Scar Tissue after a Cesarean Section-The Management of Different Complications in Pregnant Women

The definition of a cesarean scar pregnancy (CSP) is the localization of the gestational sac (GS) in the cicatrix tissue, which is created in the front wall of the uterus after a previous cesarean section (CS). The worldwide prevalence of CSP has been growing rapidly. However, there are no general recommendations regarding prophylaxis and treatment of the abnormalities of the anterior wall of the uterus discovered in a non-pregnant myometrium, or how to deal with existing cases of CSP. We present the latest knowledge, a holistic approach to the biology, histology, imaging, and management concerning post-CS scars based on our cases, which were treated in the Department of Pregnancy and Pathology of Pregnancy in the Medical University of Lublin, Poland. In our study, we present images of tissue samples of areas with a cicatrix in the uterus, and ultrasound and MRI images of CSP. We discuss the advances in the biology of the post-CS scar tissue, the prevention techniques used to repair the scar defect (niche) before the pregnancy, and the treatment of different complications of CSP, such as the rupture of the gravid uterus or the dehiscence of the myometrium.

Automated summary

CSP is defined as the localization of the gestational sac in the cicatrix tissue created in the front wall of the uterus after a previous cesarean section. With the worldwide prevalence of CSP increasing rapidly, there is currently a lack of general recommendations for the prophylaxis and treatment of these abnormalities. Our study presents the latest knowledge and a holistic approach to the biology, histology, imaging, and management of post-CS scars based on clinical cases treated in Poland.