CASE REPORT Vena Cava and Pancreatic head En Bloc Resection for an Invasive Inferior Vena Cava Leiomyosarcoma in a Liver Transplant Patient

Background: De novo neoplasms are one of the major causes of death in patients after the first year of liver transplantation. The occurrence of sarcomas is extremely rare and the survival is often poor. However, early diagnosis and radical surgical treatment, may benefit some select liver transplant patients. Method: We describe the case of a liver transplant patient who developed a locally advanced inferior vena cava (IVC) leiomyosarcoma, who underwent radical surgical treatment with resection of the IVC associated with duodenopancreatectomy, right nephrectomy, and IVC recon-struction. We address aspects of the diagnosis and surgical strategy. Conclusion: This case report illustrates that IVC and multivisceral resections may be feasible and safe in highly selected liver transplant recipients. Major surgery should not be excluded as treatment option in an immunosuppressed liver transplant patient. (c) 2021 Elsevier Masson SAS. All rights reserved.

Automated summary

Surgical treatment for advanced leiomyosarcoma in liver transplant patients, such as resection of IVC and multiple organs, can be feasible and safe in highly selected cases. Major surgery should not be ruled out as a treatment option for immunosuppressed liver transplant recipients.