4.6 Article

Role of Silver Nanoparticle-Doped 2-Aminodiphenylamine Polymeric Material in the Detection of Dopamine (DA) with Uric Acid Interference

Journal

MATERIALS
Volume 15, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/ma15041308

Keywords

dopamine; silver nanoparticles; cyclic voltammetry; uric acid; electrochemical methods

Funding

  1. Department of Chemistry. of Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India
  2. Taif University TURSP program [TURSP-2020/53]

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A viable electrochemical approach using a silver nanoparticle-doped 2-aminodiphenylamine electrode has been developed for the detection of dopamine in uric acid. This method shows outstanding sensitivity, selectivity, and strength, making it suitable for pharmaceutical and biological specimen analysis.
A viable electrochemical approach for the detection of dopamine (DA) in uric acid (UA) utilizing a silver nanoparticle-doped 2-aminodiphenylamine (AgNPs-2ADPA) electrode was invented. The electrochemical performance of DA showed that the incorporated electrode displayed outstanding electrocatalytic performance to the electrochemical oxidation of DA. In our study, the AgNPs-2ADPA exhibits remarkable catalytic activity, retaining high current value and resilience when employed as a working electrode component for electrocatalytic detection of DA. We have also utilized the bare and polymeric-2ADPA in DA detection for a comparison study. This method offers a facile route with extraordinary sensitivity, selectivity, and strength for the voltammetric detection of DA, even in the presence of UA and ascorbic acid (AA) as interferents, that can be employed for pharmaceutical and biological specimens.

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