Journal
TRENDS IN FOOD SCIENCE & TECHNOLOGY
Volume 119, Issue -, Pages 412-427Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tifs.2021.12.012
Keywords
Vitamin K; Clotting factors; VK dependent Proteins; Coagulation; Prothrombin time; Warfarin; Comorbidities
Categories
Funding
- Science and Engineering Research Board (SERB) -Department of Science and Technology (DST) [IRR/2018/000025]
- Government of India
Ask authors/readers for more resources
This review discusses the deficiency of vitamin K and its potential health impacts, highlighting the challenges in diagnosis and molecular physiology from a nutrigenomics perspective. It also mentions the use of foodomics technologies to study vitamin K deficiency and its effects on human health.
Background: Vitamins play an essential role in various physiological and biological processes, and their deficiency causes several health consequences in humans. Unlike vitamins A, B, C, D, E, the vitamin K (VK) deficiency is not dealt with profusely keeping in view of its inherent dietary sources and its health implications in human physiology such as blood coagulation. The VK family belongs to a variety of distinct subtypes in the length of side chains composed of isoprenoid families, and is important for various biological functions while much of the behaviour is not unknown. Scope and approach: In the recent past, a lot of knowledge has been derived from the VK deficiency and its comorbidities. This review emphasizes on the nutrigenomics perspective of VK deficiency as we throw light on diagnostic challenges of VK. Key findings and conclusions: We highlight the molecular physiological perspectives of VK using systems/nutrigenomics approaches and explore the human health effects of VK deficiency besides giving a gist of foodomics technologies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available