4.1 Article

High-Risk Human Papillomavirus Messenger RNA Testing Using Urine, Cervicovaginal Self-Collected and Provider-Collected Cervical Samples Among Women in Mombasa, Kenya

Journal

SEXUALLY TRANSMITTED DISEASES
Volume 49, Issue 11, Pages 782-785

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/OLQ.0000000000001619

Keywords

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Funding

  1. Cancer Control Education Program at UNC Lineberger Comprehensive Cancer Center [T32CA057726-28]
  2. Cancer Care Quality Training Program at UNC Lineberger Comprehensive Cancer Center [2T32CA116339-11]
  3. Center for AIDS Research
  4. National Institutes of Health [P30 AI050410]
  5. National Cancer Institute [U54 CA254564]

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Among females engaged in sex work in Kenya, urine self-collection is considered a comfortable and acceptable method for detecting human papillomavirus. However, detection of high-grade cervical cytology was less likely in urine samples compared to self- and provider-collected cervical samples.
We compared human papillomavirus messenger RNA testing using urine, self-, and provider-collected samples for the detection of high-grade cervical cytology and assessed acceptability of urine self-collection among females who engage in sex work in Kenya. Participants found urine sampling comfortable, but high-risk human papillomavirus messenger RNA detection in urine samples was less likely to detect high-grade lesions than self- and provider-collected cervical samples.

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