Related references
Note: Only part of the references are listed.A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease
G. A. Horne et al.
LEUKEMIA (2020)
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors
Pablo Baquero et al.
LEUKEMIA (2019)
Renal dysfunction and anemia associated with long-term imatinib treatment in patients with chronic myelogenous leukemia
Masatoshi Sakurai et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2019)
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Kirsten L. Bryant et al.
NATURE MEDICINE (2019)
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Conan G. Kinsey et al.
NATURE MEDICINE (2019)
MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival
Chih-Shia Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer A Phase 2 Randomized Clinical Trial
Thomas B. Karasic et al.
JAMA ONCOLOGY (2019)
Targeting Autophagy in Cancer: Recent Advances and Future Directions
Ravi K. Amaravadi et al.
CANCER DISCOVERY (2019)
PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
Vito W. Rebecca et al.
CANCER DISCOVERY (2019)
Cargo recognition and degradation by selective autophagy
Damian Gatica et al.
NATURE CELL BIOLOGY (2018)
Mechanism and medical implications of mammalian autophagy
Ivan Dikic et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress
Katie R. Martin et al.
ISCIENCE (2018)
Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice
Paul H. Miller et al.
EXPERIMENTAL HEMATOLOGY (2017)
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells
Elodie M. Kuntz et al.
NATURE MEDICINE (2017)
The chronic myeloid leukemia stem cell: stemming the tide of persistence
Tessa L. Holyoake et al.
BLOOD (2017)
ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy
Terytty Yang Li et al.
MOLECULAR CELL (2016)
Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy
Katy J. Petherick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Using enhanced-mitophagy to measure autophagic flux
Alice D. Baudot et al.
METHODS (2015)
Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates
Daniel F. Egan et al.
MOLECULAR CELL (2015)
Incidence of persistent/late chronic anemia in newly diagnosed patients with chronic myeloid leukemia responsive to imatinib
Roberto Latagliata et al.
AMERICAN JOURNAL OF HEMATOLOGY (2015)
Do we need more drugs for chronic myeloid leukemia?
Tessa L. Holyoake et al.
IMMUNOLOGICAL REVIEWS (2015)
Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer
Andrew Poklepovic et al.
AUTOPHAGY (2014)
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
William E. Dowdle et al.
NATURE CELL BIOLOGY (2014)
A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy
Baptiste Ronan et al.
NATURE CHEMICAL BIOLOGY (2014)
Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis
Jing Liu et al.
BLOOD (2013)
Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis
Stephen W. G. Tait et al.
CELL REPORTS (2013)
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
Ashley Hamilton et al.
BLOOD (2012)
Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
Margaret Nieborowska-Skorska et al.
BLOOD (2012)
Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia
Bin Zhang et al.
CANCER CELL (2012)
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
Vincent Soubannier et al.
CURRENT BIOLOGY (2012)
The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
Daniel F. Egan et al.
AUTOPHAGY (2011)
Leukemic stem cell persistence in chronic myeloid leukemia patients with sustained undetectable molecular residual disease
Jean-Claude Chomel et al.
BLOOD (2011)
Pancreatic cancers require autophagy for tumor growth
Shenghong Yang et al.
GENES & DEVELOPMENT (2011)
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2011)
Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
Amie S. Corbin et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Hsp90-Cdc37 Chaperone Complex Regulates Ulk1-and Atg13-Mediated Mitophagy
Joung Hyuck Joo et al.
MOLECULAR CELL (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
Effective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate
Bin Zhang et al.
CANCER CELL (2010)
Nix is a selective autophagy receptor for mitochondrial clearance
Ivana Novak et al.
EMBO REPORTS (2010)
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial
Francois-Xavier Mahon et al.
LANCET ONCOLOGY (2010)
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo
M. Mortensen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
Ji Zhang et al.
BLOOD (2009)
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
Cristian Bellodi et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy
Nao Hosokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis
Ke Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
Mondira Kundu et al.
BLOOD (2008)
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
Chong Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae
Heesun Cheong et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Growth factor stimulation reduces residual quiescent chronic myelogenous leukemia progenitors remaining after imatinib treatment
Melissa Holtz et al.
CANCER RESEARCH (2007)
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
K Ito et al.
NATURE MEDICINE (2006)
Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis
S Koschmieder et al.
BLOOD (2005)
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
SG O'Brien et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)