Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications

Considering the future trends of biomaterials, current studies are focused on the corrosion resistance and the mechanical properties of new materials that need to be considered in the process of strengthening alloys with additive non-toxic elements. Many kinds of titanium alloys with different biocompatible elements (Mo, Si, Zr, etc.,) have been recently developed for their similar properties with human bone. Four new different alloys were obtained and investigated regarding their microstructure, mechanical, chemical, and biological behavior (in vitro and in vivo evaluation), the alloys are as follows: Ti15Mo7Zr15Ta, Ti15Mo7Zr15Ta0.5Si, Ti15Mo7Zr15Ta0.75Si, and Ti15Mo7Zr15Ta1Si. There were changes with the addition of the silicon element such as the hardness and the modulus of elasticity increased. An MTT assay confirmed the in vitro cytocompatibility of the prepared alloys.

Automated summary

Future trends in biomaterials focus on corrosion resistance and mechanical properties of new materials for strengthening alloys. Many titanium alloys with biocompatible elements similar to human bone have been developed. The addition of silicon element has shown increased hardness and modulus of elasticity in the alloys.