☆ 4.7 Article

Synergies of Human Umbilical Vein Endothelial Cell-Laden Calcium Silicate-Activated Gelatin Methacrylate for Accelerating 3D Human Dental Pulp Stem Cell Differentiation for Endodontic Regeneration

POLYMERS (2021)

Related references

Note: Only part of the references are listed.

Review Materials Science, Multidisciplinary

Materials roles for promoting angiogenesis in tissue regeneration

Jung-Hwan Lee et al.

Summary: This article discusses the importance of proangiogenic efforts in tissue repair and regeneration, focusing on the pivotal roles of engineered matrices in stimulating angiogenesis processes. The design and tuning of matrices for the proper presentation of growth factors and the sustained release of angiogenic molecules are crucial for tissue repair therapies.

PROGRESS IN MATERIALS SCIENCE (2021)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Hybrid chitosan/gelatin/nanohydroxyapatite scaffolds promote odontogenic differentiation of dental pulp stem cells and in vitro biomineralization

Georgia Vagropoulou et al.

Summary: This study demonstrates the potential of hybrid chitosan/gelatin/nanohydroxyapatite scaffolds to support viability and proliferation of dental pulp stem cells, inducing odontogenic differentiation and in vitro biomineralization without the addition of any inductive factors. The results suggest a promising strategy for tissue engineering of mineralized dental tissues.

DENTAL MATERIALS (2021)

Add to Collection

Article Polymer Science

Calcium Silicate-Activated Gelatin Methacrylate Hydrogel for Accelerating Human Dermal Fibroblast Proliferation and Differentiation

Fong-Sian Lin et al.

Summary: Infusing silicon ions into gelatin methacrylate hydrogels can enhance wound healing and skin regeneration by promoting cellular adhesion, proliferation, and secretion of important extracellular matrix proteins. This innovative approach shows promise for future clinical applications in skin regeneration.

POLYMERS (2021)

Add to Collection

Review Cell Biology

Stem Cells and Extrusion 3D Printing for Hyaline Cartilage Engineering

Oceane Messaoudi et al.

Summary: Hyaline cartilage lacks self-healing properties, making early treatment crucial to prevent long-term degradation. Cartilage tissue engineering and 3D printing offer new alternatives for addressing cartilage issues.

CELLS (2021)

Add to Collection

Article Engineering, Biomedical

3D bioprinting of prevascularised implants for the repair of critically-sized bone defects

Jessica Nulty et al.

Summary: This study developed a bioprinting strategy to engineer prevascularised tissues both in vitro and in vivo, using different bioinks, cells, and supporting cells. These prevascularised constructs were able to enhance vascularisation and regeneration of large bone defects, showing potential for new bioprinted therapeutics.

ACTA BIOMATERIALIA (2021)

Add to Collection

Article Materials Science, Biomaterials

Developing a biodegradable tricalcium silicate/glucono-delta-lactone/calcium sulfate dihydrate composite cement with high preliminary mechanical property for bone filling

Zhengwen Ding et al.

Summary: The composite cement has a shorter setting time and high initial mechanical properties, with good biodegradability and in vitro bioactivity. Cell experiments showed that appropriate concentrations of cement extract are beneficial for cell proliferation, differentiation, and extracellular matrix calcification.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection

Article Materials Science, Biomaterials

The synergistic effects of Xu Duan combined Sr-contained calcium silicate/poly-ε-caprolactone scaffolds for the promotion of osteogenesis marker expression and the induction of bone regeneration in osteoporosis

Chia-Tze Kao et al.

Summary: This study demonstrated the potential of a Chinese medicine-contained scaffold in promoting bone tissue regeneration in osteoporosis models. The scaffolds were non-toxic to cells and enhanced bone ingrowth, showing promise for future clinical applications.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection

Article Materials Science, Biomaterials

An immune regulatory 3D-printed alginate-pectin construct for immunoisolation of insulin producing ?-cells

Shuxian Hu et al.

Summary: New alginate-based bioinks were developed to produce cell-laden grid-shaped hydrogel constructs with stable integrity and immunomodulating capacity. Addition of pectin improved cell survival under inflammatory stress.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection

Article Materials Science, Multidisciplinary

Physico-chemical modification of gelatine for the improvement of 3D printability of oxidized alginate-gelatine hydrogels towards cartilage tissue engineering

T. Kreller et al.

Summary: This study utilized 3D printing to fabricate hierarchical scaffold structures mimicking the natural articular cartilage, demonstrating the possibility to enhance the printability of ADA-GEL hydrogels for cartilage tissue engineering. The modified formulation featuring increased gelatine amounts and heat pre-treatment showed tailorable printability characteristics and modifiable mechanical properties, providing a valuable approach for designing scaffolds without the need for additives or crosslinkers.

MATERIALS & DESIGN (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Alginate/gelatin encapsulation promotes NK cells differentiation potential of bone marrow resident C-kit+ hematopoietic stem cells

Ezzatollah Fathi et al.

Summary: The study investigated the effect of alginate-gelatin encapsulation on the differentiation potential of NK cells, revealing that encapsulation increased cell apoptosis and telomere length, as well as promoted NK cell differentiation through the secretion of cytokines.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Add to Collection

Review Biochemistry & Molecular Biology

VWF, Platelets and the Antiphospholipid Syndrome

Shengshi Huang et al.

Summary: APS is characterized by the presence of persistent antiphospholipid antibodies, leading to thrombosis and/or pregnancy morbidity. Laboratory criteria involve the detection of specific antibodies, while clinical criteria include different types of thrombosis. The presence of aPLs can increase the risk of arterial thrombosis by upregulating active VWF levels and promoting platelet activation.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Adipose Tissue-derived Microvascular Fragments as Vascularization Units for Dental Pulp Regeneration

Xun Xu et al.

Summary: By cotransplanting with adipose tissue-derived microvascular fragments (ad-MVFs), dental pulp stem cells (DPSCs) can be promoted to regenerate dental pulp and improve vascular formation, leading to successful dental pulp regeneration.

JOURNAL OF ENDODONTICS (2021)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Signaling Biomaterial for Dental Pulp Regeneration

Maria Luisa Leite et al.

Summary: By varying the ratio of collagen and gelatin and incorporating different concentrations of fibronectin, the study found that collagen/gelatin hydrogel with 10 mg/mL of FN exhibited potent bioactive and chemotactic effects on human apical papilla cells.

JOURNAL OF ENDODONTICS (2021)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

The Role of Small Extracellular Vesicles Derived from Lipopolysaccharide-preconditioned Human Dental Pulp Stem Cells in Dental Pulp Regeneration

Wen-Jin Chen et al.

Summary: The study demonstrated that LPS-preconditioned sEVs can enhance the proliferation, migration, angiogenesis, and differentiation of mesenchymal stem cells, leading to structurally improved regenerated tissue similar to normal dental pulp in vivo. These findings suggest that LPS-preconditioned sEVs play a significant role in dental pulp regeneration.

JOURNAL OF ENDODONTICS (2021)

Add to Collection

Article Materials Science, Biomaterials

Bioactive nanoparticle reinforced alginate/gelatin bioink for the maintenance of stem cell stemness

Jianjun Li et al.

Summary: The study showed that bioactive nanoparticles releasing silicon ions can enhance the properties of bioink, maintaining MSC stemness independently of pore structure. By adjusting the concentration of BNPs, bioink with defined stiffness for osteogenic or adipogenic potential can be designed. The optimal concentration of BNPs in alginate/gelatin hydrogel bioink effectively retains MSC stemness and supports MSC growth and desired differentiation in 3D bioprinting.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection

Article Materials Science, Biomaterials

Generating adipose stem cell-laden hyaluronic acid-based scaffolds using 3D bioprinting via the double crosslinked strategy for chondrogenesis

Swathi Nedunchezian et al.

Summary: This study focuses on constructing printable bioinks by combining adipose-derived stem cells, hyaluronic acid-based hydrogels and analyzing their ability to induce chondrogenesis using 3D bioprinting technology. The results showed that the double cross-linked HBSAC hydrogel scaffold exhibited favorable structural integrity, printability, and chondrogenic differentiation compared to traditional HA hydrogel.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection

Article Cell Biology

Bioprinting and Differentiation of Adipose-Derived Stromal Cell Spheroids for a 3D Breast Cancer-Adipose Tissue Model

Hannes Horder et al.

Summary: Biofabrication, including 3D printing technologies, is a powerful approach for designing disease models, such as in cancer research. A 3D-printed breast cancer model was developed to investigate cancer cell-adipocyte interaction, demonstrating adipogenic differentiation within printed spheroids. Co-culture of breast cancer cells with adipose tissue constructs showed reduced lipid content and ECM remodeling, highlighting the importance of cell-cell and cell-matrix interplay within tumor-stroma microenvironment.

CELLS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Biofabrication of Gingival Fibroblast Cell-Laden Collagen/Strontium-Doped Calcium Silicate 3D-Printed Bi-Layered Scaffold for Osteoporotic Periodontal Regeneration

Chen-Ying Wang et al.

Summary: The study utilized a 3D-printed cell-laden collagen/strontium-doped calcium silicate bi-layer scaffold for periodontal regeneration, showing enhanced osteoporotic bone regeneration. The scaffold increased secretion of relevant proteins and demonstrated guided periodontal regeneration, making it a potential candidate for future clinical applications.

BIOMEDICINES (2021)

Add to Collection

Article Engineering, Biomedical

Spatial micro-variation of 3D hydrogel stiffness regulates the biomechanical properties of hMSCs

Zheng Wang et al.

Summary: This study introduces a scheme using maleimide-dextran hydrogel to modify the biomechanical properties of hMSCs. The experiment demonstrates that the hydrogel triggers the formation of multicellular spheroids and can soften hMSCs by adjusting the degree of stiffness variation, allowing them to pass through micro-channels more easily.

BIOFABRICATION (2021)

Add to Collection

Article Polymer Science

The Development of Light-Curable Calcium-Silicate-Containing Composites Used in Odontogenic Regeneration

Yi-Ting Lin et al.

Summary: This study investigates the regulation of human dental pulp stem cells by new light-curable calcium silicate-containing polyethylene glycol diacrylate biocomposites in odontogenic-related regeneration. Results show the potential of these composites in dental tissue regeneration therapy, with the 30% CS-containing composite demonstrating the best performance.

POLYMERS (2021)

Add to Collection

Article Multidisciplinary Sciences

Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway

Vedanta Mehta et al.

Summary: The response of endothelial cells to mechanical forces plays a critical role in vascular health, and vascular pathologies may lead to endothelial-to-mesenchymal transition. This study identifies a unique mechanoreceptor, Alk5, and an Alk5-Shc pathway that are crucial for EndMT and atherosclerosis.

SCIENCE ADVANCES (2021)

Add to Collection

Review Cell Biology

Stem Cells as a Source of Pancreatic Cells for Production of 3D Bioprinted Bionic Pancreas in the Treatment of Type 1 Diabetes

Michal Wszola et al.

Summary: Type 1 diabetes is a common autoimmune disease that can be treated by culturing human stem cells to differentiate into insulin and glucagon-producing cells for the creation of a bionic pancreas. Solutions for post-transplant immune responses triggered by stem cell-derived pancreatic cells need further exploration.

CELLS (2021)

Add to Collection

Article Cell Biology

A Robust Protocol for Decellularized Human Lung Bioink Generation Amenable to 2D and 3D Lung Cell Culture

Mohammadhossein Dabaghi et al.

Summary: The research aimed to optimize the decellularization process of human lungs, isolate materials to prepare hydrogels that support the viability of primary lung cells in 2D and 3D culture systems.

CELLS (2021)

Add to Collection

Article Materials Science, Multidisciplinary

An immunomodulatory bioink with hollow manganese silicate nanospheres for angiogenesis

Jinfu. Wu et al.

Summary: This study developed an immunomodulatory bioink based on bioactive manganese silicate nanospheres, which could be used to 3D bioprint scaffolds supporting angiogenesis and promoting endothelial cell survival. The bioinks showed robust printability and cell viability even after 21 days of culture, providing a potential solution for vascularized tissue regeneration.

APPLIED MATERIALS TODAY (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Therapeutic Effects of the Addition of Fibroblast Growth Factor-2 to Biodegradable Gelatin/Magnesium-Doped Calcium Silicate Hybrid 3D-Printed Scaffold with Enhanced Osteogenic Capabilities for Critical Bone Defect Restoration

Wei-Yun Lai et al.

Summary: The study successfully improved the effectiveness of bone tissue regeneration by using gelatin-coated 3D-printed magnesium-doped calcium silicate scaffolds. The results demonstrated great potential for future clinical applications and studies, providing new possibilities for bone tissue engineering research.

BIOMEDICINES (2021)

Add to Collection

Article Biochemistry & Molecular Biology

3D-Printed Ginsenoside Rb1-Loaded Mesoporous Calcium Silicate/Calcium Sulfate Scaffolds for Inflammation Inhibition and Bone Regeneration

Cheng-Yu Chen et al.

Summary: The study demonstrated that a scaffold containing Ginsenoside Rb1 and mesoporous calcium silicate/calcium sulfate could promote cell proliferation and expression of osteogenic-related proteins, while effectively inhibiting inflammation. In vivo results showed that the scaffold achieved more effective hard tissue regeneration, suggesting its potential for future bone tissue engineering studies and clinical use.

BIOMEDICINES (2021)

Add to Collection

Article Materials Science, Biomaterials

Strontium-calcium phosphate hybrid cement with enhanced osteogenic and angiogenic properties for vascularised bone regeneration

Xiexing Wu et al.

Summary: A strontium-enhanced calcium phosphate hybrid cement (Sr-CPHC) was developed to improve the biological and physicochemical properties of CPC. Sr-CPHC exhibited longer initial setting time and higher compressive strength compared to CPC, showing enhanced cell activity and angiogenesis. In vivo evaluation demonstrated new bone formation in a rat model, indicating great potential for clinical applications in ischemic osteonecrosis and critical-size bone defects.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Materials Science, Biomaterials

A hierarchical scaffold with a highly pore-interconnective 3D printed PLGA/n-HA framework and an extracellular matrix like gelatin network filler for bone regeneration

Yichen Dou et al.

Summary: The study developed a hierarchical scaffold for bone repair with a hierarchical pore structure and gradient degradation performance, promoting cell adhesion and proliferation, as well as providing space for bone tissue regeneration.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Materials Science, Biomaterials

Study on strontium doped tricalcium silicate synthesized through sol-gel process

Wai-Ching Liu et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Add to Collection

Article Engineering, Biomedical

Gelatin Templated Polypeptide Co-Cross-Linked Hydrogel for Bone Regeneration

Yusen Qiao et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Enhanced Proliferation and Differentiation of Human Mesenchymal Stem Cell-laden Recycled Fish Gelatin/Strontium Substitution Calcium Silicate 3D Scaffolds

Chun-Ta Yu et al.

APPLIED SCIENCES-BASEL (2020)

Add to Collection

Article Cell Biology

Statistical Mechanics of Non-Muscle Myosin IIA in Human Bone Marrow-Derived Mesenchymal Stromal Cells Seeded in a Collagen Scaffold: A Thermodynamic Near-Equilibrium Linear System Modified by the Tripeptide Arg-Gly-Asp (RGD)

Yves Lecarpentier et al.

CELLS (2020)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

A Decellularized Matrix Hydrogel Derived from Human Dental Pulp Promotes Dental Pulp Stem Cell Proliferation, Migration, and Induced Multidirectional Differentiation In Vitro

Junda Li et al.

JOURNAL OF ENDODONTICS (2020)

Add to Collection

Article Engineering, Biomedical

Alginate/laponite hydrogel microspheres co-encapsulating dental pulp stem cells and VEGF for endodontic regeneration

Ruitao Zhang et al.

ACTA BIOMATERIALIA (2020)

Add to Collection

Article Polymer Science

Effects of Gelatin Methacrylate Bio-ink Concentration on Mechano-Physical Properties and Human Dermal Fibroblast Behavior

Ming-You Shie et al.

POLYMERS (2020)

Add to Collection

Article Engineering, Chemical

Assessment of the Release Profile of Fibroblast Growth Factor-2-Load Mesoporous Calcium Silicate/Poly-ε-caprolactone 3D Scaffold for Regulate Bone Regeneration

Chia-Tze Kao et al.

PROCESSES (2020)

Add to Collection

Article Materials Science, Multidisciplinary

Growth factors enhanced angiogenesis and osteogenesis on polydopamine coated titanium surface for bone regeneration

Jiuping Wu et al.

MATERIALS & DESIGN (2020)

Add to Collection

Article Materials Science, Biomaterials

Evaluation of mechanical strength and bone regeneration ability of 3D printed kagome-structure scaffold using rabbit calvarial defect model

Se-Hwan Lee et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Add to Collection

Article Cell Biology

Bioink Composition and Printing Parameters for 3D Modeling Neural Tissue

Valentina Fantini et al.

CELLS (2019)

Add to Collection

Article Materials Science, Biomaterials

The synergistic effects of graphene-contained 3D-printed calcium silicate/poly-ε-caprolactone scaffolds promote FGFR-induced osteogenic/angiogenic differentiation of mesenchymal stem cells

Yen-Hong Lin et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Add to Collection

Article Materials Science, Biomaterials

Gadolinium-doped mesoporous calcium silicate/chitosan scaffolds enhanced bone regeneration ability

Fang Liao et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Add to Collection

Article Cell Biology

Tumor Cells Develop Defined Cellular Phenotypes After 3D-Bioprinting in Different Bioinks

Sonja K. Schmidt et al.

CELLS (2019)

Add to Collection

Article Polymer Science

Development and Properties of Fish Gelatin/Oxidized Starch Double Network Film Catalyzed by Thermal Treatment and Schiff' Base Reaction

Yuhao Dong et al.

POLYMERS (2019)

Add to Collection

Article Cell & Tissue Engineering

Effects of concentrated growth factor on proliferation, migration, and differentiation of human dental pulp stem cells in vitro

Runze Jin et al.

JOURNAL OF TISSUE ENGINEERING (2018)

Add to Collection

Article Engineering, Biomedical

Regulation of the fate of dental-derived mesenchymal stem cells using engineered alginate-GelMA hydrogels

Sahar Ansari et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)

Add to Collection

Article Materials Science, Biomaterials

Synergistic acceleration in the osteogenic and angiogenic differentiation of human mesenchymal stem cells by calcium silicate-graphene composites

Ming-You Shie et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Add to Collection

Article Engineering, Biomedical

Engineering Photocrosslinkable Bicomponent Hydrogel Constructs for Creating 3D Vascularized Bone

Mehdi Kazemzadeh-Narbat et al.

ADVANCED HEALTHCARE MATERIALS (2017)

Add to Collection

Review Cell & Tissue Engineering

A mini review focused on the proangiogenic role of silicate ions released from silicon-containing biomaterials

Khandmaa Dashnyam et al.

JOURNAL OF TISSUE ENGINEERING (2017)

Add to Collection

Article Optics

The synergistic effect on osteogenic differentiation of human mesenchymal stem cells by diode laser-treated stimulating human umbilical vein endothelial cells

Chia-Tze Kao et al.

LASER PHYSICS LETTERS (2016)

Add to Collection

Article Multidisciplinary Sciences

Cold Water Fish Gelatin Methacryloyl Hydrogel for Tissue Engineering Application

Hee Jeong Yoon et al.

PLOS ONE (2016)

Add to Collection

Article Engineering, Biomedical

Osteogenesis and angiogenesis induced by porous beta-CaSiO3/PDLGA composite scaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways

Chen Wang et al.

BIOMATERIALS (2013)

Add to Collection

Article Engineering, Biomedical

Integrin binding and MAPK signal pathways in primary cell responses to surface chemistry of calcium silicate cements

Ming-You Shie et al.

BIOMATERIALS (2013)

Add to Collection

Article Cell & Tissue Engineering

Vasculogenic and Osteogenesis-Enhancing Potential of Human Umbilical Cord Blood Endothelial Colony-Forming Cells

Yuchun Liu et al.

STEM CELLS (2012)

Add to Collection

Review Medicine, General & Internal

Repair of bone defects with gelatin-based composites: A review

Kuo-Yu Chen et al.

BIOMEDICINE-TAIWAN (2011)

Add to Collection

Review Medicine, General & Internal

Dental caries

Robert H. Selwitz et al.

LANCET (2007)

Add to Collection

© Peeref 2019-2024. All rights reserved.