4.6 Article

Editor: Lawrence Lash Keywords: Cigarette smoke Epithelial-mesenchymal transition Prostate Exosomes Circ_0001359 Collagen deposition

Related references

Note: Only part of the references are listed.
Article Cell Biology

Primary cilia presence and implications in bladder cancer progression and invasiveness

Pablo Iruzubieta et al.

Summary: Research on urothelial bladder cancer found a clear correlation between epithelial-to-mesenchymal transition, Hedgehog activation, cancer stage, and progression. Furthermore, the presence of primary cilia in NMIBC suggests a potential role in tumoral migration and invasiveness.

HISTOCHEMISTRY AND CELL BIOLOGY (2021)

Article Pharmacology & Pharmacy

The exosome-like vesicles derived from androgen exposed-prostate stromal cells promote epithelial cells proliferation and epithelial-mesenchymal transition

Jinglou Chen et al.

Summary: The study highlighted the impact of prostatic stromal cell-derived exosomes on the phenotype changes and collagen deposition of prostate epithelial cells, providing insights into a potential mechanism in benign prostatic hyperplasia.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2021)

Review Biochemistry & Molecular Biology

Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT

Margherita Sisto et al.

Summary: Recent advances in understanding the molecular pathways linking inflammation with organ fibrosis and autoimmune diseases have identified EMT as a common association. The chronic inflammatory microenvironment plays a crucial role in inducing pathological EMT, with TGF-beta being a key player in fibrosis induction. Further research aims to target EMT-dependent fibrosis in autoimmune diseases through a better understanding of molecular responses to inflammatory signals.

BIOMOLECULES (2021)

Article Environmental Sciences

Ubiquitous atmospheric contamination by tobacco smoke: Nicotine and a new marker for tobacco smoke-derived particulate matter, nicotelline

Noel J. Aquilina et al.

Summary: This study proposes nicotelline as a better marker for Second Hand Smoke (SHS) in particulate matter (PM) compared to nicotine. The presence of nicotelline in outdoor air samples collected in different countries suggests its wide distribution. While the fraction of outdoor airborne PM derived from SHS is estimated to be low, nicotelline could still be useful in tracing the presence of SHS and other harmful components in polluted environments.

ENVIRONMENT INTERNATIONAL (2021)

Review Physiology

THE FGF/FGFR SYSTEM IN THE PHYSIOPATHOLOGY OF THE PROSTATE GLAND

Arianna Giacomini et al.

Summary: Fibroblast growth factors (FGFs) are a family of proteins that play a role in various biological processes, from embryonic development to cancer. They are important in the physiopathology of the prostate gland, ranging from embryonic development to modulation of neoplastic transformation.

PHYSIOLOGICAL REVIEWS (2021)

Review Biochemical Research Methods

Circular RNAs as microRNA sponges: evidence and controversies

Morten T. Jarlstad Olesen et al.

Summary: Gene expression in eukaryotic cells is a complex process regulated at transcriptional and post-transcriptional levels. miRs and circRNAs play key roles at the post-transcriptional level, with circRNAs acting as sponges for miRs to increase the expression of corresponding target genes.

NON-CODING GENOME (2021)

Review Chemistry, Medicinal

Small molecule inhibitors of epithelial-mesenchymal transition for the treatment of cancer and fibrosis

Ya-Long Feng et al.

MEDICINAL RESEARCH REVIEWS (2020)

Review Multidisciplinary Sciences

The biology, function, and biomedical applications of exosomes

Raghu Kalluri et al.

SCIENCE (2020)

Review Biotechnology & Applied Microbiology

Adipogenesis Regulation and Endocrine Disruptors: Emerging Insights in Obesity

Jorge Enrique Gonzalez-Casanova et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Review Biochemistry & Molecular Biology

New Insights into the Role of Epithelial-Mesenchymal Transition during Aging

Francisco Santos et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Environmental Sciences

Sex hormones and oxidative stress mediated phthalate-induced effects in prostatic enlargement

Wei-Hsiang Chang et al.

ENVIRONMENT INTERNATIONAL (2019)

Review Geriatrics & Gerontology

Pathophysiology of Benign Prostatic Hyperplasia and Benign Prostatic Enlargement: A Mini-Review

Stephan Madersbacher et al.

GERONTOLOGY (2019)

Review Biochemistry & Molecular Biology

TGF--Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis

Yang Hao et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Biochemistry & Molecular Biology

Exosomes in Systemic Sclerosis: Messengers Between Immune, Vascular and Fibrotic Components?

Marta Colletti et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Genetics & Heredity

The biogenesis, biology and characterization of circular RNAs

Lasse S. Kristensen et al.

NATURE REVIEWS GENETICS (2019)

Article Medicine, Research & Experimental

miR-582-3p and miR-582-5p Suppress Prostate Cancer Metastasis to Bone by Repressing TGF-β Signaling

Shuai Huang et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2019)

Review Pharmacology & Pharmacy

Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium

Jessica N. Blom et al.

PHARMACOLOGY & THERAPEUTICS (2018)

Article Environmental Sciences

Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis

Yi He et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2017)

Article Multidisciplinary Sciences

EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling

Vincent J. Guen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Public, Environmental & Occupational Health

The effects of environmental chemical carcinogens on the microRNA machinery

A. Izzotti et al.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2014)

Review Endocrinology & Metabolism

The endocrine effects of nicotine and cigarette smoke

Jesse Oliver Tweed et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)

Article Physiology

The Ciliary Cytoskeleton

Lotte B. Pedersen et al.

COMPREHENSIVE PHYSIOLOGY (2012)