4.3 Review

A review of topical vitamin C derivatives and their efficacy

Journal

JOURNAL OF COSMETIC DERMATOLOGY
Volume 21, Issue 6, Pages 2349-2359

Publisher

WILEY
DOI: 10.1111/jocd.14465

Keywords

anti-aging products; antioxidant; cosmetic chemistry; cosmetic dermatology; topical anti-aging; vitamin C

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This review evaluates the differences between various vitamin C derivatives designed for cosmeceutical use and their efficacy, highlighting the importance of vitamin C in maintaining and improving skin health, as well as the characteristics of these derivatives.
Vitamin C is a popular ingredient in over-the-counter cosmeceuticals due to its many biological functions in maintaining and improving skin health by treating UV damage, improving discoloration, and boosting collagen production. Several chemically modified derivatives of vitamin C have been developed in an attempt to increase the stability, percutaneous absorption, and overall activity of this ingredient in topical formulations. The goal of this review is to evaluate the differences between vitamin C derivatives that have been designed for cosmeceutical use and their efficacy.

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