4.6 Article

Meclizine Inhibits Pseudorabies Virus Replication by Interfering With Virus Entry and Release

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs

Dharma Rao Tompa et al.

Summary: Infections caused by microscopic viruses can lead to chronic illnesses like HIV/AIDS, flu, etc. Developing new and superior antiviral drugs is crucial, but the drugs can be toxic to human cells and viruses can develop resistance. Combination drugs targeting viral replication are common, but innovative strategies are needed to combat emerging viruses like Ebola and coronaviruses.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Veterinary Sciences

Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy

Yuxiao Xing et al.

Summary: The study showed that PGPSt can reduce PRV replication and inhibit PRV-induced autophagy. Additionally, PGPSt inhibits PRV replication by restoring the Akt/mTOR signaling pathway suppressed by PRV infection. These findings provide insights for the development of antiviral drugs.

RESEARCH IN VETERINARY SCIENCE (2021)

Review Virology

Current Status and Challenge of Pseudorabies Virus Infection in China

Lei Tan et al.

Summary: PR, a highly infectious disease caused by PRV, has been prevalent in Chinese pig industry, posing significant economic losses. Despite efforts in diagnostic approaches and vaccine development, PR remains a major concern in the swine industry in China.

VIROLOGICA SINICA (2021)

Article Virology

Whole-Genome Sequence Analysis of Pseudorabies Virus Clinical Isolates from Pigs in China between 2012 and 2017 in China

Ruiming Hu et al.

Summary: The genomes of novel PRV variants isolated in China from 2012 to 2017 show high relatedness and genetic similarity to classic China strains. Recombination events play a significant role in viral evolution, while most genes are under evolutionary constraint. Positive selection affects 19 amino acid residue sites in 15 genes, leading to the identification of 37 unique mutations distinguishing the novel variants from classic strains.

VIRUSES-BASEL (2021)

Review Immunology

A review: Mechanism of action of antiviral drugs

Shamaila Kausar et al.

Summary: Antiviral drugs are a class of medicines used to treat viral infections, with strategies focusing on targeting the viruses themselves or host cell factors. Viruses can cause various serious diseases in humans, animals, and plants, and the action mechanism of antiviral drugs includes inhibiting viral nucleic acid synthesis and enhancing cell resistance to viruses.

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2021)

Article Microbiology

Hydroquinone inhibits PRV infection in neurons in vitro and in vivo

Linlin Fang et al.

VETERINARY MICROBIOLOGY (2020)

Article Virology

Virus Impact on Lipids and Membranes

Ellen Ketter et al.

ANNUAL REVIEW OF VIROLOGY, VOL 6, 2019 (2019)

Article Infectious Diseases

Characteristics of human encephalitis caused by pseudorabies virus: A case series study

Xue Yang et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2019)

Editorial Material Immunology

Pseudorabies virus: a neglected zoonotic pathogen in humans?

Gary Wong et al.

EMERGING MICROBES & INFECTIONS (2019)

Article Microbiology

Vaccines against pseudorabies virus (PrV)

C. M. Freuling et al.

VETERINARY MICROBIOLOGY (2017)

Review Microbiology

Control of swine pseudorabies in China: Opportunities and limitations

Yuan Sun et al.

VETERINARY MICROBIOLOGY (2016)

Article Microbiology

Emergence of a Pseudorabies virus variant with increased virulence to piglets

Wu Tong et al.

VETERINARY MICROBIOLOGY (2015)

Article Biochemistry & Molecular Biology

Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells

Daisuke Hishikawa et al.

JOURNAL OF LIPID RESEARCH (2014)

Review Biochemistry & Molecular Biology

Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells

Jean E. Vance et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

Review Biochemistry & Molecular Biology

Regulation of Phosphatidylethanolamine Homeostasis-The Critical Role of CTP: Phosphoethanolamine Cytidylyltransferase (Pcyt2)

Zvezdan Pavlovic et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Biochemistry & Molecular Biology

Meclizine Inhibits Mitochondria! Respiration through Direct Targeting of Cytosolic Phosphoethanolamine Metabolism

Vishal M. Gohil et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Veterinary Sciences

Emergence of virulent pseudorabies virus infection in Northern China

Rui Wu et al.

JOURNAL OF VETERINARY SCIENCE (2013)

Article Immunology

Pseudorabies Virus Variant in Bartha-K61-Vaccinated Pigs, China, 2012

Tong-Qing An et al.

EMERGING INFECTIOUS DISEASES (2013)

Review Virology

Pseudorabies virus in wild swine: a global perspective

T. Mueller et al.

ARCHIVES OF VIROLOGY (2011)

Article Cell Biology

Role of Lipids in Virus Replication

Maier Lorizate et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Article Biotechnology & Applied Microbiology

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

Vishal M. Gohil et al.

NATURE BIOTECHNOLOGY (2010)