Journal
NUTRIENTS
Volume 14, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/nu14020268
Keywords
resistant starch; potatoes; microbiome; Faecalibacterium; precision nutrition
Categories
Funding
- Alliance for Potato Research and Education
- Texas Woman's University
Ask authors/readers for more resources
This study presents a precise nutrition model that predicts postprandial glucose response (PPGR) in overweight women following potato consumption. A randomized crossover trial was conducted with 30 overweight women, showing that most participants had favorable PPGR to cold potatoes. The model explains 32.2% of the variance and provides a tool for optimizing dietary recommendations.
Individual glycemic responses following dietary intake result from complex physiological processes, and can be influenced by physical properties of foods, such as increased resistant starch (RS) from starch retrogradation. Predictive equations are needed to provide personalized dietary recommendations to reduce chronic disease development. Therefore, a precision nutrition model predicting the postprandial glucose response (PPGR) in overweight women following the consumption of potatoes was formulated. Thirty overweight women participated in this randomized crossover trial. Participants consumed 250 g of hot (9.2 g RS) or cold (13.7 g RS) potatoes on two separate occasions. Baseline characteristics included demographics, 10-day dietary records, body composition, and the relative abundance (RA) and alpha-diversity of gut microbiota. Elastic net regression using 5-fold cross-validation predicted PPGR after potato intake. Most participants (70%) had a favorable PPGR to the cold potato. The model explained 32.2% of the variance in PPGR with the equation: 547.65 x (0 [if cold, high-RS potato], x1, if hot, low-RS potato]) + (BMI [kg/m(2)] x 40.66)-(insoluble fiber [g] x 49.35) + (Bacteroides [RA] x 8.69)-(Faecalibacterium [RA] x 73.49)-(Parabacteroides [RA] x 42.08) + (alpha-diversity x 110.87) + 292.52. This model improves the understanding of baseline characteristics that explain interpersonal variation in PPGR following potato intake and offers a tool to optimize dietary recommendations for a commonly consumed food.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available