Related references
Note: Only part of the references are listed.Syntheses of Atypically Fluorinated Peptidyl Macrocycles through Sequential Vinylic Substitutions
Tomoyuki Tsunemi et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
De Novo Hydrocarbon-Stapling Design of Single-Turn α-Helical Antimicrobial Peptides
Zhixia Chen et al.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2020)
Macropinocytosis as a Key Determinant of Peptidomimetic Uptake in Cancer Cells
Daniel Y. Yoo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Exposing the Nucleation Site in α-Helix Folding: A Joint Experimental and Simulation Study
Arusha Acharyya et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2019)
Investigation of the Amide Proton Solvent Exchange Properties of Glycosaminoglycan Oligosaccharides
Andrew R. Green et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2019)
Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide
Patrick G. Dougherty et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
In Situ Cyclization of Native Proteins: Structure-Based Design of a Bicyclic Enzyme
Marta Pelay-Gimeno et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Design of a Short Thermally Stable -Helix Embedded in a Macrocycle
Haifan Wu et al.
CHEMBIOCHEM (2018)
Effects of lysine-to-arginine substitution on antimicrobial activity of cationic stapled heptapeptides
Huy X. Luong et al.
ARCHIVES OF PHARMACAL RESEARCH (2018)
Determining Cysteines Available for Covalent Inhibition Across the Human Kinome
Zheng Zhao et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Double quick, double click reversible peptide stapling
Claire M. Grison et al.
CHEMICAL SCIENCE (2017)
OpenMM 7: Rapid development of high performance algorithms for molecular dynamics
Peter Eastman et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Bridging Microscopic and Macroscopic Mechanisms of p53-MDM2 Binding with Kinetic Network Models
Guangfeng Zhou et al.
BIOPHYSICAL JOURNAL (2017)
Stabilizing Fluorine-π Interactions
Ping Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
MSMBuilder: Statistical Models for Biomolecular Dynamics
Matthew P. Harrigan et al.
BIOPHYSICAL JOURNAL (2017)
Positioning a Carbon-Fluorine Bond over the π Cloud of an Aromatic Ring: A Different Type of Arene Activation
Maxwell Gargiulo Holl et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Targeting protein-protein interactions, a wide open field for drug design
May Bakail et al.
COMPTES RENDUS CHIMIE (2016)
Using Kinetic Network Models To Probe Non-Native Salt-Bridge Effects on α-Helix Folding
Guangfeng Zhou et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2016)
Using Protein-Confined Proximity To Determine Chemical Reactivity
Tomonori Kobayashi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
Gregory H. Bird et al.
NATURE CHEMICAL BIOLOGY (2016)
Small molecules, big targets: drug discovery faces the protein-protein interaction challenge
Duncan E. Scott et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Stapling of unprotected helical peptides via photoinduced intramolecular thiol-yne hydrothiolation
Yuan Tian et al.
CHEMICAL SCIENCE (2016)
Hydrocarbon Stapled Peptides as Modulators of Biological Function
Philipp M. Cromm et al.
ACS CHEMICAL BIOLOGY (2015)
A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization
Yuanxiang Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes
Marta Pelay-Gimeno et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories
Robert T. McGibbon et al.
BIOPHYSICAL JOURNAL (2015)
Peptide stapling techniques based on different macrocyclisation chemistries
Yu Heng Lau et al.
CHEMICAL SOCIETY REVIEWS (2015)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Towards understanding cell penetration by stapled peptides
Qian Chu et al.
MEDCHEMCOMM (2015)
New peptide architectures through C-H activation stapling between tryptophan-phenylalanine/tyrosine residues
Lorena Mendive-Tapia et al.
NATURE COMMUNICATIONS (2015)
Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies
Greg H. Bird et al.
ACS CHEMICAL BIOLOGY (2014)
Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides
Yuxiao Wang et al.
ACS CHEMICAL BIOLOGY (2014)
Comparative α-Helicity of Cyclic Pentapeptides in Water
Aline D. de Araujo et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry
Devatha P. Nair et al.
CHEMISTRY OF MATERIALS (2014)
Markov state models of biomolecular conformational dynamics
John D. Chodera et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2014)
Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress
Loren D. Walensky et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Functionalised staple linkages for modulating the cellular activity of stapled peptides
Yu Heng Lau et al.
CHEMICAL SCIENCE (2014)
RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer
Changjie Wu et al.
NATURE COMMUNICATIONS (2014)
Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain
Young Jun Seo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Conserved Cysteine Residues Provide a Protein-Protein Interaction Surface in Dual Oxidase (DUOX) Proteins
Jennifer L. Meitzler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Identification of slow molecular order parameters for Markov model construction
Guillermo Perez-Hernandez et al.
JOURNAL OF CHEMICAL PHYSICS (2013)
Improvements in Markov State Model Construction Reveal Many Non-Native Interactions in the Folding of NTL9
Christian R. Schwantes et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling
Alexander M. Spokoyny et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Effect of hydrocarbon stapling on the properties of α-helical antimicrobial peptides isolated from the venom of hymenoptera
Hubert Chapuis et al.
AMINO ACIDS (2012)
Design of Triazole-Stapled BCL9 α-Helical Peptides to Target the β-Catenin/B-Cell CLL/lymphoma 9 (BCL9) Protein-Protein Interaction
Steven A. Kawamoto et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Rational Design of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors
Avinash Muppidi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Development of α-Helical Calpain Probes by Mimicking a Natural Protein-Protein Interaction
Hyunil Jo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin
Tom N. Grossmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Achieving cell penetration with distance-matching cysteine cross-linkers: a facile route to cell-permeable peptide dual inhibitors of Mdm2/Mdmx
Avinash Muppidi et al.
CHEMICAL COMMUNICATIONS (2011)
Caveolae-dependent Endocytosis Is Required for Class A Macrophage Scavenger Receptor-mediated Apoptosis in Macrophages
Xu-Dong Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Markov models of molecular kinetics: Generation and validation
Jan-Hendrik Prinz et al.
JOURNAL OF CHEMICAL PHYSICS (2011)
Assessing Helical Protein Interfaces for Inhibitor Design
Brooke N. Bullock et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), A PET radiotracer designed for the delineation of histone deacetylase expression in cancer
Brian M. Zeglis et al.
NUCLEAR MEDICINE AND BIOLOGY (2011)
A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53
Federico Bernal et al.
CANCER CELL (2010)
The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
Yingzi Wang et al.
SCIENCE (2010)
Targeting protein-protein interactions for therapeutic intervention: a challenge for the future
Giovanna Zinzalla et al.
FUTURE MEDICINAL CHEMISTRY (2009)
Assessment of helical interfaces in protein-protein interactions
Andrea L. Jochim et al.
MOLECULAR BIOSYSTEMS (2009)
Evaluation of 6-([18F]fluoroacetamido)-1-hexanoicanilide for PET imaging of histone deacetylase in the baboon brain
Alicia E. Reid et al.
NUCLEAR MEDICINE AND BIOLOGY (2009)
A cell-penetrating helical peptide as a potential HIV-1 inhibitor
Hongtao Zhang et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide
Federico Bernal et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Expression of β-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis
L. Ysebaert et al.
LEUKEMIA (2006)
Using circular dichroism spectra to estimate protein secondary structure
Norma J. Greenfield
NATURE PROTOCOLS (2006)
Lysosomal trafficking of β-catenin induced by the tea polyphenol epigallocatechin-3-gallate
WM Dashwood et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)
Cationic TAT peptide transduction domain enters cells by macropinocytosis (vol 102, pg 247, 2005)
IM Kaplan et al.
JOURNAL OF CONTROLLED RELEASE (2005)
A peptide inhibitor of HIV-1 assembly in vitro
J Sticht et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Protein-protein interactions in human disease
DP Ryan et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2005)
Cell-penetrating peptides: tools for intracellular delivery of therapeutics
S Deshayes et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2005)
Cationic TAT peptide transduction domain enters cells by macropinocytosis
IM Kaplan et al.
JOURNAL OF CONTROLLED RELEASE (2005)
Synthesis of constrained helical peptides by thioether ligation: application to analogs of gp41
FM Brunel et al.
CHEMICAL COMMUNICATIONS (2005)
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
LD Walensky et al.
SCIENCE (2004)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
AM Leduc et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and validation
A Jakalian et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2002)
Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat
M Silhol et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides
CE Schafmeister et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Photo-control of helix content in a short peptide
JR Kumita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
