Related references
Note: Only part of the references are listed.A method for characterizing Cas9 variants via a one-million target sequence library of self-targeting sgRNAs
Andras Talas et al.
NUCLEIC ACIDS RESEARCH (2021)
5′ modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage
Grace Mullally et al.
NUCLEIC ACIDS RESEARCH (2020)
Bridge Helix of Cas9 Modulates Target DNA Cleavage and Mismatch Tolerance
Kesavan Babu et al.
BIOCHEMISTRY (2019)
sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing
Robin Graf et al.
CELL REPORTS (2019)
Limits in accuracy and a strategy of RNA structure prediction using experimental information
Jian Wang et al.
NUCLEIC ACIDS RESEARCH (2019)
Simultaneous precise editing of multiple genes in human cells
Stephan Riesenberg et al.
NUCLEIC ACIDS RESEARCH (2019)
Search-and-replace genome editing without double-strand breaks or donor DNA
Andrew V. Anzalone et al.
NATURE (2019)
Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning
Daqi Wang et al.
NATURE COMMUNICATIONS (2019)
ClinVar: improving access to variant interpretations and supporting evidence
Melissa J. Landrum et al.
NUCLEIC ACIDS RESEARCH (2018)
Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells
Stephan Riesenberg et al.
NATURE COMMUNICATIONS (2018)
The CRISPR tool kit for genome editing and beyond
Mazhar Adli
NATURE COMMUNICATIONS (2018)
The Current State and Future of CRISPR-Cas9 gRNA Design Tools
Laurence O. W. Wilson et al.
FRONTIERS IN PHARMACOLOGY (2018)
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
Christopher A. Vakulskas et al.
NATURE MEDICINE (2018)
Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array
Bernd Zetsche et al.
NATURE BIOTECHNOLOGY (2017)
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
Hao Yin et al.
NATURE BIOTECHNOLOGY (2017)
Analyzing CRISPR genome-editing experiments with CRISPResso
Luca Pinello et al.
NATURE BIOTECHNOLOGY (2016)
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
John G. Doench et al.
NATURE BIOTECHNOLOGY (2016)
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
Fuguo Jiang et al.
SCIENCE (2016)
Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes
C. D. Richardson et al.
NATURE COMMUNICATIONS (2016)
Internal guide RNA interactions interfere with Cas9-mediated cleavage
Summer B. Thyme et al.
NATURE COMMUNICATIONS (2016)
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
Maximilian Haeussler et al.
GENOME BIOLOGY (2016)
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
Ayal Hendel et al.
NATURE BIOTECHNOLOGY (2015)
CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo
Miguel A. Moreno-Mateos et al.
NATURE METHODS (2015)
Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality
Alexandra E. Briner et al.
MOLECULAR CELL (2014)
leeHom: adaptor trimming and merging for Illumina sequencing reads
Gabriel Renaud et al.
NUCLEIC ACIDS RESEARCH (2014)
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
Baohui Chen et al.
CELL (2013)
RNAstructure: web servers for RNA secondary structure prediction and analysis
Stanislav Bellaousov et al.
NUCLEIC ACIDS RESEARCH (2013)
High-resolution reversible folding of hyperstable RNA tetraloops using molecular dynamics simulations
Alan A. Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform
Martin Kircher et al.
NUCLEIC ACIDS RESEARCH (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Integrative genomics viewer
James T. Robinson et al.
NATURE BIOTECHNOLOGY (2011)
The Sequence Alignment/Map format and SAMtools
Heng Li et al.
BIOINFORMATICS (2009)
Share Paper
