Journal
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
Volume 14, Issue 2, Pages -Publisher
WILEY
DOI: 10.1002/wnan.1769
Keywords
antibacterial; antifungal; antiviral; catalytic therapy; nanozymes
Funding
- CAS Engineering Laboratory for Nanozymes, Institute of Biophysics, Chinese Academy of Sciences, China
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Nanozymes are nanomaterials with enzyme-like characteristics that provide alternative approaches for enzymatic catalysis. They have advantages of simple preparation, good stability, and low cost, making them promising for applications in antimicrobial infection treatment. Studies have shown that nanozymes are effective in killing pathogenic bacteria, fungi, and viruses, and have great curative effects for diseases caused by these pathogens.
Nanozymes are nanomaterials with enzyme-like characteristics, which catalyze the conversion of enzyme substrates and follow enzymatic kinetics under physiological conditions. As a new generation of artificial enzymes, nanozymes provide alternative approaches for those upon enzymatic catalysis. Compared with natural enzymes, nanozymes have the advantages of simple preparation, good stability and low cost, which makes nanozymes promising for application in many fields, such as antimicrobial infection treatment. Many studies have reported that nanozymes are capable of killing a number of pathogenic bacteria with resistance, fungi as well as viruses, and have shown great curative effects for diseases caused by these pathogens. Herein, we summarize the application of nanozymes for antibacterial, antiviral, and antifungal therapies and outline the issues needing resolution in the future. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease
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