4.7 Article

A dual lock-and-key two photon fluorescence probe in response to hydrogen peroxide and viscosity: Application in cellular imaging and inflammation therapy

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Highly Sensitive Near-Infrared Imaging of Peroxynitrite Fluxes in Inflammation Progress

Zhao Wang et al.

Summary: The article presents a highly sensitive NIR fluorescence probe DDAO-PN for in vivo detection of ONOO- in inflammation. The probe demonstrates rapid response and high sensitivity in detecting ONOO-, which has the potential to advance research on inflammation-related diseases.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

A lysosomal polarity-specific two-photon fluorescent probe for visualization of autophagy

Zixiang Yuan et al.

Summary: A polarity-specific fluorescent probe Lyso-NA was synthesized for monitoring autophagy, showing real-time long-term fluorescence visualization of autophagy in living cells. With low toxicity and selective accumulation in lysosomes, this probe is suitable for detecting changes in lysosomal polarity of living cells.

CHINESE CHEMICAL LETTERS (2021)

Article Chemistry, Applied

Highly sensitive and selective water -soluble fluorescent probe for the detection of formaldehyde in leather products

Yansong Wang et al.

Summary: The study proposes a fluorescence-based method for detecting formaldehyde by synthesizing a water-soluble probe FAP-1 and successfully using it for formaldehyde analysis in genuine leather samples. Compared with traditional HPLC and UV-Vis methods, the fluorescence method is more competitive and promising.

DYES AND PIGMENTS (2021)

Article Chemistry, Analytical

A dual-response fluorescent probe for detection and bioimaging of hydrazine and cyanide with different fluorescence signals

Shuai Mu et al.

Summary: A novel dual-response fluorescent probe (RDCN) was designed and synthesized for the detection of hydrazine and cyanide, exhibiting discriminative sensing behaviors with high selectivity and sensitivity. The probe was successfully applied for detection in water samples and visualization in live cells, showing potential applications for discriminative detection in biological environment.

TALANTA (2021)

Article Chemistry, Analytical

Naphthalimide-4-(4-nitrophenyl)thiosemicarbazide: A Fluorescent Probe for Simultaneous Monitoring of Viscosity and Nitric Oxide in Living Cells

Su Jung Kim et al.

Summary: Intracellular viscosity and nitric oxide levels may be related to various pathological conditions, and simultaneous monitoring of them is valuable for studying cellular pathological conditions. A fluorescent chemical probe was successfully synthesized for monitoring alterations in intracellular viscosity and nitric oxide levels in living cells.

ANALYTICAL CHEMISTRY (2021)

Article Spectroscopy

Design, synthesis and application of a dual-functional fluorescent probe for reactive oxygen species and viscosity

Hongyu Li et al.

Summary: The fluorescence probe based on a cyanine fluorophore is designed for determining viscosity and reactive oxygen species. The fluorescence intensity increases with viscosity and shows rapid linear response to OCl- or ONOO-, allowing selective detection. The probe is cell permeable and can detect viscosity and reactive oxygen species in living cells using confocal microscope fluorescence imaging.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

Article Chemistry, Analytical

Observation of inflammation-induced mitophagy during stroke by a mitochondria-targeting two-photon ratiometric probe

Fei Cheng et al.

Summary: This study reports the development of a new, pH-sensitive, mitochondria-targeting two-photon ratiometric probe (Mito-BNO) for real-time tracking of mitophagy, a process that can be accelerated in brain tissue during stroke. Mito-BNO demonstrates excellent capability for mitochondrial localization and can effectively distinguish mitochondria from other subcellular organelles. The study successfully demonstrates the relationship between mitophagy and neuroinflammation during stroke, providing valuable insights for stroke pathogenesis and potential new targets for diagnosis and treatment.

ANALYST (2021)

Review Chemistry, Multidisciplinary

Indicator displacement assays (IDAs): the past, present and future

Adam C. Sedgwick et al.

Summary: Indicator displacement assays (IDAs) offer a unique and innovative approach to molecular sensing, with advantages including low cost, high sensitivity, and high-throughput automation analysis. IDAs can facilitate the detection of a range of biologically/environmentally important species, provide a method for the detection of complex analytes or for the determination and discrimination of unknown sample mixtures. The simplicity and versatility of IDAs have led to their widespread use in molecular sensing, alongside other common approaches such as reaction-based sensors and chemosensors.

CHEMICAL SOCIETY REVIEWS (2021)

Editorial Material Cardiac & Cardiovascular Systems

Hypertension and Mitochondrial Oxidative Stress Revisited Sirtuin 3, the Improved Antioxidant

Francis J. Miller

CIRCULATION RESEARCH (2020)

Article Chemistry, Analytical

Imaging Hg2+-Induced Oxidative Stress by NIR Molecular Probe with Dual-Key-and-Lock Strategy

Xiaopeng Yang et al.

ANALYTICAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

A general strategy to quantify analytes through fluorescence chromaticity and luminosity

Tianyu Liang et al.

CHINESE CHEMICAL LETTERS (2020)

Article Chemistry, Multidisciplinary

An Innovative Hydrogen Peroxide-Sensing Scaffold and Insight Towards its Potential as an ROS-Activated Persulfide Donor

Rynne A. Hankins et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Imaging and Profiling of Proteins under Oxidative Conditions in Cells and Tissues by Hydrogen-Peroxide-Responsive Labeling

Hao Zhu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Multidisciplinary

Development of dual-key-and-lock responsive probes for biosensing and imaging

Huan Feng et al.

NEW JOURNAL OF CHEMISTRY (2020)

Article Materials Science, Biomaterials

A highly sensitive red-emitting probe for the detection of viscosity changes in living cells, zebrafish, and human blood samples

Manlin Fu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Article Biochemistry & Molecular Biology

Effects of sulfane sulfur content in benzyl polysulfides on thiol-triggered H2S release and cell proliferation

Sarah G. Bolton et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Article Chemistry, Multidisciplinary

Dual-Key-and-Lock Ruthenium Complex Probe for Lysosomal Formaldehyde in Cancer Cells and Tumors

Chaolong Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Review Chemistry, Multidisciplinary

Development and Application of Carbonyl Sulfide-Based Donors for H2S Delivery

Carolyn M. Levinn et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Article Chemistry, Multidisciplinary

Ferroptosis Accompanied by •OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe

Hongyu Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

Colorimetric Carbonyl Sulfide (COS)/Hydrogen Sulfide (H2S) Donation from gamma-Ketothiocarbamate Donor Motifs

Yu Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

New Autoinductive Cascade for the Optical Sensing of Fluoride: Application in the Detection of Phosphoryl Fluoride Nerve Agents

Xiaolong Sung et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Review Chemistry, Multidisciplinary

Fluorescent chemosensors: the past, present and future

Di Wu et al.

CHEMICAL SOCIETY REVIEWS (2017)

Article Chemistry, Analytical

In vivo near-infrared fluorescence imaging of amyloid-β plaques with a dicyanoisophorone-based probe

Jia-ying Zhu et al.

ANALYTICA CHIMICA ACTA (2017)

Review Pharmacology & Pharmacy

Using hydrogen sulfide to design and develop drugs

Vincenzo Calderone et al.

EXPERT OPINION ON DRUG DISCOVERY (2016)

Review Chemistry, Multidisciplinary

Fluorescent Probes for Sensing and Imaging within Specific Cellular Organelles

Hao Zhu et al.

ACCOUNTS OF CHEMICAL RESEARCH (2016)

Article Chemistry, Multidisciplinary

Self-Immolative Thiocarbamates Provide Access to Triggered H2S Donors and Analyte Replacement Fluorescent Probes

Andrea K. Steiger et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Biochemistry & Molecular Biology

H2S Is an Endothelium-Derived Hyperpolarizing Factor

Guanghua Tang et al.

ANTIOXIDANTS & REDOX SIGNALING (2013)

Article Multidisciplinary Sciences

A physical explanation of the temperature dependence of physiological processes mediated by cilia and flagella

Stuart Humphries

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Chemistry, Multidisciplinary

Fluorescence Ratiometry and Fluorescence Lifetime Imaging: Using a Single Molecular Sensor for Dual Mode Imaging of Cellular Viscosity

Xiaojun Peng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Chemistry, Multidisciplinary

Molecular rotor measures viscosity of live cells via fluorescence lifetime imaging

Marina K. Kuimova et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Review Biochemistry & Molecular Biology

Mitochondrial dysfunction in cardiovascular disease

SW Ballinger

FREE RADICAL BIOLOGY AND MEDICINE (2005)