4.7 Article

SARS-CoV-2 detection with aptamer-functionalized gold nanoparticles

Related references

Note: Only part of the references are listed.
Article Infectious Diseases

Accuracy of a nucleocapsid protein antigen rapid test in the diagnosis of SARS-CoV-2 infection

Bo Diao et al.

Summary: The FIC assay for NP antigen testing shows high specificity and relatively high sensitivity in early-phase SARS-CoV-2 diagnosis, according to a study conducted in Wuhan and Chongqing between February 10 and 15, 2020.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

Article Chemistry, Analytical

Conventional PCR assisted single-component assembly of spherical nucleic acids for simple colorimetric detection of SARS-CoV-2

Abbas Karami et al.

Summary: A colorimetric strategy based on gold nanoparticle assembly was developed for visual detection of SARS-CoV-2 RNA PCR products, simplifying the testing process and providing clear differentiation between positive and negative cases in post-PCR colorimetric test. The strategy rivals real-time PCR in sensitivity when evaluating samples from laboratory-confirmed cases of SARS-CoV-2 infection.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Article Biophysics

A novel rapid detection for SARS-CoV-2 spike 1 antigens using human angiotensin converting enzyme 2 (ACE2)

Jong-Hwan Lee et al.

Summary: This study presents a novel rapid detection method for the SARS-CoV-2 S1 antigen using a matched pair of ACE2 and antibody. The detection method showed high specificity and sensitivity without cross-reactivity, making it a valuable tool in detecting the S1 antigen from COVID-19 patients.

BIOSENSORS & BIOELECTRONICS (2021)

Article Medical Laboratory Technology

Initial determination of COVID-19 seroprevalence among outpatients and healthcare workers in Minnesota using a novel SARS-CoV-2 total antibody ELISA

Stefani N. Thomas et al.

Summary: The study developed an in-house SARS-CoV-2 total antibody test and evaluated its clinical performance, showing high sensitivity and specificity for detecting COVID-19 antibodies. Results from testing in Minnesota revealed different seroprevalence rates among healthcare workers and outpatients, indicating the potential usefulness of the test in epidemiological studies during the COVID-19 pandemic.

CLINICAL BIOCHEMISTRY (2021)

Article Chemistry, Analytical

Hairpin-Spherical Nucleic Acids for Diagnosing COVID-19: a Simple Method to Generalize the Conventional PCR for Molecular Assays

Abbas Karami et al.

Summary: This study modified the PCR assay with target-responsive assembly of gold nanoparticle-core hairpin-spherical nucleic acids for naked-eye colorimetric detection of SARS-CoV-2 RNA, achieving similar sensitivity to real-time RT-PCR method.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Julia A. Zakashansky et al.

Summary: By utilizing low-cost electrodes and aptamer technology, we can detect the spike protein of SARS-CoV-2 in saliva with a sensitivity down to 1 ag/mL, making it suitable for large-scale viral infection detection.

ANALYTICAL METHODS (2021)

Review Chemistry, Multidisciplinary

Aptamer-Based Biosensors for Environmental Monitoring

Erin M. McConnell et al.

FRONTIERS IN CHEMISTRY (2020)

Letter Virology

A DNA Aptamer Based Method for Detection of SARS-CoV-2 Nucleocapsid Protein

Zhiqiang Chen et al.

VIROLOGICA SINICA (2020)

Article Biochemistry & Molecular Biology

Considerations around the SARS-CoV-2 Spike Protein with Particular Attention to COVID-19 Brain Infection and Neurological Symptoms

Kambiz Hassanzadeh et al.

ACS CHEMICAL NEUROSCIENCE (2020)

Article Chemistry, Analytical

Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein

Yanling Song et al.

ANALYTICAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Point-of-Use Rapid Detection of SARS-CoV-2: Nanotechnology-Enabled Solutions for the COVID-19 Pandemic

Navid Rabiee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Multidisciplinary Sciences

Molecular diagnostic technologies for COVID-19: Limitations and challenges

Adeel Afzal

JOURNAL OF ADVANCED RESEARCH (2020)

Article Pharmacology & Pharmacy

COVID-19 Clinical Diagnostics and Testing Technology

Cindy H. Chau et al.

PHARMACOTHERAPY (2020)

Letter Biotechnology & Applied Microbiology

The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing

Matthew J. MacKay et al.

NATURE BIOTECHNOLOGY (2020)

Review Medicine, Research & Experimental

Applications of gold nanoparticles in virus detection

Mohamed Shehata Draz et al.

THERANOSTICS (2018)

Article Chemistry, Multidisciplinary

Colorimetric Immunosensor by Aggregation of Photochemically Functionalized Gold Nanoparticles

Marzia Iarossi et al.

ACS OMEGA (2018)

Article Chemistry, Multidisciplinary

Discrimination of Proteins Using an Array of Surfactant-Stabilized Gold Nanoparticles

Jacob L. Rogowski et al.

LANGMUIR (2016)

Review Biochemistry & Molecular Biology

Aptamer-nanoparticle complexes as powerful diagnostic and therapeutic tools

Hunho Jo et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2016)

Article Biophysics

Chemical nose for the visual identification of emerging ocular pathogens using gold nanostars

Mohit S. Verma et al.

BIOSENSORS & BIOELECTRONICS (2014)

Article Chemistry, Analytical

Aptamer-gold nanoparticle-based colorimetric assay for the sensitive detection of thrombin

Yi Peng et al.

SENSORS AND ACTUATORS B-CHEMICAL (2013)

Article Chemistry, Multidisciplinary

Adsorption of a Protein Mono layer via Hydrophobic Interactions Prevents Nanoparticle Aggregation under Harsh Environmental Conditions

Sergio Dominguez-Medina et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2013)

Review Chemistry, Multidisciplinary

Gold Nanoparticles in Chemical and Biological Sensing

Krishnendu Saha et al.

CHEMICAL REVIEWS (2012)

Review Chemistry, Analytical

Noble Metal Nanoparticles for Biosensing Applications

Goncalo Doria et al.

SENSORS (2012)

Article Chemistry, Analytical

Aptamer-Conjugated Nanoparticles for Cancer Cell Detection

Colin D. Medley et al.

ANALYTICAL CHEMISTRY (2011)

Article Chemistry, Multidisciplinary

Aptamer-Based SERRS Sensor for Thrombin Detection

Hansang Cho et al.

NANO LETTERS (2008)

Article Chemistry, Multidisciplinary

A gold nanoparticle-based aptamer target binding readout for ATP assay

Jing Wang et al.

ADVANCED MATERIALS (2007)

Article Chemistry, Multidisciplinary

Gold nanoparticle-based competitive colorimetric assay for detection of protein-protein interactions

CS Tsai et al.

CHEMICAL COMMUNICATIONS (2005)

Article Chemistry, Physical

The optical properties of metal nanoparticles: The influence of size, shape, and dielectric environment

KL Kelly et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2003)