and public health policies

Cock van Oosterhout et al.

Virulence (2021)

Add to Collection

News Item Multidisciplinary Sciences

The coronavirus is here to stay - here's what that means

Nicky Phillips

Summary: Scientists expect the virus that causes COVID-19 to become endemic and pose less danger over time, according to a Nature survey.

NATURE (2021)

Add to Collection

Article Virology

Epstein-Barr Virus Lytic Replication Induces ACE2 Expression and Enhances SARS-CoV-2 Pseudotyped Virus Entry in Epithelial Cells

Dinesh Verma et al.

Summary: Understanding the factors that affect the infectivity of SARS-CoV-2 is crucial in combating COVID-19. This study showed that Epstein-Barr virus (EBV) infection induced ACE2 expression in epithelial cells, increasing susceptibility to SARS-CoV-2. The EBV transcriptional activator Zta directly activated the ACE2 promoter, and inhibiting EBV replication may reduce susceptibility to SARS-CoV-2.

JOURNAL OF VIROLOGY (2021)

Add to Collection

Article Multidisciplinary Sciences

Positive Epstein-Barr virus detection in coronavirus disease 2019 (COVID-19) patients

Ting Chen et al.

Summary: This study revealed a high incidence of EBV coinfection in COVID-19 patients. Coinfection with EBV and SARS-CoV-2 was associated with fever and increased inflammation, indicating a potentially more severe condition.

SCIENTIFIC REPORTS (2021)

Add to Collection

Article Microbiology

Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation

Jeffrey E. Gold et al.

Summary: The study found a prevalence of 30.3% for long COVID symptoms among COVID-19 patients, with some initially asymptomatic patients developing long-term symptoms. Additionally, a significantly higher rate of EBV reactivation was observed in long COVID subjects compared to control subjects, suggesting a potential association between COVID-19 inflammation and EBV reactivation.

PATHOGENS (2021)

Add to Collection

Article Infectious Diseases

Herpesvirus reactivation during severe COVID-19 and high rate of immune defect

A. Saade et al.

Summary: The study found that the incidence of herpesvirus reactivation in patients treated in the ICU for severe COVID-19 was high, but in most cases did not require antiviral treatment. Pre-existing hematological malignancy and solid organ transplantation were independently associated with viral reactivation, but viral reactivation was not associated with mortality.

INFECTIOUS DISEASES NOW (2021)

Add to Collection

Article Medicine, Research & Experimental

Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection

Catherine Riou et al.

Summary: This study found that the attributes of SARS-CoV-2-specific CD4(+) T cells were associated with the severity of COVID-19, with severe cases showing poor polyfunctional potential, reduced proliferation capacity, and enhanced HLA-DR expression. HIV-1 and TB coinfection can alter the SARS-CoV-2 T cell response, with HIV-1 causing CD4(+) T cell depletion and active TB leading to decreased polyfunctional capacity of SARS-CoV-2-specific CD4(+) T cells in COVID-19 patients. Moreover, COVID-19 patients displayed a reduced frequency of Mycobacterium tuberculosis-specific CD4(+) T cells, which may affect TB disease progression.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Add to Collection

Article Infectious Diseases

High incidence of Epstein-Barr virus, cytomegalovirus, and human-herpes virus-6 reactivations in critically ill patients with COVID-19

A. Simonnet et al.

Summary: Critically ill patients with COVID-19 in the ICU are prone to herpesvirus reactivation, particularly with EBV, which occurs early and is associated with longer ICU stays.

INFECTIOUS DISEASES NOW (2021)

Add to Collection

Editorial Material Infectious Diseases

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China

David S. Hui et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Add to Collection

Article Immunology

The Contribution of Kaposi's Sarcoma-Associated Herpesvirus to Mortality in Hospitalized Human Immunodeficiency Virus-Infected Patients Being Investigated for Tuberculosis in South Africa

Melissa J. Blumenthal et al.

JOURNAL OF INFECTIOUS DISEASES (2019)

Add to Collection

Article Oncology

Mutual detection of Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus in blood and saliva of Cameroonians with and without Kaposi's sarcoma

Nazzarena Labo et al.

INTERNATIONAL JOURNAL OF CANCER (2019)

Add to Collection

Article Oncology

EPHA2 sequence variants are associated with susceptibility to Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma prevalence in HIV-infected patients

Melissa J. Blumenthal et al.

CANCER EPIDEMIOLOGY (2018)

Add to Collection

Review Virology

Interaction of Human Tumor Viruses with Host Cell Surface Receptors and Cell Entry

Georgia Schaefer et al.

VIRUSES-BASEL (2015)

Add to Collection

Article Multidisciplinary Sciences

High Seroprevalence of Human Herpesviruses in HIV-Infected Individuals Attending Primary Healthcare Facilities in Rural South Africa

Erik Schaftenaar et al.

PLOS ONE (2014)

Add to Collection

Review Microbiology

Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: rnulticentric Castleman disease (KSHV-MCD) and the KSHV inflammatory cytokine syndrome

Mark N. Polizzotto et al.

FRONTIERS IN MICROBIOLOGY (2012)

Add to Collection

Article Immunology

An Interleukin-6-Related Systemic Inflammatory Syndrome in Patients Co-Infected with Kaposi Sarcoma-Associated Herpesvirus and HIV but without Multicentric Castleman Disease

Thomas S. Uldrick et al.

CLINICAL INFECTIOUS DISEASES (2010)

Add to Collection

Article Biochemical Research Methods

Detection of antibodies to Kaposi's sarcoma-associated herpesvirus: A new approach using K8.1 ELISA and a newly developed recombinant LANA ELISA

Georgina L. Mbisa et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2010)

Add to Collection

Review Oncology

Kaposi's sarcoma and its associated herpesvirus

Enrique A. Mesri et al.

NATURE REVIEWS CANCER (2010)

Add to Collection

Article Computer Science, Interdisciplinary Applications

Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support

Paul A. Harris et al.

JOURNAL OF BIOMEDICAL INFORMATICS (2009)

Add to Collection

Article Immunology

Geographic Variation in the Prevalence of Kaposi Sarcoma-Associated Herpesvirus and Risk Factors for Transmission

Silvia de Sanjose et al.

JOURNAL OF INFECTIOUS DISEASES (2009)

Add to Collection

Review Oncology

Epstein-Barr virus and cancer

MP Thompson et al.

CLINICAL CANCER RESEARCH (2004)

Add to Collection

Article Oncology

Prevalence of Kaposi's sarcoma-associated herpesvirus infection in sex workers and women from the general population in Spain

S De Sanjose et al.

INTERNATIONAL JOURNAL OF CANCER (2002)

Add to Collection

© Peeref 2019-2024. All rights reserved.