Related references
Note: Only part of the references are listed.Inhaled fixed-dose combination powders for the treatment of respiratory infections
Ashlee D. Brunaugh et al.
EXPERT OPINION ON DRUG DELIVERY (2021)
Host-directed therapy to combat mycobacterial infections*
Gul Kilinc et al.
IMMUNOLOGICAL REVIEWS (2021)
Therapeutic host-directed strategies to improve outcome in tuberculosis
C. Young et al.
MUCOSAL IMMUNOLOGY (2020)
Treatment of Highly Drug-Resistant Pulmonary Tuberculosis
Francesca Conradie et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Pimozide Inhibits the Human Prostate Cancer Cells Through the Generation of Reactive Oxygen Species
Ukjin Kim et al.
FRONTIERS IN PHARMACOLOGY (2020)
Functional Inhibition of Host Histone Deacetylases (HDACs) Enhances in vitro and in vivo Anti-mycobacterial Activity in Human Macrophages and in Zebrafish
Josimar D. Moreira et al.
FRONTIERS IN IMMUNOLOGY (2020)
Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
Qingya Shi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Metformin as Host-Directed Therapy for TB Treatment: Scoping Review
Nikita Naicker et al.
FRONTIERS IN MICROBIOLOGY (2020)
Mycobacterial Virulence Factors: Surface-Exposed Lipids and Secreted Proteins
Angel Ly et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Mycobacterium tuberculosisCalcium Pump CtpF Modulates the Autophagosome in an mTOR-Dependent Manner
Rajni Garg et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)
Evaluation of a Library of FDA-Approved Drugs for Their Ability To Potentiate Antibiotics against Multidrug-Resistant Gram-Negative Pathogens
Charlotte K. Hind et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
Transcriptional Regulation of Autophagy: Mechanisms and Diseases
Chiara Di Malta et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
What works best for ensuring treatment adherence. Lessons from a social support program for people treated for tuberculosis in Ukraine
Zulfiya Charyeva et al.
PLOS ONE (2019)
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis
Richa Mishra et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Several Routes to the Same Destination: Inhibition of Phagosome-Lysosome Fusion by Mycobacterium tuberculosis
Claudia Carranza et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2019)
Reduced prevalence of latent tuberculosis infection in diabetes patients using metformin and statins
Matthew J. Magee et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
Repurposing Screen Identifies Unconventional Drugs With Activity Against Multidrug Resistant Acinetobacter baumannii
Yu-Shan Cheng et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2019)
Mycobacterial mannose-capped lipoarabinomannan: a modulator bridging innate and adaptive immunity
Kai-Liang Zhou et al.
EMERGING MICROBES & INFECTIONS (2019)
Host-directed therapies for bacterial and viral infections
Stefan H. E. Kaufmann et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Antibacterial activity of antipsychotic agents, their association with lipid nanocapsules and its impact on the properties of the nanocarriers and on antibacterial activity
Hassan Nehme et al.
PLOS ONE (2018)
Genome wide approaches discover novel Mycobacterium tuberculosis antigens as correlates of infection, disease, immunity and targets for vaccination
Mariateresa Coppola et al.
SEMINARS IN IMMUNOLOGY (2018)
Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials
Cornelis J. Korbee et al.
NATURE COMMUNICATIONS (2018)
CellProfiler 3.0: Next-generation image processing for biology
Claire McQuin et al.
PLOS BIOLOGY (2018)
The effect of metformin on culture conversion in tuberculosis patients with diabetes mellitus
Ye-Jin Lee et al.
KOREAN JOURNAL OF INTERNAL MEDICINE (2018)
Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells
Svenja Zielke et al.
CELL DEATH & DISEASE (2018)
Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity
Benny Zhitomirsky et al.
CELL DEATH & DISEASE (2018)
Potential Effect of Statins on Mycobacterium tuberculosis Infection
Paola Del Carmen Guerra-De-Blas et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2018)
Mechanisms and therapeutic significance of autophagy modulation by antipsychotic drugs
Ljubica Vucicevic et al.
CELL STRESS (2018)
Interaction between Mitochondrial Reactive Oxygen Species, Heme Oxygenase, and Nitric Oxide Synthase Stimulates Phagocytosis in Macrophages
Andrea Muellebner et al.
FRONTIERS IN MEDICINE (2018)
Combating Multidrug-Resistant Pathogens with Host-Directed Nonantibiotic Therapeutics
Jourdan A. Andersson et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
Christophe J. Queval et al.
CELL REPORTS (2017)
Direct targets of pSTAT5 signalling in erythropoiesis
Kevin R. Gillinder et al.
PLOS ONE (2017)
Host-directed therapies offer novel opportunities for the fight against tuberculosis
Arnaud Machelart et al.
DRUG DISCOVERY TODAY (2017)
Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy
Yuxi Zhang et al.
CELL CHEMICAL BIOLOGY (2017)
Mycobacterium tuberculosis EspB protein suppresses interferon-γ-induced autophagy in murine macrophages
DanDan Huang et al.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2016)
Preparation and Preclinical Evaluation of Inhalable Particles Containing Rapamycin and Anti-Tuberculosis Agents for Induction of Autophagy
Anuradha Gupta et al.
PHARMACEUTICAL RESEARCH (2016)
Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host
Elizabeth J. Klemm et al.
NATURE MICROBIOLOGY (2016)
Drug Repurposing Screening Identifies Novel Compounds That Effectively Inhibit Toxoplasma gondii Growth
Ashley J. Dittmar et al.
MSPHERE (2016)
Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis
Zakaria Hmama et al.
IMMUNOLOGICAL REVIEWS (2015)
The Influence of the CYP3A4*22 Polymorphism and CYP2D6 Polymorphisms on Serum Concentrations of Aripiprazole, Haloperidol, Pimozide, and Risperidone in Psychiatric Patients
Karen van der Weide et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2015)
Low Doses of Imatinib Induce Myelopoiesis and Enhance Host Anti-microbial Immunity
Ruth J. Napier et al.
PLOS PATHOGENS (2015)
Cough and the Transmission of Tuberculosis
Richard D. Turner et al.
JOURNAL OF INFECTIOUS DISEASES (2015)
Genetic susceptibility to invasive Salmonella disease
James J. Gilchrist et al.
NATURE REVIEWS IMMUNOLOGY (2015)
The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense
Michiel van der Vaart et al.
CELL HOST & MICROBE (2014)
Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways
Gajendra Kumar Azad et al.
MOLECULAR BIOLOGY REPORTS (2014)
Autophagy in Antimicrobial Immunity
Ligia C. Gomes et al.
MOLECULAR CELL (2014)
Host-Directed Antimicrobial Drugs with Broad-Spectrum Efficacy against Intracellular Bacterial Pathogens
Daniel M. Czyz et al.
MBIO (2014)
Integration of Chemical and RNAi Multiparametric Profiles Identifies Triggers of Intracellular Mycobacterial Killing
Varadharajan Sundaramurthy et al.
CELL HOST & MICROBE (2013)
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
Carmine Settembre et al.
NATURE CELL BIOLOGY (2013)
Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
Robert O. Watson et al.
CELL (2012)
Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action
Jwa-Jin Kim et al.
CELL HOST & MICROBE (2012)
Ebselen and Congeners Inhibit NADPH Oxidase 2-Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits
Susan M. E. Smith et al.
CHEMISTRY & BIOLOGY (2012)
Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of Mycobacterium tuberculosis in Human Macrophages
Heiko Bruns et al.
JOURNAL OF IMMUNOLOGY (2012)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers
Gang Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors
Erik A. Nelson et al.
BLOOD (2011)
Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis
Ruth J. Napier et al.
CELL HOST & MICROBE (2011)
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
A. Phillip West et al.
NATURE (2011)
Control of basal autophagy by calpain1 mediated cleavage of ATG5
Hong-guang Xia et al.
AUTOPHAGY (2010)
Genome-wide Analysis of the Host Intracellular Network that Regulates Survival of Mycobacterium tuberculosis
Dhiraj Kumar et al.
CELL (2010)
Therapeutic Targeting of Mitochondrial Superoxide in Hypertension
Anna E. Dikalova et al.
CIRCULATION RESEARCH (2010)
How tumour necrosis factor blockers interfere with tuberculosis immunity
J. Harris et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
The Global Burden of Nontyphoidal Salmonella Gastroenteritis
Shannon E. Majowicz et al.
CLINICAL INFECTIOUS DISEASES (2010)
Identification of Host-Dependent Survival Factors for Intracellular Mycobacterium tuberculosis through an siRNA Screen
Shilpi Jayaswal et al.
PLOS PATHOGENS (2010)
A Small-Molecule Screen Identifies the Antipsychotic Drug Pimozide as an Inhibitor of Listeria monocytogenes Infection
Linda A. Lieberman et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage
Shiny Nair et al.
JOURNAL OF IMMUNOLOGY (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
Coenraad Kuijl et al.
NATURE (2007)
Small molecule regulators of autophagy identified by an image-based high-throughput screen
Lihong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The mechanism of isoniazid killing: Clarity through the scope of genetics
Catherine Vilcheze et al.
ANNUAL REVIEW OF MICROBIOLOGY (2007)
Human IRGM induces autophagy to eliminate intracellular mycobacteria
Sudha B. Singh et al.
SCIENCE (2006)
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ- and CD40L-mediated costimulation
Frank A. W. Verreck et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2006)
The success and failure of BCG - implications for a novel tuberculosis vaccine
P Andersen et al.
NATURE REVIEWS MICROBIOLOGY (2005)
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2, macrophages subvert, immunity to (myco)bacteria
FAW Verreck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
MG Gutierrez et al.
CELL (2004)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Share Paper
