☆ 4.7 Article

The Potential Role of Gut Microbiota in Alzheimer's Disease: From Diagnosis to Treatment

NUTRIENTS (2022)

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The beneficial effect of synbiotics consumption on Alzheimer's disease mouse model via reducing local and systemic inflammation

Shin-Meng Deng et al.

Summary: Alzheimer's disease is a neurodegenerative disease with no effective prevention or treatment, but dietary modulation of the gut-brain axis can potentially delay the progression of AD by reducing neuroinflammation and alleviating cognitive deficits.

IUBMB LIFE (2022)

Add to Collection
Article Nutrition & Dietetics

Isoorientin Affects Markers of Alzheimer's Disease via Effects on the Oral and Gut Microbiota in APP/PS1 Mice

Zhongbao Zhang et al.

Summary: This study found that isoorientin can reduce AD-related markers by modulating the oral and gut microbiota. High-dose isoorientin treatment decreased amyloid beta 42 deposition in the brain, reduced the expression of inflammatory markers, and increased the levels of anti-inflammatory factors.

JOURNAL OF NUTRITION (2022)

Add to Collection
Review Food Science & Technology

Dietary phytochemicals that influence gut microbiota: Roles and actions as anti-Alzheimer agents

Yi Wang et al.

Summary: Recent research has shown a growing interest in the relationship between dietary phytochemicals, the gut microbiota, and Alzheimer's disease. However, little discussion has been made about the detailed connections between these factors and how phytochemicals modulate gut dysbiosis induced pathologies of Alzheimer's disease. Deciphering these connections could provide insights for the development of dietary phytochemicals as anti-Alzheimer drug candidates.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Add to Collection
Review Nutrition & Dietetics

Fish intake, n-3 fatty acid body status, and risk of cognitive decline: a systematic review and a dose-response meta-analysis of observational and experimental studies

Rena Kosti et al.

Summary: A dose-response analysis was conducted to evaluate the associations between fish intake, cognitive performance, all-cause dementia or Alzheimer's Disease (AD), and the impact of EPA/DHA supplementation. The study found that protection against cognitive decline from fish intake levels off at intakes higher than 2 portions per week, likely due to the impact of EPA and DHA on executive functions, though questions remain regarding the mechanisms linking short- and long-term effects.

NUTRITION REVIEWS (2022)

Add to Collection
Review Food Science & Technology

MIND diet and cognitive performance in older adults: a systematic review

Sorayya Kheirouri et al.

Summary: The study found that adherence to the MIND diet can improve specific domain cognition and global cognitive function in older adults, possibly with more advantages compared to other plant-rich diets.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Add to Collection
Review Neurosciences

Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson's Disease

Gagandeep Kaur et al.

Summary: This article discusses the correlation between Parkinson's disease and microbial composition, emphasizing the role of the microbiome in the occurrence and pathophysiology of PD, particularly through the gut-brain axis, and the central role of dysbiosis in PD.

CURRENT NEUROPHARMACOLOGY (2021)

Add to Collection
Review Psychiatry

Use of ketogenic diets in the treatment of central nervous system diseases: a systematic review

Magnus G. Christensen et al.

Summary: This systematic review investigates the use and efficacy of ketogenic diets, modified Atkins diet, and medium-chain triglyceride diet in patients with epilepsy, Alzheimer's disease, and Parkinson's disease. The results show that ketogenic diets can reduce seizures in epilepsy patients, modified Atkins diet can improve memory in Alzheimer's patients, and medium-chain triglyceride diet can enhance motor and nonmotor functions in Parkinson's patients.

NORDIC JOURNAL OF PSYCHIATRY (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease

Laura Bonfili et al.

Summary: The gut microbiota coevolves with its host, and gut dysbiosis plays a key role in the pathogenesis of neurodegenerative disorders like Alzheimer's disease. Rational modulation of gut microbiota composition could be a promising approach for preventing or treating Alzheimer's disease.

FEBS JOURNAL (2021)

Add to Collection
Review Medicine, Research & Experimental

Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

Periyanaina Kesika et al.

Summary: Gut microbiota plays a crucial role in the development of Alzheimer's disease (AD) through dysbiosis, leading to inflammatory signaling pathway disturbances that promote neuroinflammation and neuronal death. Understanding the relationship between gut microbiota and CNS can help identify probiotic-based supplementation as a potential therapeutic option for AD.

LIFE SCIENCES (2021)

Add to Collection
Review Clinical Neurology

Emerging role of gut microbiota in modulation of neuroinflammation and neurodegeneration with emphasis on Alzheimer's disease

Divya Goyal et al.

Summary: Recent studies have shown that the gut microbiota interacts with the brain, influencing the pathogenesis of neurodegenerative diseases like Alzheimer's. The bidirectional communication between the gut and the brain suggests that the gut microbiota may play a crucial role in the development of Alzheimer's disease.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2021)

Add to Collection
Article Immunology

Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice

Namkwon Kim et al.

Summary: Alzheimer's disease is a neurodegenerative disease that causes memory and cognitive decline. Recent studies suggest that gut microbiota may play a role in the disease. In this study, fecal microbiota transplantation from 5xFAD mice into normal mice resulted in decreased neurogenesis and memory impairment.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Add to Collection
Review Gastroenterology & Hepatology

The Microbiota-Gut-Brain Axis: From Motility to Mood

Kara G. Margolis et al.

Summary: The gut-brain axis is crucial in maintaining homeostasis, with the microbiome playing a significant role in modulating signaling along this axis. This axis impacts disorders like irritable bowel syndrome and mood disorders, with serotonin being a key neurotransmitter involved in these conditions. More research is needed before these findings can be applied for diagnostic and therapeutic purposes in patient populations.

GASTROENTEROLOGY (2021)

Add to Collection
Article Clinical Neurology

Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population

Mia Nishikawa et al.

Summary: The study found that each additional gram of fructan intake was associated with a 24% lower risk for developing Alzheimer's disease. The results showed that higher dietary fructan intake is associated with a reduced risk of clinical Alzheimer's disease among older adults, with this association being significant in Hispanics.

CURRENT ALZHEIMER RESEARCH (2021)

Add to Collection
Article Medicine, Research & Experimental

Low levels of salivary lactoferrin may affect oral dysbiosis and contribute to Alzheimer's disease: A hypothesis

Ingar Olsen et al.

Summary: Recent reports suggest that reduced levels of salivary lactoferrin may be linked to amyloid beta accumulation in the brains of Alzheimer's disease patients. This could potentially trigger oral dysbiosis, leading to changes in the oral microbiota and contributing to the development of AD pathophysiology.

MEDICAL HYPOTHESES (2021)

Add to Collection
Review Nutrition & Dietetics

Ketogenic diet and cognition in neurological diseases: a systematic review

S. Pavon et al.

Summary: Despite the scarcity of scientific literature and lack of scientific rigor, studies have confirmed the effectiveness of the ketogenic diet in improving cognitive symptoms of the mentioned diseases.

NUTRITION REVIEWS (2021)

Add to Collection
Review Nutrition & Dietetics

Influence of Mediterranean Diet on Human Gut Microbiota

Giuseppe Merra et al.

Summary: Changes in gut microbiota are correlated with health status, with the Mediterranean diet shown to modulate gut microbiota, increase diversity, and potentially prevent the onset of chronic non-communicable degenerative diseases. Additional controlled intervention studies are needed to further understand the correlations between dietary patterns and gut microbiota composition and activity.

NUTRIENTS (2021)

Add to Collection
Article Nutrition & Dietetics

Altered Gut Microbial Metabolites in Amnestic Mild Cognitive Impairment and Alzheimer's Disease: Signals in Host-Microbe Interplay

Li Wu et al.

Summary: The study revealed differences in gut microbiota between patients with pre-onset amnestic mild cognitive impairment and Alzheimer's disease, with significant variances in tryptophan metabolites, short-chain fatty acids, and other metabolites between Alzheimer's disease and healthy controls. These findings suggest an association between fecal-based gut microbial signatures and the presence and progression of Alzheimer's disease, potentially providing a target for microbiota or dietary intervention in Alzheimer's disease prevention.

NUTRIENTS (2021)

Add to Collection
Review Immunology

Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions

Shireen Mohammad et al.

Summary: Diet-induced metabolic endotoxemia can lead to chronic inflammatory conditions due to changes in gut permeability, causing toxins to enter the bloodstream and triggering systemic inflammation. verschiedenen pro-inflammatory cytokines, resulting in chronic low-grade inflammation.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection
Article Agriculture, Multidisciplinary

Prebiotic Lactulose Ameliorates the Cognitive Deficit in Alzheimer's Disease Mouse Model through Macroautophagy and Chaperone-Mediated Autophagy Pathways

Yan-Suan Lee et al.

Summary: Lactulose and melibiose were found to alleviate cognitive impairments in AD mice through anti-inflammatory and autophagy mechanisms, with lactulose showing better enhancement of synaptic protein expression levels. These findings suggest that lactulose could potentially be developed as a preventive and/or therapeutic disaccharide for AD.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Add to Collection
Article Neurosciences

Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer's Disease or Mild Cognitive Impairment

Mingyan Guo et al.

Summary: This study revealed that patients newly diagnosed with AD or MCI have gut dysbiosis, characterized by a decrease in potentially protective microbiome and an increase in microbiome promoting inflammation. Furthermore, the degree of gut dysbiosis worsens as the disease progresses from MCI to AD.

JOURNAL OF ALZHEIMERS DISEASE (2021)

Add to Collection
Review Pharmacology & Pharmacy

The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology

Tejaswini Doifode et al.

Summary: Recent studies have shown the impact of the gut microbiota on various neurodegenerative diseases, including Alzheimer's disease. Understanding the role of the microbiota may offer new targets for treatment to delay, progress, or reverse AD, as well as potentially reducing the prevalence of the disease.

PHARMACOLOGICAL RESEARCH (2021)

Add to Collection
Review Nutrition & Dietetics

Crosstalk between Gut and Brain in Alzheimer's Disease: The Role of Gut Microbiota Modulation Strategies

Umair Shabbir et al.

Summary: The gut microbiota can influence brain immune homeostasis through the microbiota-gut-brain axis and play a key role in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD). Modulating GM through diet, probiotics, or fecal microbiota transplantation may represent potential therapeutic strategies in treating AD.

NUTRIENTS (2021)

Add to Collection
Article Clinical Neurology

Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer's disease progression based on the brain-gut axis through multiple integrated omics

Xinru Gu et al.

Summary: In recent research, a potential link between central and peripheral neuroinflammatory disorders in Alzheimer's disease (AD) progression was explored. Gut dysbiosis and lipid metabolism were found to be highly associated with AD-like neuroinflammation in Tg-APP/PS1 mice, with inflammatory factors, phosphatidylcholines (PCs) and specific bacteria identified as potential early diagnostic biomarkers for AD. Treatment with Huanglian Jiedu decoction (HLJDD) was shown to suppress gut dysbiosis, reduce A beta accumulation, and improve cognitive impairment by harnessing neuroinflammation.

ALZHEIMERS RESEARCH & THERAPY (2021)

Add to Collection
Article Nutrition & Dietetics

Microbiome and Human Aging: Probiotic and Prebiotic Potentials in Longevity, Skin Health and Cellular Senescence

Jacqueline Lena Boyajian et al.

Summary: The microbiome plays a crucial role in human aging through its impact on the gastrointestinal system, but its effects on skin aging are not fully understood. Cellular senescence associated with microbial imbalance can lead to various age-related pathologies, including dermatological disorders. Further research is needed to explore the gut microbiota composition under a senescent status and develop potential immunomodulatory therapies.

NUTRIENTS (2021)

Add to Collection
Review Nutrition & Dietetics

Effects of Nutrition on Cognitive Function in Adults with or without Cognitive Impairment: A Systematic Review of Randomized Controlled Clinical Trials

Laia Gutierrez et al.

Summary: New dietary approaches to prevent cognitive impairment are currently being explored. Evidence from dietary interventions, mainly from food and nutrient supplement interventions, shows inconsistent results and high heterogeneity between trials. Research has shown that dietary patterns, food, and dietary supplements can improve cognitive function in adults, with the Mediterranean diet showing promising results. However, more well-designed RCTs are needed to further guide the development of dietary approaches for cognitive impairment prevention.

NUTRIENTS (2021)

Add to Collection
Article Cell Biology

Structural and Functional Dysbiosis of Fecal Microbiota in Chinese Patients With Alzheimer's Disease

Zongxin Ling et al.

Summary: The study found that gut dysbiosis in Chinese Alzheimer's disease (AD) patients results in a decrease in bacterial diversity, a reduction in butyrate-producing genera positively correlated with cognitive scores, and an increase in lactate-producing genera inversely correlated with these indicators. This shift in gut dysbiosis contributes to immune disturbances in the host, serving as potential non-invasive biomarkers for distinguishing AD patients from controls. Additionally, altered functional modules in the gut microbiota of AD patients may produce immunomodulatory metabolites.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection
Article Geriatrics & Gerontology

Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites

Yuqing Yan et al.

Summary: This study demonstrated that Fasudil improved spatial memory in a mouse model of Alzheimer's disease. By analyzing gut microbiota and metabolites, it was found that Fasudil reversed abnormal microbiota and regulated metabolisms in AD mice, suggesting a novel therapeutic strategy for Alzheimer's disease.

FRONTIERS IN AGING NEUROSCIENCE (2021)

Add to Collection
Article Nutrition & Dietetics

Diet quality, gut microbiota, and microRNAs associated with mild cognitive impairment in middle-aged and elderly Chinese population

Xiaona Zhang et al.

Summary: This study found that better diet quality is associated with a lower risk of mild cognitive impairment (MCI), which may be mediated by the composition of the gut microbiota and miRNA expression.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2021)

Add to Collection
Article Immunology

Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis

Qing Liu et al.

Summary: The study demonstrated that prebiotic mannan oligosaccharide (MOS) significantly improved cognitive function and mental symptoms, reduced anxiety and obsessive behaviors, and enhanced neuroprotection in the 5xFAD transgenic AD mice model. MOS treatment also balanced brain oxidative status, suppressed neuroinflammatory responses, alleviated HPA-axis disorders, and prevented gut barrier damage.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Add to Collection
Review Endocrinology & Metabolism

The possibility of use of the ketogenic diet and medium chain triglycerides supplementation in the support therapy of Alzheimer disease

Dariusz Wlodarek

Summary: Limited clinical studies have shown that ketogenic diets and MCT supplementation can help reduce symptoms of Alzheimer's disease, providing a potential dietary intervention in therapy. These interventions can increase ketone bodies in the blood without drastic changes in patients' habitual diets.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2021)

Add to Collection
Review Endocrinology & Metabolism

Ketogenic diet therapy in Alzheimer's disease: an updated review

Matthieu Lilamand et al.

Summary: In conclusion, this review found that ketogenic diets or supplements can potentially offer both pathophysiological and clinical benefits in Alzheimer's disease. Preclinical studies showed a decrease in cerebral inflammation and specific features of AD under KD/KS, while human studies reported significant cognitive benefits and improved brain metabolism. Further research with biomarker-based participant selection and long-term follow-up is needed to better understand the effects of KD/KS on AD.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Gut Microbiota and Bipolar Disorder: An Overview on a Novel Biomarker for Diagnosis and Treatment

Lorenza Lucidi et al.

Summary: The gut microbiota plays a crucial role in maintaining homeostasis, growth, and digestive processes. It also influences the intercommunication system between the gut and the brain, potentially impacting the pathogenesis and clinical management of Bipolar Disorder. Current literature suggests a relationship between compositional alterations in the gut microbiota and BD, with potential benefits in treating BD symptoms through modifications in the microbiota composition. Further research is needed to explore the potential of correcting gut microbiota alterations as a novel strategy in BD management.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Review Medicine, General & Internal

The Emerging Role of Gut Microbiota in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Current Evidence and Potential Therapeutic Applications

Angelica Varesi et al.

Summary: Common symptoms of ME/CFS include pain, cognitive dysfunction, and fatigue, with gastrointestinal problems also frequently reported. Research has shown significant alterations in the gut microbiota of ME/CFS patients, which may contribute to worsening symptoms.

JOURNAL OF CLINICAL MEDICINE (2021)

Add to Collection
Article Microbiology

Impact of the Age of Cecal Material Transfer Donors on Alzheimer's Disease Pathology in 5xFAD Mice

Francesco Valeri et al.

Summary: This study investigated how cecal material from older donors may affect early pathological changes of Alzheimer's disease. While behavioral deficits were not worsened, individual brain regions (prefrontal cortex and dentate gyrus) showed increased plaque load after transfer of material from older animals.

MICROORGANISMS (2021)

Add to Collection
Article Neurosciences

Role of the gut microbiome in Alzheimer's disease

Kian Chung Chok et al.

Summary: Alzheimer's disease is the most common form of dementia, and the human gut microbiome may play a key role in its pathogenesis. Maintaining a healthy gut microbiome can help preserve brain function, while dysbiosis may accelerate the progression of the disease. Various treatment options, such as fecal microbiome transplant and antibiotics, aim to manipulate the gut microbiome to treat AD.

REVIEWS IN THE NEUROSCIENCES (2021)

Add to Collection
Article Environmental Sciences

Oral Microbiota Changes in Elderly Patients, an Indicator of Alzheimer's Disease

Yi-Fan Wu et al.

Summary: Alzheimer's disease (AD) is a neurodegenerative disease that affects older individuals, with alterations in oral microbiota potentially leading to neuroinflammation. Evaluating microbial dysbiosis biomarkers in the oral cavity through SMRT sequencing could serve as a tool for identifying AD patients.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

Add to Collection
Article Biology

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

Alessio Vittorio Colombo et al.

Summary: Microbiota-derived SCFA play a critical role in promoting A beta deposition in Alzheimer's disease by modulating the microglial phenotype along the gut-brain axis.

ELIFE (2021)

Add to Collection
Article Neurosciences

Spatial Memory and Gut Microbiota Alterations Are Already Present in Early Adulthood in a Pre-clinical Transgenic Model of Alzheimer's Disease

Paola C. Bello-Medina et al.

Summary: The 3xTg-AD mouse model shows spatial memory deficits in the early adulthood stage, with alterations in gut microbiota observed as early as 3 months old, potentially causally related to cognitive decline.

FRONTIERS IN NEUROSCIENCE (2021)

Add to Collection
Article Immunology

Exploring the microbiota-Alzheimer's disease linkage using short-term antibiotic treatment followed by fecal microbiota transplantation

Min Wang et al.

Summary: The study established a novel AD mouse model with a near-germ-free status using antibiotic treatment and fecal microbiota transplantation, demonstrating an increase in Aβ plaques and suppression of astrocyte activation surrounding the plaques following microbiota engraftment.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Add to Collection
Article Medicine, General & Internal

Cognitive function improvement after fecal microbiota transplantation in Alzheimer's dementia patient: a case report

Soo-Hyun Park et al.

Summary: After fecal microbiota transplantation (FMT) for Clostridioides difficile infection (CDI), cognitive improvement was observed, indicating a significant association between gut microbiome and neural function. Changes in microbiota composition were found in recipient feces after FMT, with genera associated with cognitive function being reported. This suggests a connection between gut microbiome and cognitive function, emphasizing the potential of FMT as a therapy for dementia patients.

CURRENT MEDICAL RESEARCH AND OPINION (2021)

Add to Collection
Article Biochemistry & Molecular Biology

Development of grape polyphenols as multi-targeting strategies for Alzheimer's disease

Farida El Gaamouch et al.

Summary: Alzheimer's disease (AD) is a prevalent neurodegenerative disease of aging, posing a major burden for patients, caregivers, and the healthcare system. Due to the complexity of AD pathophysiology and limited treatment options, there is a growing interest in the scientific community in exploring the impact of diet and nutrition on AD. Grape derived polyphenols are considered as potential novel strategies for AD treatment, showing promising results in modulating various aspects of AD pathophysiology.

NEUROCHEMISTRY INTERNATIONAL (2021)

Add to Collection
Review Nutrition & Dietetics

The Role of High Triglycerides Level in Predicting Cognitive Impairment: A Review of Current Evidence

AlMa Mihaela Dimache et al.

Summary: The burden of cognitive disorders is substantial and varies in etiology and severity. Triglyceride levels may be associated with cognitive function, but not all studies have found this link. Further research is needed to evaluate the relationship between triglycerides and cognitive impairment.

NUTRIENTS (2021)

Add to Collection
Review Nutrition & Dietetics

A Critical Review of the Study of Neuroprotective Diets to Reduce Cognitive Decline

Sally C. Duplantier et al.

Summary: Alzheimer's disease and other dementias are now the seventh leading cause of death worldwide, projected to affect 115.4 million people by 2050. While Mediterranean, DASH, and MIND diets are believed to have potential neuroprotective benefits, studies on these diet's effects have shown inconsistent results. This paper analyzed five Randomized Clinical Trials and 27 observational studies to identify gaps and challenges that may lead to inconsistent outcomes.

NUTRIENTS (2021)

Add to Collection
Review Clinical Neurology

A Systematic Review on the Feasibility of Salivary Biomarkers for Alzheimer's Disease

M. Bouftas

Summary: This systematic review analyzed studies on saliva biomarkers for diagnosing Alzheimer's disease. Out of 88 screened studies, 20 fulfilled inclusion criteria, showing that beta 42, tau, certain metabolites, and oral microbiota may serve as reliable AD diagnostic biomarkers in saliva. Future research should focus on standardizing analytical methods and validation studies with large sample sizes to ensure accuracy in clinical settings.

JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE (2021)

Add to Collection
Review Pharmacology & Pharmacy

Microbiota-Gut-Brain Axis: New Therapeutic Opportunities

Caitriona Long-Smith et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 60 (2020)

Add to Collection
Article Gastroenterology & Hepatology

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer's disease animal model

Min-Soo Kim et al.

GUT (2020)

Add to Collection
Review Nutrition & Dietetics

Probiotics and prebiotics: focus on psychiatric disorders - a systematic review

Renata S. D. Barbosa et al.

NUTRITION REVIEWS (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Ketone bodies, stress response, and redox homeostasis

Pedro Rojas-Morales et al.

REDOX BIOLOGY (2020)

Add to Collection
Review Cell Biology

Efficacy of probiotics on cognition, and biomarkers of inflammation and oxidative stress in adults with Alzheimer's disease or mild cognitive impairment - a meta-analysis of randomized controned trials

Haoyue Deng et al.

AGING-US (2020)

Add to Collection
Article Gastroenterology & Hepatology

Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

Tarini Shankar Ghosh et al.

GUT (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Lipids and Alzheimer's Disease

Yu-Chia Kao et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Article Microbiology

Lactobacillus probiotics improved the gut microbiota profile of a Drosophila melanogaster Alzheimer's disease model and alleviated neurodegeneration in the eye

F. H. P. Tan et al.

BENEFICIAL MICROBES (2020)

Add to Collection
Review Chemistry, Medicinal

On the Possible Relevance of Bottom-up Pathways in the Pathogenesis of Alzheimer's Disease

Friedrich Leblhuber et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2020)

Add to Collection
Review Nutrition & Dietetics

The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?

Fabien Magne et al.

NUTRIENTS (2020)

Add to Collection
Review Nutrition & Dietetics

Meat Consumption, Cognitive Function and Disorders: A Systematic Review with Narrative Synthesis and Meta-Analysis

Huifeng Zhang et al.

NUTRIENTS (2020)

Add to Collection
Review Nutrition & Dietetics

Dietary Approaches to Stop Hypertension (DASH) Diet and Blood Pressure Reduction in Adults with and without Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Christina D. Filippou et al.

ADVANCES IN NUTRITION (2020)

Add to Collection
Review Nutrition & Dietetics

Dietary Factors and Neurodegenerative Disorders: An Umbrella Review of Meta-Analyses of Prospective Studies

Janett Barbaresko et al.

ADVANCES IN NUTRITION (2020)

Add to Collection
Review Geriatrics & Gerontology

Resveratrol Derivatives as Potential Treatments for Alzheimer's and Parkinson's Disease

Bruno Dutra Arbo et al.

FRONTIERS IN AGING NEUROSCIENCE (2020)

Add to Collection
Article Biotechnology & Applied Microbiology

Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer's Disease

Yijing Chen et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Research Progress on Alzheimer's Disease and Resveratrol

Yan Yan et al.

NEUROCHEMICAL RESEARCH (2020)

Add to Collection
Article Clinical Neurology

Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers

Megan M. Bernath et al.

NEUROLOGY (2020)

Add to Collection
Review Pharmacology & Pharmacy

Alzheimer's disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?

Kevin Mullane et al.

BIOCHEMICAL PHARMACOLOGY (2020)

Add to Collection
Article Gastroenterology & Hepatology

Amyotrophic lateral sclerosis and intestinal microbiota-toward establishing cause and effect

Marc Gotkine et al.

GUT MICROBES (2020)

Add to Collection
Article Medicine, Research & Experimental

Rapid improvement in Alzheimer's disease symptoms following fecal microbiota transplantation: a case report

Sabine Hazan

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2020)

Add to Collection
Article Clinical Neurology

Gut metagenomics-derived genes as potential biomarkers of Parkinson's disease

Yiwei Qian et al.

BRAIN (2020)

Add to Collection
Article Neurosciences

Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells

Tyler J. Wenzel et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2020)

Add to Collection
Review Pharmacology & Pharmacy

Targeting the microbiota in pharmacology of psychiatric disorders

Alessia Pascale et al.

PHARMACOLOGICAL RESEARCH (2020)

Add to Collection
Review Nutrition & Dietetics

To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease

Maria G. Grammatikopoulou et al.

ADVANCES IN NUTRITION (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Yeast β-glucan alleviates cognitive deficit by regulating gut microbiota and metabolites in Aβ1-42-induced AD-like mice

Mengdai Xu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Add to Collection
Review Geriatrics & Gerontology

Nutritional supplements for neuropsychiatric symptoms in people with dementia: A systematic review and meta-analysis

Sandra Haider et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Pathophysiology of Type 2 Diabetes Mellitus

Unai Galicia-Garcia et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Review Neurosciences

Dietary Pattern, Diet Quality, and Dementia: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

Yi-Hsuan Liu et al.

JOURNAL OF ALZHEIMERS DISEASE (2020)

Add to Collection
Review Geriatrics & Gerontology

The Effect of Adherence to the Mediterranean Diet on Late-Life Cognitive Disorders: A Systematic Review

Federica Limongi et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2020)

Add to Collection
Article Neurosciences

Gut Microbiota and Dysbiosis in Alzheimer's Disease: Implications for Pathogenesis and Treatment

Shan Liu et al.

MOLECULAR NEUROBIOLOGY (2020)

Add to Collection
Review Nutrition & Dietetics

Relationship between Wine Consumption, Diet and Microbiome Modulation in Alzheimer's Disease

M. Victoria Moreno-Arribas et al.

NUTRIENTS (2020)

Add to Collection
Review Geriatrics & Gerontology

Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer's Disease

Feiqi Zhu et al.

FRONTIERS IN AGING NEUROSCIENCE (2020)

Add to Collection
Review Pharmacology & Pharmacy

Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An Update

Pufang Tan et al.

FRONTIERS IN PHARMACOLOGY (2020)

Add to Collection
Review Health Care Sciences & Services

Biomarkers for Alzheimer's Disease Early Diagnosis

Eva Auso et al.

JOURNAL OF PERSONALIZED MEDICINE (2020)

Add to Collection
Article Clinical Neurology

Salivary Aβ Secretion and Altered Oral Microbiome in Mouse Models of AD

Angela M. Floden et al.

CURRENT ALZHEIMER RESEARCH (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

Nicole Jacqueline Jensen et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Review Pharmacology & Pharmacy

Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease

Md. Habibur Rahman et al.

FRONTIERS IN PHARMACOLOGY (2020)

Add to Collection
Article Nutrition & Dietetics

Ketone production by ketogenic diet and by intermittent fasting has different effects on the gut microbiota and disease progression in an Alzheimer's disease rat model

Sunmin Park et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2020)

Add to Collection
Review Clinical Neurology

Alzheimer's disease: from basic science to precision medicine approach

Gianluigi Forloni

BMJ NEUROLOGY OPEN (2020)

Add to Collection
Article Nutrition & Dietetics

Dietary Interventions to Prevent or Delay Alzheimer's Disease: What the Evidence Shows

Zachary Bartochowski et al.

CURRENT NUTRITION REPORTS (2020)

Add to Collection
Review Nutrition & Dietetics

Vitamins in Alzheimer's Disease-Review of the Latest Reports

Anita Mielech et al.

NUTRIENTS (2020)

Add to Collection
Review Neurosciences

Sex differences in the hypothalamic-pituitary-adrenal axis' response to stress: an important role for gonadal hormones

Ashley L. Heck et al.

NEUROPSYCHOPHARMACOLOGY (2019)

Add to Collection
Article Immunology

Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort

Ping Liu et al.

BRAIN BEHAVIOR AND IMMUNITY (2019)

Add to Collection
Article Immunology

Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes

Hemraj B. Dodiya et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Add to Collection
Article Nutrition & Dietetics

The ketogenic diet as a potential treatment and prevention strategy for Alzheimer's disease

Gina M. Broom et al.

NUTRITION (2019)

Add to Collection
Article Microbiology

Alzheimer's Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway

John P. Haran et al.

MBIO (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Fecal metabolite of a gnotobiotic mouse transplanted with gut microbiota from a patient with Alzheimer's disease

Yusuke Fujii et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2019)

Add to Collection
Review Behavioral Sciences

Diet and Alzheimer's dementia - Nutritional approach to modulate inflammation

Katarzyna Szczechowiak et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2019)

Add to Collection
Article Clinical Neurology

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

Binyin Li et al.

ALZHEIMERS & DEMENTIA (2019)

Add to Collection
Review Biochemistry & Molecular Biology

Ketogenic Diet in Alzheimer's Disease

Marta Rusek et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Add to Collection
Article Public, Environmental & Occupational Health

Rationale and Design of the Emory Healthy Aging and Emory Healthy Brain Studies

Margarethe E. Goetz et al.

NEUROEPIDEMIOLOGY (2019)

Add to Collection
Review Physiology

THE MICROBIOTA-GUT-BRAIN AXIS

John F. Cryan et al.

PHYSIOLOGICAL REVIEWS (2019)

Add to Collection
Article Psychiatry

Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP/PS1 transgenic mice

Jing Sun et al.

TRANSLATIONAL PSYCHIATRY (2019)

Add to Collection
Article Medicine, General & Internal

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment

Ravinder Nagpal et al.

EBIOMEDICINE (2019)

Add to Collection
Article Cell Biology

Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: a potential therapeutic approach for Alzheimer's disease

Qiang Gao et al.

AGING-US (2019)

Add to Collection
Article Neurosciences

Specific nutrient patterns are associated with higher structural brain integrity in dementia-free older adults

Federica Prinelli et al.

NEUROIMAGE (2019)

Add to Collection
Review Multidisciplinary Sciences

Vulnerability of the industrialized microbiota

Justin L. Sonnenburg et al.

SCIENCE (2019)

Add to Collection
Review Nutrition & Dietetics

Ketogenic Diet and Epilepsy

Marzena Ulamek-Koziol et al.

NUTRIENTS (2019)

Add to Collection
Review Nutrition & Dietetics

Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors

Nobuo Fuke et al.

NUTRIENTS (2019)

Add to Collection
Review Nutrition & Dietetics

Gut Microbiota and Obesity: A Role for Probiotics

Ludovico Abenavoli et al.

NUTRIENTS (2019)

Add to Collection
Article Multidisciplinary Sciences

Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice

Hae-Ji Lee et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Review Geriatrics & Gerontology

Neuroinflammation and the Gut Microbiota: Possible Alternative Therapeutic Targets to Counteract Alzheimer's Disease?

Milica Cerovic et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Add to Collection
Article Geriatrics & Gerontology

Immunomodulatory effects of probiotics: Can they be used to treat allergies and autoimmune diseases?

Narges Dargahi et al.

MATURITAS (2019)

Add to Collection
Review Neurosciences

The Possibility of an Infectious Etiology of Alzheimer Disease

Ghulam M. Ashraf et al.

MOLECULAR NEUROBIOLOGY (2019)

Add to Collection
Review Nutrition & Dietetics

Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease)

Dariusz Wlodarek

NUTRIENTS (2019)

Add to Collection
Review Gastroenterology & Hepatology

Brain-Gut-Microbiota Axis in Alzheimer's Disease

Karol Kowalski et al.

JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY (2019)

Add to Collection
Review Immunology

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

Daniela Parada Venegas et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Review Food Science & Technology

Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications

Dorna Davani-Davari et al.

FOODS (2019)

Add to Collection
Review Clinical Neurology

Latest advances in cerebrospinal fluid and blood biomarkers of Alzheimer's disease

Marta Mila-Aloma et al.

THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2019)

Add to Collection
Review Clinical Neurology

The protective effects of polyphenols on Alzheimer's disease: A systematic review

Chiara Colizzi

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS (2019)

Add to Collection
Review Microbiology

What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases

Emanuele Rinninella et al.

MICROORGANISMS (2019)

Add to Collection
Article Cell Biology

Dysbiosis of gut microbiota and microbial metabolites in Parkinson's Disease

Meng-Fei Sun et al.

AGEING RESEARCH REVIEWS (2018)

Add to Collection
Article Cell Biology

Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

Gaofeng Zhan et al.

AGING-US (2018)

Add to Collection
Article Nutrition & Dietetics

Lactobacilli and bifidobacteria ameliorate memory and learning deficits and oxidative stress in β-amyloid (1-42) injected rats

Somayeh Athari Nik Azm et al.

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2018)

Add to Collection
Review Neurosciences

The Microbiota-Gut-Brain Axis in Neuropsychiatric Disorders: Patho-physiological Mechanisms and Novel Treatments

Yong-Ku Kim et al.

CURRENT NEUROPHARMACOLOGY (2018)

Add to Collection
Review Food Science & Technology

The effects of grape and red wine polyphenols on gut microbiota - A systematic review

Victoria Nash et al.

FOOD RESEARCH INTERNATIONAL (2018)

Add to Collection
Article Neurosciences

Gut Microbiota is Altered in Patients with Alzheimer's Disease

Zhen-Qian Zhuang et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Add to Collection
Article Immunology

Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease

Bo Cui et al.

JOURNAL OF NEUROINFLAMMATION (2018)

Add to Collection
Article Neurosciences

SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model

Laura Bonfili et al.

MOLECULAR NEUROBIOLOGY (2018)

Add to Collection
Article Clinical Neurology

Better diet quality relates to larger brain tissue volumes The Rotterdam Study

Pauline H. Croll et al.

NEUROLOGY (2018)

Add to Collection
Article Nutrition & Dietetics

Anti-inflammatory effect of multistrain probiotic formulation (L. rhamnosus, B. lactis, and B. longum)

Marzia Sichetti et al.

NUTRITION (2018)

Add to Collection
Review Pharmacology & Pharmacy

Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

Cesare Mancuso et al.

PHARMACOLOGICAL RESEARCH (2018)

Add to Collection
Review Nutrition & Dietetics

Changes of Colonic Bacterial Composition in Parkinson's Disease and Other Neurodegenerative Diseases

Sara Gerhardt et al.

NUTRIENTS (2018)

Add to Collection
Article Multidisciplinary Sciences

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice

David Ma et al.

SCIENTIFIC REPORTS (2018)

Add to Collection
Article Microbiology

Shifts on Gut Microbiota Associated to Mediterranean Diet Adherence and Specific Dietary Intakes on General Adult Population

Izaskun Garcia-Mantrana et al.

FRONTIERS IN MICROBIOLOGY (2018)

Add to Collection
Article Physiology

Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: A Randomized Controlled Trial

Anna Marseglia et al.

FRONTIERS IN PHYSIOLOGY (2018)

Add to Collection
Article Clinical Neurology

Effects of Oligosaccharides From Morinda officinalis on Gut Microbiota and Metabolome of APP/PS1 Transgenic Mice

Yang Xin et al.

FRONTIERS IN NEUROLOGY (2018)

Add to Collection
Review Physiology

Microbiota modulation by eating patterns and diet composition: impact on food intake

Elizabeth Klingbeil et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2018)

Add to Collection
Article Pharmacology & Pharmacy

Fecal microbiota transfer for bowel disorders: efficacy or hype?

Max Schmulson et al.

CURRENT OPINION IN PHARMACOLOGY (2018)

Add to Collection
Editorial Material Multidisciplinary Sciences

natureOUTLOOK ALZHEIMER'S DISEASE

Richard Hodson

NATURE (2018)

Add to Collection
Article Biochemistry & Molecular Biology

Regional variation limits applications of healthy gut microbiome reference ranges and disease models

Yan He et al.

NATURE MEDICINE (2018)

Add to Collection
Article Pharmacology & Pharmacy

Relevance of gutmicrobiota in cognition, behaviour and Alzheimer's disease

Vanessa de J. R. De-Paula et al.

PHARMACOLOGICAL RESEARCH (2018)

Add to Collection
Review Nutrition & Dietetics

The Gut-Brain Axis in Alzheimer's Disease and Omega-3. A Critical Overview of Clinical Trials

Francesca La Rosa et al.

NUTRIENTS (2018)

Add to Collection
Article Clinical Neurology

Does Severity of Alzheimer's Disease Contribute to Its Responsiveness to Modifying Gut Microbiota? A Double Blind Clinical Trial

Azadeh Agahi et al.

FRONTIERS IN NEUROLOGY (2018)

Add to Collection
Article Clinical Neurology

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease

Nicholas M. Vogt et al.

ALZHEIMERS RESEARCH & THERAPY (2018)

Add to Collection
Article Psychiatry

Mediterranean diet adherence and rate of cerebral Aβ-amyloid accumulation: Data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

Stephanie R. Rainey-Smith et al.

TRANSLATIONAL PSYCHIATRY (2018)

Add to Collection
Review Endocrinology & Metabolism

Microbiota and metabolic diseases

Alessia Pascale et al.

ENDOCRINE (2018)

Add to Collection
Review Neurosciences

The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease

Gerwyn Morris et al.

MOLECULAR NEUROBIOLOGY (2017)

Add to Collection
Article Neurosciences

Alzheimer's Disease Histological and Behavioral Manifestations in Transgenic Mice Correlate with Specific Gut Microbiome State

Liang Shen et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Add to Collection
Article Neurosciences

Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model

Carolin Brandscheid et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Add to Collection
Article Geriatrics & Gerontology

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

Annamaria Cattaneo et al.

NEUROBIOLOGY OF AGING (2017)

Add to Collection
Article Behavioral Sciences

Long-term multi-species Lactobacillus and Bifidobacterium dietary supplement enhances memory and changes regional brain metabolites in middle-aged rats

Caroline O'Hagan et al.

NEUROBIOLOGY OF LEARNING AND MEMORY (2017)

Add to Collection
Review Gastroenterology & Hepatology

Influence of gut microbiota on neuropsychiatric disorders

Maria Carmen Cenit et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2017)

Add to Collection
Article Geriatrics & Gerontology

Age Drives Distortion of Brain Metabolic, Vascular and Cognitive Functions, and the Gut Microbiome

Jared D. Hoffman et al.

FRONTIERS IN AGING NEUROSCIENCE (2017)

Add to Collection
Article Geriatrics & Gerontology

Prebiotic Effect of Fructooligosaccharides from Morinda officinalis on Alzheimer's Disease in Rodent Models by Targeting the Microbiota-Gut-Brain Axis

Diling Chen et al.

FRONTIERS IN AGING NEUROSCIENCE (2017)

Add to Collection
Article Geriatrics & Gerontology

16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain

David C. Emery et al.

FRONTIERS IN AGING NEUROSCIENCE (2017)

Add to Collection
Article Medicine, General & Internal

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

Stuart G. Snowden et al.

PLOS MEDICINE (2017)

Add to Collection
Article Immunology

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

Yuhai Zhao et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)

Add to Collection
Review Immunology

T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers

Anna Mietelska-Porowska et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2017)

Add to Collection
Article Psychiatry

The Current Status of the Ketogenic Diet in Psychiatry

Emmanuelle C. S. Bostock et al.

FRONTIERS IN PSYCHIATRY (2017)

Add to Collection
Article Multidisciplinary Sciences

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

T. Harach et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Article Multidisciplinary Sciences

Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease

Yodai Kobayashi et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Article Multidisciplinary Sciences

Gut microbiome alterations in Alzheimer's disease

Nicholas M. Vogt et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Review Biochemistry & Molecular Biology

Mechanisms and consequences of intestinal dysbiosis

G. Adrienne Weiss et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

Add to Collection
Review Immunology

Dysbiosis and the immune system

Maayan Levy et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Add to Collection
Review Gastroenterology & Hepatology

Fecal microbiota transplantation: in perspective

Shaan Gupta et al.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2016)

Add to Collection
Review Medicine, General & Internal

Gut Microbiota-brain Axis

Hong-Xing Wang et al.

CHINESE MEDICAL JOURNAL (2016)

Add to Collection
Review Pharmacology & Pharmacy

The Gut-Brain Axis, Including the Microbiome, Leaky Gut and Bacterial Translocation: Mechanisms and Pathophysiological Role in Alzheimer's Disease

Cristiano A. Kohler et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

Add to Collection
Article Neurosciences

Bacterial Amyloid and DNA are Important Constituents of Senile Plaques: Further Evidence of the Spirochetal and Biofilm Nature of Senile Plaques

Judith Miklossy

JOURNAL OF ALZHEIMERS DISEASE (2016)

Add to Collection
Article Geriatrics & Gerontology

Ketones block amyloid entry and improve cognition in an Alzheimer's model

Jun Xiang Yin et al.

NEUROBIOLOGY OF AGING (2016)

Add to Collection
Review Biology

Alzheimer's disease and gut microbiota

Xu Hu et al.

SCIENCE CHINA-LIFE SCIENCES (2016)

Add to Collection
Article Cell Biology

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease

Deepak Kumar Vijaya Kumar et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Add to Collection
Article Nutrition & Dietetics

The Mediterranean Diet and Cognitive Function among Healthy Older Adults in a 6-Month Randomised Controlled Trial: The MedLey Study

Alissa Knight et al.

NUTRIENTS (2016)

Add to Collection
Article Geriatrics & Gerontology

Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial

Elmira Akbari et al.

FRONTIERS IN AGING NEUROSCIENCE (2016)

Add to Collection
Review Neurosciences

Fecal Microbiota Transplantation and Its Usage in Neuropsychiatric Disorders

Alper Evrensel et al.

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2016)

Add to Collection
Review Gastroenterology & Hepatology

Fecal Microbiota Transplantation: Current Applications, Effectiveness, and Future Perspectives

Hyun Ho Choi et al.

CLINICAL ENDOSCOPY (2016)

Add to Collection
Review Gastroenterology & Hepatology

Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism

Douglas J. Morrison et al.

GUT MICROBES (2016)

Add to Collection
Review Neurosciences

The microbiome: A key regulator of stress and neuroinflammation

Kieran Rea et al.

NEUROBIOLOGY OF STRESS (2016)

Add to Collection
Article Clinical Neurology

MIND diet associated with reduced incidence of Alzheimer's disease

Martha Clare Morris et al.

ALZHEIMERS & DEMENTIA (2015)

Add to Collection
Article Immunology

Altered fecal microbiota composition in patients with major depressive disorder

Haiyin Jiang et al.

BRAIN BEHAVIOR AND IMMUNITY (2015)

Add to Collection
Article Food Science & Technology

Purification and characteristics of bifidocin A, a novel bacteriocin produced by Bifidobacterium animals BB04 from centenarians' intestine

Guorong Liu et al.

FOOD CONTROL (2015)

Add to Collection
Editorial Material Multidisciplinary Sciences

Gut microbiota and aging

Paul W. O'Toole et al.

SCIENCE (2015)

Add to Collection
Article Medicine, General & Internal

Mediterranean Diet and Age-Related Cognitive Decline A Randomized Clinical Trial

Cinta Valls-Pedret et al.

JAMA INTERNAL MEDICINE (2015)

Add to Collection
Article Cell Biology

Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia

Jerry Silver et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)

Add to Collection
Review Food Science & Technology

FUNCTIONAL MECHANISMS OF PROBIOTICS

Bijender Kumar Bajaj et al.

JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY AND FOOD SCIENCES (2015)

Add to Collection
Article Gastroenterology & Hepatology

Manipulation of the Microbiota for Treatment of IBS and IBD-Challenges and Controversies

Fergus Shanahan et al.

GASTROENTEROLOGY (2014)

Add to Collection
Review Behavioral Sciences

Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis

R. M. Stilling et al.

GENES BRAIN AND BEHAVIOR (2014)

Add to Collection
Article Neurosciences

Can a Bacterial Endotoxin be a Key Factor in the Kinetics of Amyloid Fibril Formation?

Annalia Asti et al.

JOURNAL OF ALZHEIMERS DISEASE (2014)

Add to Collection
Article Multidisciplinary Sciences

Diet rapidly and reproducibly alters the human gut microbiome

Lawrence A. David et al.

NATURE (2014)

Add to Collection
Review Geriatrics & Gerontology

Why Alzheimer trials fail: removing soluble oligomeric beta amyloid is essential, inconsistent, and difficult

William I. Rosenblum

NEUROBIOLOGY OF AGING (2014)

Add to Collection
Article Multidisciplinary Sciences

Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP

Eleonora Distrutti et al.

PLOS ONE (2014)

Add to Collection
Article Multidisciplinary Sciences

Impacts of infection with different toxigenic Clostridium difficile strains on faecal microbiota in children

Zongxin Ling et al.

SCIENTIFIC REPORTS (2014)

Add to Collection
Review Gastroenterology & Hepatology

Guidelines for Diagnosis, Treatment, and Prevention of Clostridium difficile Infections

Christina M. Surawicz et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2013)

Add to Collection
Review Biochemistry & Molecular Biology

Mediterranean diet and health

Francesco Sofi et al.

BIOFACTORS (2013)

Add to Collection
Review Neurosciences

Psychobiotics: A Novel Class of Psychotropic

Timothy G. Dinan et al.

BIOLOGICAL PSYCHIATRY (2013)

Add to Collection
Review Biotechnology & Applied Microbiology

Bacteriocin production by Bifidobacterium spp. A review

Fabio Andres Castillo Martinez et al.

BIOTECHNOLOGY ADVANCES (2013)

Add to Collection
Article Pharmacology & Pharmacy

Probucol prevents blood-brain barrier dysfunction in wild-type mice induced by saturated fat or cholesterol feeding

Ryusuke Takechi et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2013)

Add to Collection
Article Neurosciences

Determining the Presence of Periodontopathic Virulence Factors in Short-Term Postmortem Alzheimer's Disease Brain Tissue

Sophie Poole et al.

JOURNAL OF ALZHEIMERS DISEASE (2013)

Add to Collection
Article Immunology

IFN-γ Production by Amyloid β-Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease

Tara C. Browne et al.

JOURNAL OF IMMUNOLOGY (2013)

Add to Collection
Review Biochemistry & Molecular Biology

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

Gijs den Besten et al.

JOURNAL OF LIPID RESEARCH (2013)

Add to Collection
Article Clinical Neurology

Mediterranean diet improves cognition: the PREDIMED-NAVARRA randomised trial

Elena H. Martinez-Lapiscina et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2013)

Add to Collection
Review Neurosciences

Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway

Kurt Lucas et al.

MOLECULAR NEUROBIOLOGY (2013)

Add to Collection
Article Geriatrics & Gerontology

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

Yoshihiro Kashiwaya et al.

NEUROBIOLOGY OF AGING (2013)

Add to Collection
Review Immunology

Regulation of intestinal homeostasis and immunity with probiotic lactobacilli

Peter van Baarlen et al.

TRENDS IN IMMUNOLOGY (2013)

Add to Collection
Review Oncology

The microbiome and cancer

Robert F. Schwabe et al.

NATURE REVIEWS CANCER (2013)

Add to Collection
Article Immunology

Bacterial lipodipeptide, Lipid 654, is a microbiome-associated biomarker for multiple sclerosis

Vahid Farrokhi et al.

CLINICAL & TRANSLATIONAL IMMUNOLOGY (2013)

Add to Collection
Review Endocrinology & Metabolism

Probiotic Mechanisms of Action

Miriam Bermudez-Brito et al.

ANNALS OF NUTRITION AND METABOLISM (2012)

Add to Collection
Article Multidisciplinary Sciences

The link between altered cholesterol metabolism and Alzheimer's disease

Paola Gamba et al.

ENVIRONMENTAL STRESSORS IN BIOLOGY AND MEDICINE (2012)

Add to Collection
Article Behavioral Sciences

Prolonged elevation in hippocampal Aβ and cognitive deficits following repeated endotoxin exposure in the mouse

Marielle S. Kahn et al.

BEHAVIOURAL BRAIN RESEARCH (2012)

Add to Collection
Article Clinical Neurology

Increased IgA responses to the LPS of commensal bacteria is associated with inflammation and activation of cell-mediated immunity in chronic fatigue syndrome

Michael Maes et al.

JOURNAL OF AFFECTIVE DISORDERS (2012)

Add to Collection
Review Clinical Neurology

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

Gabriel S. Dichter et al.

JOURNAL OF NEURODEVELOPMENTAL DISORDERS (2012)

Add to Collection
Article Psychiatry

Platelets and Alzheimer's disease: Potential of APP as a biomarker

Genevieve Evin et al.

WORLD JOURNAL OF PSYCHIATRY (2012)

Add to Collection
Article Multidisciplinary Sciences

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Javier A. Bravo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Add to Collection
Article Multidisciplinary Sciences

Normal gut microbiota modulates brain development and behavior

Rochellys Diaz Heijtza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Add to Collection
Article Neurosciences

Immunohistological detection of Chlamydia pneumoniae in the Alzheimer's disease brain

Christine J. Hammond et al.

BMC NEUROSCIENCE (2010)

Add to Collection
Meeting Abstract Clinical Neurology

Mechanisms of ketogenic diet action

Susan A. Masino et al.

EPILEPSIA (2010)

Add to Collection
Article Neurosciences

Prion-like mechanisms in neurodegenerative diseases

Bess Frost et al.

NATURE REVIEWS NEUROSCIENCE (2010)

Add to Collection
Review Neurosciences

The blood-brain barrier and immune function and dysfunction

William A. Banks et al.

NEUROBIOLOGY OF DISEASE (2010)

Add to Collection
Article Cell Biology

Gaseotransmitters: New Frontiers for Translational Science

Csaba Szabo

SCIENCE TRANSLATIONAL MEDICINE (2010)

Add to Collection
Review Gastroenterology & Hepatology

Probiotics-host communication Modulation of signaling pathways in the intestine

Carissa M. Thomas et al.

GUT MICROBES (2010)

Add to Collection
Article Neurosciences

Increased Cerebrospinal Fluid Helicobacter Pylori Antibody in Alzheimer's Disease

Jannis Kountouras et al.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2009)

Add to Collection
Review Gastroenterology & Hepatology

Principles and clinical implications of the brain-gut-enteric microbiota axis

Sang H. Rhee et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2009)

Add to Collection
Review Gastroenterology & Hepatology

Mechanisms of Probiotic Action: Implications for Therapeutic Applications in Inflammatory Bowel Diseases

Charles Vanderpool et al.

INFLAMMATORY BOWEL DISEASES (2008)

Add to Collection
Review Behavioral Sciences

BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?

Yuan Lu et al.

NEUROBIOLOGY OF LEARNING AND MEMORY (2008)

Add to Collection
Review Neurosciences

Interaction between BDNF and serotonin: Role in mood disorders

Keri Martinowich et al.

NEUROPSYCHOPHARMACOLOGY (2008)

Add to Collection
Article Neurosciences

Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): Relevance to AD prevention

Qiu-Lan Ma et al.

JOURNAL OF NEUROSCIENCE (2007)

Add to Collection
Article Biochemistry & Molecular Biology

Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

S. A. Heldt et al.

MOLECULAR PSYCHIATRY (2007)

Add to Collection
Article Clinical Neurology

Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): Indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability

Michael Maes et al.

JOURNAL OF AFFECTIVE DISORDERS (2007)

Add to Collection
Article Clinical Neurology

ω-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease:: OmegAD study -: A randomized double-blind trial

Yvonne Freund-Levi et al.

ARCHIVES OF NEUROLOGY (2006)

Add to Collection
Article Biotechnology & Applied Microbiology

Production of bacteriocin-like inhibitory compounds by human fecal Bifidobacterium strains

MC Collado et al.

JOURNAL OF FOOD PROTECTION (2005)

Add to Collection
Review Multidisciplinary Sciences

Pathways towards and away from Alzheimer's disease

MP Mattson

NATURE (2004)

Add to Collection
Article Neurosciences

LPS-induced neuroinflammatory effects do not recover with time

B Hauss-Wegrzyniak et al.

NEUROREPORT (2000)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.