Related references
Note: Only part of the references are listed.Localized reconstruction in Scipion expedites the analysis of symmetry mismatches in cryo-EM data
Vahid Abrishami et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2021)
The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
Ahmad F. Alghanem et al.
ELIFE (2021)
SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism
Ashutosh Kumar et al.
ELIFE (2020)
A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21
Steven A. Kliewer et al.
CELL METABOLISM (2019)
Comparison of the Effects of Glucagon-Like Peptide Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors for Prevention of Major Adverse Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus Systematic Review and Meta-Analysis of Cardiovascular Outcomes Trials
Thomas A. Zelniker et al.
CIRCULATION (2019)
Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus
Eri T. Kato et al.
CIRCULATION (2019)
Dapagliflozin and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Previous Myocardial Infarction Subanalysis From the DECLARE-TIMI 58 Trial
Remo H. M. Furtado et al.
CIRCULATION (2019)
Heart Disease and Stroke Statistics-2019 Update A Report From the American Heart Association
Emelia J. Benjamin et al.
CIRCULATION (2019)
Involvement of the TREK-1 channel in human alveolar cell membrane potential and its regulation by inhibitors of the chloride current
Rita Canella et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Diabetes Mellitus-Related All-Cause and Cardiovascular Mortality in a National Cohort of Adults
Sridharan Raghavan et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)
Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
David M. Kern et al.
ELIFE (2019)
The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis
Zobair M. Younossi et al.
JOURNAL OF HEPATOLOGY (2019)
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Dorothee Liebschner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2019)
Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele
P. G. Middleton et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Molecular chaperones and protein quality control: an introduction to the JBC Reviews thematic series
Johannes Buchner
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
S. D. Wiviott et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel
Aqeela Afzal et al.
PHYSIOLOGICAL REPORTS (2019)
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
Thomas D. Goddard et al.
PROTEIN SCIENCE (2018)
MolProbity: More and better reference data for improved all-atom structure validation
Christopher J. Williams et al.
PROTEIN SCIENCE (2018)
Hemoglobin A(1c) Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians
Amir Qaseem et al.
ANNALS OF INTERNAL MEDICINE (2018)
Economic Costs of Diabetes in the US in 2017
Wenya Yang et al.
DIABETES CARE (2018)
Mechanisms of NAFLD development and therapeutic strategies
Scott L. Friedman et al.
NATURE MEDICINE (2018)
LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion
Till Stuhlmann et al.
NATURE COMMUNICATIONS (2018)
SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia
Chen Kang et al.
NATURE COMMUNICATIONS (2018)
Canagliflozin for Primary and Secondary Prevention of Cardiovascular Events: Results From the CANVAS Program (Canagliflozin Cardiovascular Assessment Study)
Kenneth W. Mahaffey et al.
CIRCULATION (2018)
Structure of a volume-regulated anion channel of the LRRC8 family
Dawid Deneka et al.
NATURE (2018)
Cryo-EM structures of the human volume-regulated anion channel LRRC8
Go Kasuya et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Structure of the human volume regulated anion channel
Jennifer M. Kefauver et al.
ELIFE (2018)
Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Melanie J. Davies et al.
DIABETES CARE (2018)
VX-659-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles
J. C. Davies et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Diabetes Treatment, Control, and Hospitalization Among Adults Aged 18 to 44 in Minnesota, 2013-2015
Emily Styles et al.
PREVENTING CHRONIC DISEASE (2018)
Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells
Nina H. Pipalia et al.
JOURNAL OF LIPID RESEARCH (2017)
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
Yanhui Zhang et al.
NATURE CELL BIOLOGY (2017)
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Shawn Q. Zheng et al.
NATURE METHODS (2017)
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
Bruce Neal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity
Adam J. Rauckhorst et al.
MOLECULAR METABOLISM (2017)
Induction of adipose and hepatic SWELL1 expression is required for maintaining systemic insulin-sensitivity in obesity
Litao Xie et al.
CHANNELS (2017)
Molecular features and physiological roles of K+-Cl- cotransporter 4 (KCC4)
A. A. Marcoux et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2017)
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
Ruhma Syeda et al.
CELL (2016)
Rates and predictors of hypoglycaemia in 27 585 people from 24 countries with insulin-treated type 1 and type 2 diabetes: the global HAT study
K. Khunti et al.
DIABETES OBESITY & METABOLISM (2016)
Global Epidemiology of Nonalcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence, and Outcomes
Zobair M. Younossi et al.
HEPATOLOGY (2016)
Pharmacological Correction of Trafficking Defects in ATP-sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations
Gregory M. Martin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The ICl,swell inhibitor DCPIB blocks Kir channels that possess weak affinity for PIP2
Wu Deng et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY – CLINICAL PRACTICE GUIDELINES FOR DEVELOPING A DIABETES MELLITUS COMPREHENSIVE CARE PLAN – 2015 —EXECUTIVE SUMMARY
Yehuda Handelsman et al.
Endocrine Practice (2015)
Inhibition of gastric H+,K+-ATPase by 4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid (DCPIB), an inhibitor of volume-regulated anion channel
Takuto Fujii et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
Alexis Rohou et al.
JOURNAL OF STRUCTURAL BIOLOGY (2015)
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Bernard Zinman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Prevalence and Incidence of Hypoglycaemia in 532,542 People with Type 2 Diabetes on Oral Therapies and Insulin: A Systematic Review and Meta-Analysis of Population Based Studies
Chloe L. Edridge et al.
PLOS ONE (2015)
Addressing Unmet Medical Needs in Type 2 Diabetes: A Narrative Review of Drugs under Development
Friedrich Mittermayer et al.
CURRENT DIABETES REVIEWS (2015)
Regulation of glucose and lipid homeostasis by adiponectin: Effects on hepatocytes, pancreatic beta cells and adipocytes
Caroline Tao et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
Zhaozhu Qiu et al.
CELL (2014)
Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding
Kathleen R. Markan et al.
DIABETES (2014)
Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function
Lalit Kumar et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Establishment of a General NAFLD Scoring System for Rodent Models and Comparison to Human Liver Pathology
Wen Liang et al.
PLOS ONE (2014)
Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC
Felizia K. Voss et al.
SCIENCE (2014)
Regulation of Insulin Secretion in Human Pancreatic Islets
Patrik Rorsman et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)
The inhibitor of volume-regulated anion channels DCPIB activates TREK potassium channels in cultured astrocytes
L. Minieri et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Carbamazepine as a Novel Small Molecule Corrector of Trafficking-impaired ATP-sensitive Potassium Channels Identified in Congenital Hyperinsulinism
Pei-Chun Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
DCPIB, the Proposed Selective Blocker of Volume-Regulated Anion Channels, Inhibits Several Glutamate Transport Pathways in Glial Cells
Nicole H. Bowens et al.
MOLECULAR PHARMACOLOGY (2013)
Endoplasmic Reticulum Stress and Type 2 Diabetes
Sung Hoon Back et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Diabetes Mellitus and the β Cell: The Last Ten Years
Frances M. Ashcroft et al.
CELL (2012)
A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
Jalal Taneera et al.
CELL METABOLISM (2012)
Endoplasmic Reticulum Stress in the β-Cell Pathogenesis of Type 2 Diabetes
Sung Hoon Back et al.
EXPERIMENTAL DIABETES RESEARCH (2012)
Endoplasmic reticulum stress, obesity and diabetes
Miriam Cnop et al.
TRENDS IN MOLECULAR MEDICINE (2012)
Pharmacological correctors of mutant CFTR mistrafficking
Nicoletta Pedemonte et al.
FRONTIERS IN PHARMACOLOGY (2012)
Diabetes Mellitus, Fasting Glucose, and Risk of Cause-Specific Death
Sreenivasa Rao Kondapally Seshasai et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
Nina H. Pipalia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
Julio E. Ayala et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2011)
The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis
Lisa B. Van Wagner et al.
Therapeutic Advances in Gastroenterology (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice
Hana Inoue et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
N. Sarwar et al.
LANCET (2010)
Sulfonylurea Receptor 1 Mutations That Cause Opposite Insulin Secretion Defects with Chemical Chaperone Exposure
Emily B. Pratt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Correctors promote folding of the CFTR in the endoplasmic reticulum
Tip W. Loo et al.
BIOCHEMICAL JOURNAL (2008)
The effect of rosiglitazone on the liver: Decreased gluconeogenesis in patients with type 2 diabetes
A Gastaldelli et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
Automated electron microscope tomography using robust prediction of specimen movements
DN Mastronarde
JOURNAL OF STRUCTURAL BIOLOGY (2005)
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
DE Kleiner et al.
HEPATOLOGY (2005)
Functional and molecular defects of pancreatic islets in human type 2 diabetes
S Del Guerra et al.
DIABETES (2005)
LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins
K Kubota et al.
FEBS LETTERS (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans
A Sawada et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic β-cell function
AK Busch et al.
DIABETES (2002)
Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle
JK Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Share Paper
