Journal
STEM CELL RESEARCH
Volume 60, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.scr.2022.102718
Keywords
-
Funding
- National Natural Science Foundation of China [81870902, 81801248]
- Joint Funds for the Innovation of Science and Technology of Fujian province [2018Y9082]
- Youth Scientific Research Project of Fujian Provincial Health Commission [2020QNA045]
Ask authors/readers for more resources
In this study, an induced pluripotent stem cell line was generated from a DMD patient's dermal fibroblasts using non-integrating Sendai virus. This iPSC line exhibited normal iPSC characteristics and could differentiate into the three germ layers.
Duchenne muscular dystrophy (DMD) is an X-linked recessive degenerative disease characterized by progressive weakness of limbs. In this study, we generated an induced pluripotent stem cell line from a DMD patient's dermal fibroblasts with non-integrating Sendai virus. The patient carried a rare c.4518 + 512 T > A variant in the DMD gene. This iPSC line displayed normal iPSC morphology, karyotypes and pluripotency expression markers, and also can be differentiated into the three germ layers.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
