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COVID-19 in pregnancy: implications for fetal brain development

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Maternal immune activation induced by lipopolysaccharide triggers immune It response in pregnant mother and fetus, and induces behavioral impairment Cheek fat in adult rats

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JOURNAL OF PSYCHIATRIC RESEARCH (2018)

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Maternal IL-6 during pregnancy can be estimated from newborn brain connectivity and predicts future working memory in offspring

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Complement: The Emerging Architect of the Developing Brain

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TRENDS IN NEUROSCIENCES (2018)

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Microglia and Beyond: Innate Immune Cells As Regulators of Brain Development and Behavioral Function

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Maternal Immune Activation and Neuropsychiatric Illness: A Translational Research Perspective

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Increasing Role of Maternal Immune Activation in Neurodevelopmental Disorders

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Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring

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BRAIN BEHAVIOR AND IMMUNITY (2017)

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Maternal Immune Activation and Autism Spectrum Disorder: From Rodents to Nonhuman and Human Primates

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Maternal infection during pregnancy and risk of autism spectrum disorders: A systematic review and meta-analysis

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Maternal Immune Activation Disrupts Dopamine System in the Offspring

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The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

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Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders

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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

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Maternal Infection During Pregnancy and Autism Spectrum Disorders

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JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2015)

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Elevated Maternal C-Reactive Protein and Increased Risk of Schizophrenia in a National Birth Cohort

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AMERICAN JOURNAL OF PSYCHIATRY (2014)

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Activation of the Maternal Immune System During Pregnancy Alters Behavioral Development of Rhesus Monkey Offspring

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The risk for behavioural deficits is determined by the maternal immune response to prenatal immune challenge in a neurodevelopmental model

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BRAIN BEHAVIOR AND IMMUNITY (2014)

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Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia

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The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

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Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response

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BRAIN BEHAVIOR AND IMMUNITY (2012)

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Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

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BRAIN BEHAVIOR AND IMMUNITY (2012)

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Article Multidisciplinary Sciences

Modeling an autism risk factor in mice leads to permanent immune dysregulation

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A transient placental source of serotonin for the fetal forebrain

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FETAL, MATERNAL, AND PLACENTAL SOURCES OF SEROTONIN AND NEW IMPLICATIONS FOR DEVELOPMENTAL PROGRAMMING OF THE BRAIN

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Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

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SCIENCE (2011)

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Maternal immune activation alters nonspatial information processing in the hippocampus of the adult offspring

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BRAIN BEHAVIOR AND IMMUNITY (2010)

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Effects of prenatal infection on brain development and behavior: A review of findings from animal models

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Changes in Melanocortin Expression and Inflammatory Pathways in Fetal Offspring of Nonhuman Primates Fed a High-Fat Diet

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ENDOCRINOLOGY (2010)

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IL-1 Receptor Antagonist Protects against Placental and Neurodevelopmental Defects Induced by Maternal Inflammation

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JOURNAL OF IMMUNOLOGY (2010)

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Late Prenatal Immune Activation in Mice Leads to Behavioral and Neurochemical Abnormalities Relevant to the Negative Symptoms of Schizophrenia

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NEUROPSYCHOPHARMACOLOGY (2010)

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Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

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SCIENCE (2010)

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Immune involvement in schizophrenia and autism: Etiology, pathology and animal models

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BEHAVIOURAL BRAIN RESEARCH (2009)

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Neuropathogenesis of Congenital Cytomegalovirus Infection: Disease Mechanisms and Prospects for Intervention

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Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice

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BRAIN BEHAVIOR AND IMMUNITY (2008)

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Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy

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NEUROSCIENCE (2008)

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Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling

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Article Neurosciences

Maternal immune activation alters fetal brain development through interleukin-6

Stephen E. P. Smith et al.

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Serotonin modulates the response of embryonic thalamocortical axons to netrin-1

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NATURE NEUROSCIENCE (2007)

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Article Clinical Neurology

Apoptosis and microglial activation in influenza encephalopathy

Y Nakai et al.

ACTA NEUROPATHOLOGICA (2003)

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Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring

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