Facile Preparation of Tunicate-Inspired Chitosan Hydrogel Adhesive with Self-Healing and Antibacterial Properties

Article Polymer Science

Injectable and antibacterial ε-poly(L-lysine)-modified poly(vinyl alcohol)/chitosan/AgNPs hydrogels as wound healing dressings

Xu Yang et al.

Summary: The injectable and antibacterial hydrogels based on c-poly (L-lysine)-modified poly (vinyl alcohol)/chitosan/silver complexes displayed excellent bactericidal properties, biocompatibility, and accelerated wound healing effects.

POLYMER (2021)

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Article Chemistry, Applied

Injectable hydrogel derived from chitosan with tunable mechanical properties via hybrid-crosslinking system

Jeong Wook Seo et al.

Summary: The newly developed HBC-MA hydrogel possesses thermo-sensitive and photo-crosslinkable properties, preventing unintended loss of the graft after subcutaneous injection in mice and significantly improving mechanical strength and stability of the graft with visible light applied beneath the skin.

CARBOHYDRATE POLYMERS (2021)

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Article Engineering, Chemical

Preparation and characterization of gelatin-gallic acid/ZnO nanocomposite with antibacterial properties as a promising multi-functional bioadhesive for wound dressing applications

Sonia Nohemi Ramirez-Barron et al.

Summary: The study successfully developed a nanocomposite material with notable adhesion performance and enhanced antimicrobial properties by incorporating zinc oxide nanoparticles into gelatin-catechol matrix.

INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES (2021)

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Article Materials Science, Biomaterials

Injectable Self-Healing Hydrogels Containing CuS Nanoparticles with Abilities of Hemostasis, Antibacterial activity, and Promoting Wound Healing

Yue Kong et al.

Summary: Injectable self-healing CuS NP hydrogels with multiple functions such as hemostasis, antibacterial activity, and promotion of infected wound healing were developed and demonstrated to have promising effects in accelerating wound healing in a mouse model. These hydrogels show great potential as in situ wound dressings.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

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Article Chemistry, Multidisciplinary

Noncompressible Hemostasis and Bone Regeneration Induced by an Absorbable Bioadhesive Self-Healing Hydrogel

Weijuan Huang et al.

Summary: This research introduces a catechol-conjugated chitosan multi-functional hydrogel that can rapidly achieve adhesion and hemostasis during surgery, with self-healing capabilities. In vivo experiments using a rabbit ilium bone defect model demonstrate the rapid hemostatic effect of the hydrogel and its promotion of bone regeneration.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Correction Engineering, Biomedical

Mussel-inspired poly(γ-glutamic acid)/nanosilicate composite hydrogels with enhanced mechanical properties, tissue adhesive properties, and skin tissue regeneration (vol 123, pg 254, 2021)

Min Hee Kim et al.

ACTA BIOMATERIALIA (2021)

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Article Engineering, Environmental

Injectable self-healing CuS nanoparticle complex hydrogels with antibacterial, anti-cancer, and wound healing properties

Liangqin Zhou et al.

Summary: This study developed a CuS nanoparticle complex hydrogel system with multiple functions, including excellent self-healing ability, photothermal/photodynamic performance, and biocompatibility, for accelerating wound healing.

CHEMICAL ENGINEERING JOURNAL (2021)

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Article Chemistry, Multidisciplinary

Magnesium Oxide-Assisted Dual-Cross-Linking Bio-Multifunctional Hydrogels for Wound Repair during Full-Thickness Skin Injuries

Xiaoduo Tang et al.

Summary: The bio-multifunctional hydrogel CCOD-MgO accelerates wound healing through a double cross-linking mechanism, exhibiting high tissue adhesion, self-repair capabilities, and low swelling rate. In vitro experiments show that CCOD-MgO has higher adhesion strength and antibacterial properties compared to other hydrogels, effectively protecting wounds from infection.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Article Engineering, Biomedical

Modified hyaluronic acid hydrogels with chemical groups that facilitate adhesion to host tissues enhance cartilage regeneration

Jiaqing Chen et al.

Summary: The study developed a novel hydrogel, AHAMA hydrogel, with excellent adhesive strength and stability, capable of enhancing proliferation and migration of bone marrow stem cells. In experiments, AHAMA hydrogel demonstrated significant potential in promoting cartilage regeneration in a rat osteochondral defect model.

BIOACTIVE MATERIALS (2021)

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Article Materials Science, Biomaterials

Prevention of pulmonary air leaks using a biodegradable tissue-adhesive fiber sheet based on Alaska pollock gelatin modified with decanyl groups

Hiroaki Ichimaru et al.

Summary: Tissue adhesives derived from modified Alaska pollock gelatin with decanyl groups showed high burst strength in adhering to porcine pleura, making them promising for treating pulmonary air leaks. The interaction between the decanyl groups and hydrophobic proteins/lipid bilayers of cells contributed to the high interfacial strength between the adhesive fiber sheet and the pleura. Additionally, the adhesive material exhibited complete degradation within 21 days without severe inflammation when implanted subcutaneously in rats.

BIOMATERIALS SCIENCE (2021)

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Article Chemistry, Multidisciplinary