4.6 Article

Plasma MCP-1 and changes on cognitive function in community-dwelling older adults

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study

Adam M. Brickman et al.

Summary: Blood-based Alzheimer's disease biomarkers show associations with pathological and clinical diagnoses, and have predictive value for future development of clinical AD, indicating their potential for incorporation into multi-ethnic community studies.

ALZHEIMERS & DEMENTIA (2021)

Article Neurosciences

Relationship between brain AD biomarkers and episodic memory performance in healthy aging

Lou Rizzolo et al.

Summary: This study found that in a healthy late middle-aged population, scores on the Mnemonic Similarity Task were positively associated with hippocampal volume, while no association was found between memory performance and A beta and tau/neuroinflammation burden. Therefore, visual recognition memory and discrimination of lures may serve as early cognitive markers of memory decline in an older population.

BRAIN AND COGNITION (2021)

Review Medicine, General & Internal

Alzheimer's disease

Philip Scheltens et al.

Summary: Alzheimer's disease is projected to see a significant increase in prevalence in the future, with genetics playing a key role. Novel biomarkers and lifestyle-based prevention trials show promising therapeutic potential. Promising pharmacological treatments are advancing in clinical trials, targeting amyloid beta, tau, and inflammation.

LANCET (2021)

Review Medicine, General & Internal

Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease

D. O. T. Alawode et al.

Summary: Alzheimer's disease is increasingly prevalent worldwide, with a need for earlier and more secure diagnosis techniques. Current biomarker-based guidelines for AD diagnosis heavily rely on neuroimaging and CSF sampling, while blood-based biomarkers show potential for more accessible and cost-effective testing. Plasma neurofilament light chain and phosphorylated tau exhibit promise, but further comparisons are needed for p-tau to differentiate AD from non-AD dementias reliably. Plasma amyloid beta could serve as an early screening tool, but requires precise tests and robust pre-analytical protocols.

JOURNAL OF INTERNAL MEDICINE (2021)

Review Spectroscopy

The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics

Lindsay K. Pino et al.

MASS SPECTROMETRY REVIEWS (2020)

Article Geriatrics & Gerontology

Plasma amyloid is associated with the rate of cognitive decline in cognitively normal elderly: the SCIENCe project

Inge M. W. Verberk et al.

NEUROBIOLOGY OF AGING (2020)

Article Multidisciplinary Sciences

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline

Axel Montagne et al.

NATURE (2020)

Article Medicine, General & Internal

Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

Sebastian Palmqvist et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Clinical Neurology

IL-8 and MCP-1 Impact on Tau Phosphorylation and Phosphatase Activity

Margarida Vaz et al.

CURRENT ALZHEIMER RESEARCH (2020)

Article Medicine, General & Internal

Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults

Kelly Virecoulon Giudici et al.

JAMA NETWORK OPEN (2020)

Review Biochemistry & Molecular Biology

Peripheral inflammatory biomarkers in Alzheimer's disease: a brief review

Jong-Chan Park et al.

BMB REPORTS (2020)

Article Immunology

Glial activation and inflammation along the Alzheimer's disease continuum

Kaja Nordengen et al.

JOURNAL OF NEUROINFLAMMATION (2019)

Article Geriatrics & Gerontology

Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time

Brianne M. Bettcher et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Article Clinical Neurology

Inflammatory biomarkers in Alzheimer's disease plasma

Angharad R. Morgan et al.

ALZHEIMERS & DEMENTIA (2019)

Article Clinical Neurology

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis

Suzanne E. Schindler et al.

NEUROLOGY (2019)

Review Clinical Neurology

Inflammatory markers in Alzheimer's disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies

Xue-Ning Shen et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2019)

Review Clinical Neurology

Let's make microglia great again in neurodegenerative disorders

Marie-Victoire Guillot-Sestier et al.

JOURNAL OF NEURAL TRANSMISSION (2018)

Review Pharmacology & Pharmacy

Digit Symbol Substitution Test: The Case for Sensitivity Over Specificity in Neuropsychological Testing

Judith Jaeger

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2018)

Article Neurosciences

Association between Hippocampal Shape, Neuroinflammation, and Cognitive Decline in Alzheimer's Disease

Monia Cabinio et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Review Clinical Neurology

Peripheral inflammatory markers in Alzheimer's disease: a systematic review and meta-analysis of 175 studies

Ka Sing P. Lai et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)

Article Endocrinology & Metabolism

Innate Immune System and Inflammation in Alzheimer's Disease: From Pathogenesis to Treatment

Maria Serpente et al.

NEUROIMMUNOMODULATION (2014)

Article Surgery

Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and elaboration

Jan P. Vandenbroucke et al.

INTERNATIONAL JOURNAL OF SURGERY (2014)

Article Biochemical Research Methods

Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics

Kwasi G. Mawuenyega et al.

ANALYTICAL BIOCHEMISTRY (2013)

Review Immunology

The circulatory systemic environment as a modulator of neurogenesis and brain aging

Saul A. Villeda et al.

AUTOIMMUNITY REVIEWS (2013)

Article Immunology

Systemic immune system alterations in early stages of Alzheimer's disease

Rongzhen Zhang et al.

JOURNAL OF NEUROIMMUNOLOGY (2013)

Article Clinical Neurology

Amyloid-β-Associated Clinical Decline Occurs Only in the Presence of Elevated P-tau

Rahul S. Desikan et al.

ARCHIVES OF NEUROLOGY (2012)

Article Multidisciplinary Sciences

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Saul A. Villeda et al.

NATURE (2011)

Article Geriatrics & Gerontology

Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease

Daniela Galimberti et al.

NEUROBIOLOGY OF AGING (2006)

Article Immunology

Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice

Izumi Maezawa et al.

JOURNAL OF NEUROINFLAMMATION (2006)

Article Geriatrics & Gerontology

Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease

YX Sun et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2003)