4.7 Review

Chronic consumption of food-additives lead to changes via microbiota gut-brain axis

Journal

TOXICOLOGY
Volume 464, Issue -, Pages -

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.tox.2021.153001

Keywords

Food additives; Microbiota-brain axis; Gut microbiota; Neurotransmitters; Dysbiosis

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This study reveals a clear link between food additives and changes in the gut microbiota that lead to various chronic diseases, yet research on the effects of food additives on microbiota is still inadequate, indicating a need for further investigation in this area.
Some food additives have demonstrated to induce dysbiosis leading to the development gut and gastrointestinal diseases. In order to clarify how this dysbiosis affects the microbiota gut-brain axis, a systematic interpretative literature review is carried out in this work. This review was made in seven academic search engines using the keywords shown below. The main finding of this work is a clear link between the changes in the gut microbiota promoted by food additives and the causes that lead to many reported diseases related to chronic food additives consumption. Despite the findings, studies on the effects of food additives on microbiota are still insufficient. Therefore, this work should serve as a motivation for future research on this subject.

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