Journal
ADVANCED OPTICAL MATERIALS
Volume 10, Issue 2, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adom.202101634
Keywords
biosafety; biotargeting ability; fluorescence quantum yield; organic second near-infrared fluorophores; signal activatable feature
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Funding
- National Natural Science Foundation of China [22077099, 21807087]
- Key Research and Development Program of Shaanxi [2019KWZ-07]
- Technology Innovation Leading Program of Shaanxi [2020TG-031]
- Xi'an City Science and Technology Project [2019218214GXRC018CG019-GXYD18.4, 2020KGRC0115]
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The review provides an overview of the development and construction of organic NIR-II fluorophores, with a focus on summarizing and discussing modulation strategies to improve their performance and functionality. The conclusion and future directions of the modulation strategy are also presented in detail.
The second near-infrared (NIR-II) window is highly effective in fluorescent bioimaging to obtain a deep view of living systems. Among numerous NIR-II fluorescent agents, organic fluorophores have been considered as ideal candidates in this field. Thus, modulation strategies should be considered to improve the performance and functionality of such agents. This review provides an overview of the development and construction of organic NIR-II fluorophores. More importantly, the modulation strategies focused on improving the performance and functionality of organic NIR-II fluorophores are summarized and discussed in detail. Furthermore, the conclusion and future directions of the modulation strategy are presented as well.
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