Journal
SOUTH AFRICAN JOURNAL OF BOTANY
Volume 149, Issue -, Pages 899-915Publisher
ELSEVIER
DOI: 10.1016/j.sajb.2021.10.004
Keywords
Phytochemistry; Indian mangroves; Natural products; Biological activity; Metabolites
Categories
Funding
- Ministry of Environment, Forest and Climate Change, Government of India
- World Bank under the ICZM project [P097985]
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The mangrove ecosystem has been extensively studied, resulting in the discovery of bioactive compounds with anticancer, antiulcer, antioxidant, antidiabetic, and antimicrobial properties. There are 46 mangrove species in India, and 36 of them are used in traditional medicine. A total of 249 bioactive compounds have been isolated from 18 species.
The mangrove ecosystem is being intensively studied with the hope of discovering new chemical entities with biomedical potentials. A number of biologically active compounds with varying degrees of action such as anticancer, antiulcer, antioxidant, antidiabetic and antimicrobial properties have been isolated from mangroves. Totally 81 mangrove species have been reported worldwide, of which 46 species are reported to occur in India. Among these, around 36 mangrove species are used in traditional medicine. Approximately 249 bioactive compounds have been isolated from 18 species, and the remaining species are yet to be screened. Biologically active compounds such as limonoids, terpenoids, alkaloids, glycosides, steroids, flavonoids, esters, quinones, phenols, acids, aliphatic alcohol, amides, lactones, aliphatic ketones, and benzodioxols have been derived from the leaves, stems, barks, fruits, and seeds of Indian mangrove plants. This review examines the current trends in the screening and biological activity of metabolites from the Indian mangroves. This comprehensive review in turn can serve as a potential resource for future drug development endeavours. (C) 2021 SAAB. Published by Elsevier B.V. All rights reserved.
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