Optimal vaccine allocation for COVID-19 in the Netherlands: A data-driven prioritization

Article Medicine, General & Internal

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Merryn Voysey et al.

Summary: The ChAdOx1 nCoV-19 vaccine has been shown to have an acceptable safety profile and effectiveness against symptomatic COVID-19, with higher efficacy observed in the group that received a low dose followed by a standard dose.

LANCET (2021)

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Article Infectious Diseases

Impact of physical distancing measures against COVID-19 on contacts and mixing patterns: repeated cross-sectional surveys, the Netherlands, 2016-17, April 2020 and June 2020

Jantien A. Backer et al.

Summary: A survey conducted in the Netherlands showed that strict physical distancing measures significantly reduced community contact numbers, contributing to curbing the COVID-19 epidemic. Different age groups reacted differently after measures were relaxed, with children reverting to normal contact numbers and elderly individuals maintaining restricted contact levels.

EUROSURVEILLANCE (2021)

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Article Multidisciplinary Sciences

Quantifying population contact patterns in the United States during the COVID-19 pandemic

Dennis M. Feehan et al.

Summary: The study reports changes in interpersonal contact patterns in the US during the COVID-19 pandemic, finding a dramatic reduction in contacts during the first wave, with subsequent increases and certain demographic groups having significantly higher contact rates.

NATURE COMMUNICATIONS (2021)

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Article Public, Environmental & Occupational Health

The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Janssen COVID-19 Vaccine — United States, February 2021

Sara E. Oliver et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Multidisciplinary Sciences

Dynamic prioritization of COVID-19 vaccines when social distancing is limited for essential workers

Jack H. Buckner et al.

Summary: Given the limited supply of COVID-19 vaccines, it is crucial to prioritize vaccination across different age and essential worker groups to achieve public health goals, such as minimizing infections and deaths. Depending on the objectives, the prioritization order may vary, with older essential workers typically targeted first but younger essential workers or seniors prioritized based on the goal of controlling spread or mortality. Various factors such as vaccine effectiveness, supply, transmission rate, and initial infections magnitude can influence the optimal prioritization strategy.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

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Article Multidisciplinary Sciences

Vaccine optimization for COVID-19: Who to vaccinate first?

Laura Matrajt et al.

Summary: Vaccines are expected to be the best tool for controlling the COVID-19 pandemic, with high effectiveness paired with high coverage able to significantly mitigate the pandemic. Vaccine allocation strategies may vary based on vaccine effectiveness, with high-risk age groups prioritized for low effectiveness vaccines, and high-transmission age groups prioritized for high effectiveness vaccines.

SCIENCE ADVANCES (2021)

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Article Infectious Diseases