Antibacterial activity and biocompatibility of Ag-coated Ti implants: importance of surface modification parameters

Surface modification of titanium (Ti) implants to meet both antibacterial and biocompatibility requirements is of prime significance since it can almost guarantee implantation success. This contribution attempts to modify the surface of Ti by an integrated three-step treatment, including chemical etching, silanisation, and deposition of a silver nanoparticles (Ag NPs)-containing layer. The morphological characteristics, antibacterial activity, and biocompatibility of the modified Ti were evaluated as a function of etching time, silanisation time, and solvent type. The results illustrated the importance of the surface modification parameters in attaining favourable antibacterial performance and biocompatibility. The Ag-coated Ti substrate which underwent 2 h etching followed by 2 h silanisation in an ethanol solvent suggested the highest antibacterial activity and biocompatibility. It is believed that the application of an appropriate surface modification approach allows new ways to produce Ti implants for medical applications.

Automated summary

The surface modification of titanium implants is crucial for both antibacterial properties and biocompatibility. The study demonstrated the importance of surface modification parameters in achieving favorable antibacterial performance and biocompatibility. The optimal approach was found to be using ethanol solvent for 2 hours etching followed by 2 hours silanisation.