4.7 Article

Supper Timing and Cardiovascular Mortality: The Japan Collaborative Cohort Study

Journal

NUTRIENTS
Volume 13, Issue 10, Pages -

Publisher

MDPI
DOI: 10.3390/nu13103389

Keywords

cohort study; supper time; chrono-nutrition; stroke; stroke type; cardiovascular disease

Funding

  1. Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT)
  2. Priority Areas of Cancer
  3. MEXT [61010076, 62010074, 1010068, 2151065, 3151064, 4151063, 5151069, 6279102, 11181101, 17015022, 18014011, 20014026, 20390156, 26293138]
  4. JSPS KAKENH [16H06277]
  5. Ministry of Health, Labour and Welfare, Health and Labor Sciences
  6. Japan (Comprehensive Research on Cardiovascular Disease and Life-Style Related Diseases: H20-Junkankitou [Seishuu]-Ippan013
  7. H23-Junkankitou [Seishuu]-Ippan-005)

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The research found that having an irregular supper timing is associated with an increased risk of hemorrhagic stroke mortality, while there is no significant association with mortality risk from other types of stroke, coronary heart disease, and cardiovascular disease.
Evidence on the role of supper timing in the development of cardiovascular disease (CVD) is limited. In this study, we examined the associations between supper timing and risks of mortality from stroke, coronary heart disease (CHD), and total CVD. A total of 28,625 males and 43,213 females, aged 40 to 79 years, free from CVD and cancers at baseline were involved in this study. Participants were divided into three groups: the early supper group (before 8:00 p.m.), the irregular supper group (time irregular), and the late supper group (after 8:00 p.m.). Cox proportional hazards regression models were used to calculate hazard ratios (HRs) for stroke, CHD, and total CVD according to the supper time groups. During the 19-year follow-up, we identified 4706 deaths from total CVD. Compared with the early supper group, the multivariable HR of hemorrhagic stroke mortality for the irregular supper group was 1.44 (95% confidence interval [CI]: 1.05-1.97). There was no significant association between supper timing and the risk of mortality from other types of stroke, CHD, and CVD. We found that adopting an irregular supper timing compared with having dinner before 8:00 p.m. was associated with an increased risk of hemorrhagic stroke mortality.

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