4.7 Article

Production of Caffeic Acid with Co-fermentation of Xylose and Glucose by Multi-modular Engineering in Candida glycerinogenes

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Summary: The study established a stable caffeic acid biosynthesis pathway in yeast using a modified GAL regulatory system, achieving a production titer of 569.0 mg/L through combinatorial engineering strategies. This represents the highest reported titer of caffeic acid synthesized by engineered yeast to date.

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