4.8 Article

Single-cell analysis of early chick hypothalamic development reveals that hypothalamic cells are induced from prethalamic-like progenitors

Related references

Note: Only part of the references are listed.
Article Biology

Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons

Dong Won Kim et al.

Summary: The study revealed the crucial role of Lhx6 in the survival of hypothalamic neurons, as well as explored the mechanisms underlying the development of GABAergic neurons in the hypothalamus. By identifying specific molecular mechanisms controlled by Lhx6, it sheds light on the regulation of innate behaviors such as sleep by hypothalamic neurons.

COMMUNICATIONS BIOLOGY (2021)

Article Multidisciplinary Sciences

Atoh7-independent specification of retinal ganglion cell identity

Justin Brodie-Kommit et al.

Summary: The study highlights the essential role of Atoh7 in the survival of RGCs and the presence of Atoh7-dependent and Atoh7-independent mechanisms for RGC specification. Despite the delay in RGC differentiation in Atoh7;Bax-deficient retinas, the gene expression profile of RGC precursors remains largely normal. Eventually, Atoh7;Bax-deficient RGCs mature, fire action potentials, and integrate into retinal circuitry, albeit with severe axonal guidance defects.

SCIENCE ADVANCES (2021)

Article Biotechnology & Applied Microbiology

Modular, efficient and constant-memory single-cell RNA-seq preprocessing

Pall Melsted et al.

Summary: The preprocessing workflow for single-cell RNA-seq data achieves near-optimal speed and high efficiency, demonstrating flexibility and scalability for large datasets.

NATURE BIOTECHNOLOGY (2021)

Article Multidisciplinary Sciences

Control of neurogenic competence in mammalian hypothalamic tanycytes

Sooyeon Yoo et al.

Summary: Disruption of the NFI family of transcription factors stimulates tanycyte proliferation and neurogenesis in the postnatal hypothalamus. NFI factors repress Shh and Wnt signaling in tanycytes, controlling proliferation and neurogenesis. Tanycytes deficient in Nfia/b/x give rise to various hypothalamic neuronal subtypes, suggesting potential for remodeling hypothalamic neural circuitry.

SCIENCE ADVANCES (2021)

Article Biochemical Research Methods

NicheNet: modeling intercellular communication by linking ligands to target genes

Robin Browaeys et al.

NATURE METHODS (2020)

Article Multidisciplinary Sciences

Molecular design of hypothalamus development

Roman A. Romanov et al.

NATURE (2020)

Article Biotechnology & Applied Microbiology

Generalizing RNA velocity to transient cell states through dynamical modeling

Volker Bergen et al.

NATURE BIOTECHNOLOGY (2020)

Article Multidisciplinary Sciences

Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus

Xin Zhou et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Ali Seifinejad et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemical Research Methods

Fast, sensitive and accurate integration of single-cell data with Harmony

Ilya Korsunsky et al.

NATURE METHODS (2019)

Article Multidisciplinary Sciences

Single-cell transcriptomic analysis of mouse neocortical development

Lipin Loo et al.

NATURE COMMUNICATIONS (2019)

Article Biotechnology & Applied Microbiology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler et al.

NATURE BIOTECHNOLOGY (2018)

Article Multidisciplinary Sciences

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Bora Lee et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

A Single-Cell Transcriptional Atlas of the Developing Murine Cerebellum

Robert A. Carter et al.

CURRENT BIOLOGY (2018)

Article Multidisciplinary Sciences

Developmental diversification of cortical inhibitory interneurons

Christian Mayer et al.

NATURE (2018)

Article Multidisciplinary Sciences

RNA velocity of single cells

Gioele La Manno et al.

NATURE (2018)

Article Biotechnology & Applied Microbiology

SCANPY: large-scale single-cell gene expression data analysis

F. Alexander Wolf et al.

GENOME BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Disrupted-in-Schizophrenia-1 is essential for normal hypothalamic-pituitary-interrenal (HPI) axis function

Helen Eachus et al.

HUMAN MOLECULAR GENETICS (2017)

Review Developmental Biology

Development of the hypothalamus: conservation, modification and innovation

Yuanyuan Xie et al.

DEVELOPMENT (2017)

Article Physiology

Development of the Neuroendocrine Hypothalamus

Sarah Burbridge et al.

COMPREHENSIVE PHYSIOLOGY (2016)

Article Developmental Biology

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

Florian T. Merkle et al.

DEVELOPMENT (2015)

Review Endocrinology & Metabolism

Early life origins of metabolic disease: Developmental programming of hypothalamic pathways controlling energy homeostasis

Laura Dearden et al.

FRONTIERS IN NEUROENDOCRINOLOGY (2015)

Review Anatomy & Morphology

Role of developmental factors in hypothalamic function

Jakob Biran et al.

FRONTIERS IN NEUROANATOMY (2015)

Review Developmental Biology

Patterning, specification, and differentiation in the developing hypothalamus

Joseph L. Bedont et al.

WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2015)

Editorial Material Biochemistry & Molecular Biology

The hypothalamus

Clifford B. Saper et al.

CURRENT BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell et al.

NATURE BIOTECHNOLOGY (2014)

Article Biochemistry & Molecular Biology

GEISHA: an evolving gene expression resource for the chicken embryo

Parker B. Antin et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Neurosciences

Rax Is a Selector Gene for Mediobasal Hypothalamic Cell Types

Fuqu Lu et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Developmental Biology

FGF-dependent midline-derived progenitor cells in hypothalamic infundibular development

Caroline Alayne Pearson et al.

DEVELOPMENT (2011)

Article Biochemistry & Molecular Biology

Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

Stephanie L. Padilla et al.

NATURE MEDICINE (2010)

Article Neurosciences

A genomic atlas of mouse hypothalamic development

Tomomi Shimogori et al.

NATURE NEUROSCIENCE (2010)

Review Cell Biology

Fate map of the chick embryo neural tube

Raquel Garcia-Lopez et al.

DEVELOPMENT GROWTH & DIFFERENTIATION (2009)

Review Neurosciences

The stress system in depression and neurodegeneration: Focus on the human hypothalamus

A. -M. Bao et al.

BRAIN RESEARCH REVIEWS (2008)

Article Biochemistry & Molecular Biology

The prethalamus is established during gastrulation and influences diencephalic regionalization

Nicole Staudt et al.

PLOS BIOLOGY (2007)

Article Developmental Biology

Canonical Wnt signaling through Lef1 is required for hypothalamic neurogenesis

Ji Eun Lee et al.

DEVELOPMENT (2006)

Article Developmental Biology

Directed differentiation of neural cells to hypothalamic dopaminergic neurons

K Ohyama et al.

DEVELOPMENT (2005)

Article Developmental Biology

Sim1 and Sim2 are required for the correct targeting of mammillary body axons

JF Marion et al.

DEVELOPMENT (2005)

Article Anatomy & Morphology

Regionalization in the chick of the anterior hypothalamus embryo

A Caqueret et al.

DEVELOPMENTAL DYNAMICS (2005)

Article Developmental Biology

Distinct modes of floor plate induction in the chick embryo

I Patten et al.

DEVELOPMENT (2003)