Journal
SOFT MATTER
Volume 18, Issue 5, Pages 938-942Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1sm01792f
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Funding
- Science and Engineering Research Board, Government of India [CRG/2018/000555]
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This study investigates the changes in the excited state intramolecular proton transfer (ESIPT) of 3-HF caused by cationic surfactant-induced compaction of DNA.
3-Hydroxyflavone (3-HF), which binds to the minor groove of DNA, is a strong antioxidant and hence a potent therapeutic and diagnostic agent. A special photo-property, called excited state intramolecular proton transfer (ESIPT), makes the 3-HF derivatives sensitive to the cellular hydrophobic microenvironment. The present study depicts the various changes in the ESIPT of 3-HF due to cationic surfactant-induced compaction of DNA.
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