Journal
THROMBOSIS RESEARCH
Volume 207, Issue -, Pages 58-61Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.thromres.2021.09.001
Keywords
Heparin-induced thrombocytopenia (HIT); Pregnancy; First trimester; Fondaparinux; Anticoagulation
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Heparin-induced thrombocytopenia in pregnancy is rare, with varied therapeutic options and durations. This case report discusses a 41-year-old female with HIT during pregnancy and the subsequent clinical management strategies.
Heparin-induced thrombocytopenia in pregnancy is an uncommon phenomenon which rarely occurs in the first trimester. Therapeutic options and duration of therapeutic anticoagulation are varied amongst reported published cases. We report a 41-year-old female with confirmed HIT following anticoagulation with dalteparin for deep vein thrombosis (DVT). She was treated with therapeutic fondaparinux for 3 months followed by prophylaxis dosage until delivery and for 6 weeks thereafter. A review of reported cases of the development of HIT in the first trimester and subsequent clinical management is discussed.
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