Related references
Note: Only part of the references are listed.Ectonucleoside triphosphate diphosphohydrolases and ecto-5′-nucleotidase in purinergic signaling: how the field developed and where we are now
Herbert Zimmermann
PURINERGIC SIGNALLING (2021)
History of ectonucleotidases and their role in purinergic signaling
Herbert Zimmermann
BIOCHEMICAL PHARMACOLOGY (2021)
CD73 Maintains Hepatocyte Metabolic Integrity and Mouse Liver Homeostasis in a Sex-Dependent Manner
Karel P. Alcedo et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2021)
CD73 or CD39 Deletion Reveals Different Mechanisms of Formation for Spontaneous and Mechanically Stimulated Adenosine and Sex Specific Compensations in ATP Degradation
Ying Wang et al.
ACS CHEMICAL NEUROSCIENCE (2020)
The circular RNA NT5E promotes non-small cell lung cancer cell growth via sponging microRNA-134
Lingyun Dong et al.
AGING-US (2020)
CD73 Promotes Age-Dependent Accretion of Atherosclerosis
Nadia R. Sutton et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2020)
MicroRNA-30a suppresses self-renewal and tumorigenicity of glioma stem cells by blocking the NT5E-dependent Akt signaling pathway
Lilei Peng et al.
FASEB JOURNAL (2020)
CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment
Shi Yong Neo et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes
Sanjay Bhattarai et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
Sangeeta Goswami et al.
NATURE MEDICINE (2020)
CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint
Miao Yu et al.
NATURE COMMUNICATIONS (2020)
Dysregulation of FOXO1 (Forkhead Box O1 Protein) Drives Calcification in Arterial Calcification due to Deficiency of CD73 and Is Present in Peripheral Artery Disease
William J. Moorhead et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2020)
Radiolabeled Human Monoclonal Antibody 067-213 has the Potential for Noninvasive Quantification of CD73 Expression
Hitomi Sudo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73
Joel W. Beatty et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Sex-associated molecular differences for cancer immunotherapy
Youqiong Ye et al.
NATURE COMMUNICATIONS (2020)
Different subpopulations of kidney interstitial cells produce erythropoietin and factors supporting tissue oxygenation in response to hypoxia in vivo
Katharina A. E. Broeker et al.
KIDNEY INTERNATIONAL (2020)
Construction of a human cell landscape at single-cell level
Xiaoping Han et al.
NATURE (2020)
Targeting CD73 to augment cancer immunotherapy
Meejeon Roh et al.
CURRENT OPINION IN PHARMACOLOGY (2020)
Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor
Nami Kitajima et al.
ELIFE (2020)
Discovery of AB680: A Potent and Selective Inhibitor of CD73
Kenneth Lawson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
A Quantitative Proteome Map of the Human Body
Lihua Jiang et al.
CELL (2020)
Structural cells are key regulators of organ-specific immune responses
Thomas Krausgruber et al.
NATURE (2020)
The adenosine pathway in immuno-oncology
Bertrand Allard et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
Impaired estrogen signaling underlies regulatory T cell loss-of-function in the chronically inflamed intestine
Wendy A. Goodman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy
Lukas F. Mager et al.
SCIENCE (2020)
Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production
Xiaohui Du et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
Rui Jin et al.
MOLECULAR CANCER THERAPEUTICS (2020)
Therapeutic effects of adenosine in high flow 21% oxygen aereosol in patients with Covid19-pneumonia
Pierpaolo Correale et al.
PLOS ONE (2020)
Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling
Denis Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Fluorescent Probes for Ecto-5′-nucleotidase (CD73)
Constanze C. Schmies et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Liver dysfunction is associated with poor prognosis in patients after immune checkpoint inhibitor therapy
Keisuke Yokohama et al.
SCIENTIFIC REPORTS (2020)
A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms
James E. Stefano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
CD73 (Cluster of Differentiation 73) and the Differences Between Mice and Humans
Pouya Joolharzadeh et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
The distinct role of CD73 in the progression of pancreatic cancer
Liangjing Zhou et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2019)
Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
Kenneth A. Jacobson et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Physiology and effects of nucleosides in mice lacking all four adenosine receptors
Cuiying Xiao et al.
PLOS BIOLOGY (2019)
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
Nicolas Severe et al.
CELL STEM CELL (2019)
Generation and Function of Non-cell-bound CD73 in Inflammation
Enja Schneider et al.
FRONTIERS IN IMMUNOLOGY (2019)
Cell type- and tissue-specific functions of ecto-5′-nucleotidase (CD73)
Marquet Minor et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)
Estrogen receptors modulate ectonucleotidases activity in hippocampal synaptosomes of male rats
Natasa Mitrovic et al.
NEUROSCIENCE LETTERS (2019)
Cell-type-specific CD73 expression is an independent prognostic factor in bladder cancer
Maarit K. Koivisto et al.
CARCINOGENESIS (2019)
Adenosine Metabolism: Emerging Concepts for Cancer Therapy
Detlev Boison et al.
CANCER CELL (2019)
Spatial sorting enables comprehensive characterization of liver zonation
Shani Ben-Moshe et al.
NATURE METABOLISM (2019)
Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma
Karel P. Alcedo et al.
HEPATOLOGY COMMUNICATIONS (2019)
CircNT5E Acts as a Sponge of miR-422a to Promote Glioblastoma Tumorigenesis
Renjie Wang et al.
CANCER RESEARCH (2018)
In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche
Martin Breitbach et al.
CELL STEM CELL (2018)
Characterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors
Eleonora De Martin et al.
JOURNAL OF HEPATOLOGY (2018)
The Hypoxia-Adenosine Link during Intestinal Inflammation
Jessica L. Bowser et al.
JOURNAL OF IMMUNOLOGY (2018)
Cancer immunotherapy efficacy and patients' sex: a systematic review and meta-analysis
Fabio Conforti et al.
LANCET ONCOLOGY (2018)
PHARMACOLOGY OF ADENOSINE RECEPTORS: THE STATE OF THE ART
Pier Andrea Borea et al.
PHYSIOLOGICAL REVIEWS (2018)
Who Is Who in Adenosine Transport
Marcal Pastor-Anglada et al.
FRONTIERS IN PHARMACOLOGY (2018)
Controlling the Immune Suppressor: Transcription Factors and MicroRnAs Regulating CD73/NT5E
Theresa Kordass et al.
FRONTIERS IN IMMUNOLOGY (2018)
Spatial Reconstruction of Single Enterocytes Uncovers Broad Zonation along the Intestinal Villus Axis
Andreas E. Moor et al.
CELL (2018)
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
Jie Lan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Multiple steps determine CD73 shedding from RPE: lipid raft localization, ARA1 interaction, and MMP-9 up-regulation
Wei Zhang et al.
PURINERGIC SIGNALLING (2018)
A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment
Arabella Young et al.
CANCER RESEARCH (2018)
Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection
Sun-sang J. Sung et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Calcification of joints and arteries with novel NT5E mutations with involvement of upper extremity arteries
Kenji Yoshioka et al.
VASCULAR MEDICINE (2017)
Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation
Yiming Xu et al.
NATURE COMMUNICATIONS (2017)
Low expression of CD39 and CD73 genes in centenarians compared with octogenarians
Almudena Crooke et al.
IMMUNITY & AGEING (2017)
CD39/CD73 upregulation on myeloid-derived suppressor cells via TGF--mTOR-HIF-1 signaling in patients with non-small cell lung cancer
Jieyao Li et al.
ONCOIMMUNOLOGY (2017)
Intestinal Epithelial Ecto-5′-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella
Daniel J. Kao et al.
INFECTION AND IMMUNITY (2017)
MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
Julia Reinhardt et al.
CANCER RESEARCH (2017)
Loss of CD73-mediated actin polymerization promotes endometrial tumor progression
Jessica L. Bowser et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
17β-ESTRADIOL UPREGULATES ECTO-5′-NUCLEOTIDASE (CD73) IN HIPPOCAMPAL SYNAPTOSOMES OF FEMALE RATS THROUGH ACTION MEDIATED BY ESTROGEN RECEPTOR-α AND -β
N. Mitrovic et al.
NEUROSCIENCE (2016)
Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC
Hui Jin et al.
SCIENCE SIGNALING (2016)
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
Pier Andrea Borea et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC
Hui Jin et al.
SCIENCE SIGNALING (2016)
Homeostasis, Inflammation, and Disease Susceptibility
Maya E. Kotas et al.
CELL (2015)
CD73 Predicts Favorable Prognosis in Patients with Nonmuscle-Invasive Urothelial Bladder Cancer
Marian S. Wettstein et al.
DISEASE MARKERS (2015)
Calcification of joints and arteries: second report with novel NT5E mutations and expansion of the phenotype
Zeng Zhang et al.
JOURNAL OF HUMAN GENETICS (2015)
Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver
Bruce Wang et al.
NATURE (2015)
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection
Stephen M. Hatfield et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2014)
Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5′-nucleotidase (CD73)
Natasha T. Snider et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
CD73 (Ecto-5′-Nucleotidase) Hepatocyte Levels Differ Across Mouse Strains and Contribute to Mallory-Denk Body Formation
Natasha T. Snider et al.
HEPATOLOGY (2013)
Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors
Paul A. Beavis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Purinergic signalling and cancer
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2013)
Activated hepatic stellate cells upregulate transcription of ecto-5′-nucleotidase/CD73 via specific SP1 and SMAD promoter elements
Michel Fausther et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors
Jingsheng Xia et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling
Karen Knapp et al.
STRUCTURE (2012)
The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway
Akio Ohta et al.
FRONTIERS IN IMMUNOLOGY (2012)
CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis
John Stagg et al.
CANCER RESEARCH (2011)
Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
Sergey Ryzhov et al.
JOURNAL OF IMMUNOLOGY (2011)
NT5E Mutations and Arterial Calcifications
Cynthia St Hilaire et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Extracellular adenosine triphosphate and adenosine in cancer
J. Stagg et al.
ONCOGENE (2010)
Basal Release of ATP: An Autocrine-Paracrine Mechanism for Cell Regulation
Ross Corriden et al.
SCIENCE SIGNALING (2010)
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
Akio Ohta et al.
JOURNAL OF IMMUNOLOGY (2009)
Extracellular Adenosine Production by Ecto-5′-Nucleotidase Protects During Murine Hepatic Ischemic Preconditioning
Melanie L. Hart et al.
GASTROENTEROLOGY (2008)
Dynamics of shear-induced ATP release from red blood cells
Jiandi Wan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Adenosine, an endogenous distress signal, modulates tissue damage and repair
B. B. Fredholm
CELL DEATH AND DIFFERENTIATION (2007)
Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury
Tobias Eckle et al.
JOURNAL OF IMMUNOLOGY (2007)
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
Silvia Deaglio et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Cardioprotection by ecto-5′-nucleotidase (CD73) and A2B adenosine receptors
Tobias Eckle et al.
CIRCULATION (2007)
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation
Joseph Khoury et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Extracellular adenosine activates AMP-dependent protein kinase (AMPK)
I Aymerich et al.
JOURNAL OF CELL SCIENCE (2006)
A2A adenosine receptor induction inhibits IFN-γ production in murine CD4+ T cells
CM Lappas et al.
JOURNAL OF IMMUNOLOGY (2005)
Crucial role for ecto-5-′nucleotidase (CD73) in vascular leakage during hypoxia
LF Thompson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Adenosine: an endogenous regulator of innate immunity
G Hasko et al.
TRENDS IN IMMUNOLOGY (2004)
Mammalian 5′-nucleotidases
V Bianchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes
SM Joseph et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The concept of allostasis in biology and biomedicine
BS McEwen et al.
HORMONES AND BEHAVIOR (2003)
Evidence that release of adenosine triphosphate from endothelial cells during increased shear stress is vesicular
P Bodin et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2001)
Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia
L Homolya et al.
JOURNAL OF CELL BIOLOGY (2000)
Share Paper
