4.4 Article

Neurological manifestations found in children with multisystem inflammatory syndrome

Journal

EXPERIMENTAL AND THERAPEUTIC MEDICINE
Volume 23, Issue 4, Pages -

Publisher

SPANDIDOS PUBL LTD
DOI: 10.3892/etm.2022.11187

Keywords

multisystem inflammatory syndrome in children; SARS-COV2; coronavirus infection; pediatrics

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Multisystem inflammatory syndrome in children (MIS-C) is a disease that can occur in children after SARS-CoV-2 infection, characterized by neurological symptoms. This study examined 30 cases of children with MIS-C in terms of symptoms, laboratory tests, and disease progression, and treatment was administered according to the MIS-C protocol. The patients showed improvement in their condition, and symptoms remitted within days to weeks.
The pandemic that resulted from the spread of SARS-CoV-2 viral infections has affected the population worldwide but has characteristically shown a preponderance for affecting adults. However, cases of SARS-CoV-2 infection have been reported in children, showing a systemic echo and severe damage. Multisystem inflammatory syndrome in children (MIS-C) can occur, on average, 4 weeks after the infection of a child with SARS-CoV-2. The aim of the present study was to examine 30 cases of children affected by MIS-C in terms of symptoms, laboratory tests, and evolution. Patients included in the study presented with neurological symptomatology including headache, meningism, and drowsiness. Treatment was administered in concordance with the protocol for MIS-C. The evolution of the patients in the present study was favorable and the symptomatology remitted in days to weeks. The importance of identifying the features of this disease, its treatment, and that the most probable evolution is favorable is significant in the medical world, especially as the pandemic is ongoing.

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