Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 143, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2021.116406
Keywords
Forensic science; Crime scene investigation; Paper-based devices; Microfluidics; Illicit drugs; Explosives; Gunshot residues (GSR); New psychoactive substances (NPS); DNA; Biosensor
Categories
Funding
- Fondazione Cariverona [CUP B36J16002570003]
- Ministry of Science and Higher Education of the Russian Federation [07515-2020-926]
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The use of paper-based microfluidics devices (mPADs) has grown rapidly in recent years, especially in the field of forensic science. These devices provide a rapid response on-site, offering advantages in evidence collection and preservation. The technology shows promise for future developments in this area.
The use of paper-based microfluidics devices (mPADs) for designing rapid, easy, and on-site devices has undergone a dramatic increase in the last few years and the development of applications in the field of forensic science has had concomitant advances. The use of mPADs at the crime scene is finalized not only to obtain a rapid response but also to have crucial information on evidence collection. Several authors have proposed mPADs as alternative approaches to existing tests. These devices are designed to be used on-site without, or minimal, power sources. Furthermore, the technology provides prompt-readouts using a small sample volume, preserving important evidence for instrumental analysis. This review aims to provide a critical evaluation of developed mPADs. The document includes a brief overview on fabrication methods and on detection strategies, and it assesses advantages and limitations of applications related to forensic matters. A final section is devoted to future developments. (C) 2021 Elsevier B.V. All rights reserved.
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