Influence of Selected Ophthalmic Fluids on the Wettability and Hydration of Hydrogel and Silicone Hydrogel Contact Lenses-In Vitro Study

This study attempts to evaluate the effect of incubation in selected ophthalmic fluids on contact lenses (Etafilcon A, Omafilcon A, Narafilcon A, Senofilcon A). Four research groups differing in the incubation environment were created: (1) initial state, (2) contact lens solution (CLS), (3) contact lens solution and eye drops (ED) and (4) eye drops. Dehydration by gravimetric method and the contact angle (CA) by the sessile drop method were tested. The surface free energy (SFE) was also calculated with the use of several methods: Owens-Wendt, Wu, Neumann, and Neumann-Kwok. The greatest changes in the dehydration profile were observed for contact lenses incubated in ED. The most noticeable changes in CA values were observed for contact lenses incubated in ED, in which it was not possible to settle water drop after incubation. On the basis of SFE analysis, higher values were found for hydrogel contact lenses, e.g., according to the Owens-Wendt method, they ranged from 54.45 & PLUSMN; 6.56 mJ/m(2) to 58.09 & PLUSMN; 4.86 mJ/m(2), while in the case of silicone-hydrogel contact lenses, they ranged from 32.86 & PLUSMN; 3.47 mJ/m(2)& nbsp;to 35.33 & PLUSMN; 6.56 mJ/m(2). Incubation in all tested environments decreased the SFE values, but the differences were in most cases statistically insignificant. Calculating the SFE may be a useful method as it can be used to estimate the possibility of bacteria adhering to contact lens surfaces.

Automated summary

This study evaluates the effect of incubation in ophthalmic fluids on different types of contact lenses. The results show significant changes in dehydration and contact angle for lenses incubated in eye drops. Hydrogel lenses have higher surface free energy values. The differences in SFE values caused by different incubation environments are not significant.