Integrative approaches in genome structure analysis

New technological advances in integrated imaging, sequencing-based assays, and computational analysis have revolutionized our view of genomes in terms of their structure and dynamics in space and time. These advances promise a deeper understanding of genome functions and mechanistic insights into how the nucleus is spatially organized and functions. These wide arrays of complementary data provide an opportunity to produce quantitative integrative models of nuclear organization. In this article, we highlight recent key developments and discuss the outlook for these fields.

Automated summary

Advancements in technology have allowed us to have a better understanding of the structure and dynamics of genomes. These developments have enabled the creation of quantitative models of nuclear organization, leading to deeper insights into genome functions and spatial organization.