4.7 Article

Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse

Related references

Note: Only part of the references are listed.
Article Orthopedics

p21-/- Mice Exhibit Spontaneous Articular Cartilage Regeneration Post-Injury

Christina L. Jablonski et al.

Summary: The absence of p21 in mice resulted in enhanced articular cartilage regeneration post-FTCD, with increased cartilage thickness at 1 and 2 weeks post-FTCD. This study suggests that p21 plays a crucial role in endogenous articular cartilage regeneration.

CARTILAGE (2021)

Article Orthopedics

Superior mechanical recovery in male and female MRL/MpJ tendons is associated with a unique genetic profile

Nisha S. George et al.

Summary: Male Murphy Roths large (MRL/MpJ) mice show improved mechanical properties during tendon healing, regardless of sex. Comparison of gene expression profiles between MRL/MpJ and B6 tendon healing reveals differences such as lower inflammation, earlier higher expression of TGF-beta-related genes, and genes associated with enhanced cell migration in MRL/MpJ tendons.

JOURNAL OF ORTHOPAEDIC RESEARCH (2021)

Review Biochemistry & Molecular Biology

Pirfenidone: Molecular Mechanisms and Potential Clinical Applications in Lung Disease

Saleela M. Ruwanpura et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

Article Biochemistry & Molecular Biology

NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival

Katherine T. Best et al.

SCIENCE SIGNALING (2020)

Review Medical Laboratory Technology

The cellular basis of fibrotic tendon healing: challenges and opportunities

Anne E. C. Nichols et al.

TRANSLATIONAL RESEARCH (2019)

Review Cell Biology

TGF-β1/p53 signaling in renal fibrogenesis

Stephen P. Higgins et al.

CELLULAR SIGNALLING (2018)

Article Multidisciplinary Sciences

Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy

Margaret A. T. Freeberg et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression

Aimy Sebastian et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Orthopedics

Promoting effective tendon healing and remodeling

Nelly Andarawis-Puri et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2018)

Article Orthopedics

Outcomes of the six-strand M-Tang repair for zone 2 primary flexor tendon repair in 54 fingers

X. Zhou et al.

JOURNAL OF HAND SURGERY-EUROPEAN VOLUME (2017)

Article Orthopedics

Sex Differences in Tendon Structure and Function

Dylan C. Sarver et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2017)

Article Pathology

p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis

Shwetha K. Shetty et al.

AMERICAN JOURNAL OF PATHOLOGY (2017)

Article Cell Biology

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

Xiao-Ming Meng et al.

CELL DEATH & DISEASE (2016)

Article Orthopedics

Mechanisms of Tendon Injury and Repair

Stavros Thomopoulos et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2015)

Article Cell & Tissue Engineering

Loss of Tenomodulin Results in Reduced Self-Renewal and Augmented Senescence of Tendon Stem/Progenitor Cells

Paolo Alberton et al.

STEM CELLS AND DEVELOPMENT (2015)

Review Physiology

Tendon Vasculature in Health and Disease

Herbert Tempfer et al.

FRONTIERS IN PHYSIOLOGY (2015)

Article Orthopedics

Sex Differences in Outcome After an Acute Achilles Tendon Rupture

Karin Gravare Silbernagel et al.

ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE (2015)

Review Biochemistry & Molecular Biology

Regeneration of articular cartilage in healer and non-healer mice

Muhammad Farooq Rai et al.

MATRIX BIOLOGY (2014)

Article Orthopedics

The Incidence of Acute Traumatic Tendon Injuries in the Hand and Wrist: A 10-Year Population-based Study

Johanna P. de Jong et al.

CLINICS IN ORTHOPEDIC SURGERY (2014)

Article Orthopedics

Current Practice of Primary Flexor Tendon Repair A Global View

Jin Bo Tang et al.

HAND CLINICS (2013)

Review Medicine, Research & Experimental

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

Tamara Tchkonia et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Orthopedics

Smad3 binds scleraxis and mohawk and regulates tendon matrix organization

Ellora Berthet et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2013)

Article Multidisciplinary Sciences

The Paratenon Contributes to Scleraxis-Expressing Cells during Patellar Tendon Healing

Nathaniel A. Dyment et al.

PLOS ONE (2013)

Article Gastroenterology & Hepatology

Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice

Hacer Sahin et al.

HEPATOLOGY (2012)

Article Cell Biology

The superhealing MRL background improves muscular dystrophy

Ahlke Heydemann et al.

SKELETAL MUSCLE (2012)

Article Multidisciplinary Sciences

Lack of p21 expression links cell cycle control and appendage regeneration in mice

Khamilia Bedelbaeva et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

The Mohawk homeobox gene is a critical regulator of tendon differentiation

Yoshiaki Ito et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

Carol Kilkenny et al.

PLOS BIOLOGY (2010)

Article Endocrinology & Metabolism

Retained features of embryonic metabolism in the adult MRL mouse

Robert K. Naviaux et al.

MOLECULAR GENETICS AND METABOLISM (2009)

Article Anatomy & Morphology

Location of injury influences the mechanisms of both regeneration and repair within the MRL/MpJ mouse

Alice H. M. Beare et al.

JOURNAL OF ANATOMY (2006)

Article Cell Biology

Prior injury accelerates subsequent wound closure in a mouse model of regeneration

TA Davis et al.

CELL AND TISSUE RESEARCH (2005)

Article Biology

Scar-free healing: from embryonic mechanisms to adult therapeutic intervention

MWJ Ferguson et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2004)

Article Engineering, Biomedical

Regenerative versus reparative healing in tendon: A study of biomechanical and histological properties in fetal sheep

PK Beredjiklian et al.

ANNALS OF BIOMEDICAL ENGINEERING (2003)

Article Physiology

BMP7 antagonizes TGF-β-dependent fibrogenesis in mesangial cells

SN Wang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)