4.7 Review

Drug pollution & Sustainable Development Goals

Related references

Note: Only part of the references are listed.
Review Medical Informatics

Update of EMA's Guideline on the Environmental Risk Assessment (ERA) of Medicinal Products for Human Use

Ralf Arno Wess

Summary: This article addresses the potential harm pharmaceutical residues can cause to the environment and discusses the revised Environmental Risk Assessment guideline by the European Medicines Agency. The introduction of a tailored testing approach for antibiotics, changes in required study types, and adaptations in environmental fate evaluation are highlighted. Recommendations are made to consider ERA earlier in the drug development process to mitigate unnecessary costs and risks.

THERAPEUTIC INNOVATION & REGULATORY SCIENCE (2021)

Article Environmental Sciences

Neuroactive drugs and other pharmaceuticals found in blood plasma of wild European fish

Daniel Cerveny et al.

Summary: Through analyzing the plasma of wild fish from multiple countries, it was found that some pharmaceuticals exceeded 10% of the therapeutic plasma concentration in fish, including drugs that target the central nervous system like flupentixol, haloperidol, and risperidone. This not only highlights pharmaceuticals of environmental concern, but also emphasizes the importance of monitoring internal drug levels in aquatic wildlife.

ENVIRONMENT INTERNATIONAL (2021)

Letter Psychiatry

Venlafaxine and desvenlafaxine to be included in the surface water Watch List

Unax Lertxundi et al.

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2021)

Article Engineering, Environmental

Aquatic Insects Transfer Pharmaceuticals and Endocrine Disruptors from Aquatic to Terrestrial Ecosystems

Ana Previsic et al.

Summary: The study provides evidence of the transfer of pharmaceuticals and endocrine disruptors through the aquatic-terrestrial habitat by emerging aquatic insects. Adult Trichoptera, an important food source for riparian predators, showed increased body burden of these contaminants. The transfer of these contaminants from aquatic primary producers to terrestrial predators may impact their physiology and population dynamics.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2021)

Article Medicine, General & Internal

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19 A Randomized Clinical Trial

Eduardo Lopez-Medina et al.

Summary: The study found that a 5-day course of ivermectin did not significantly improve the time to resolution of symptoms in adults with mild COVID-19, and does not support its use for treatment of mild COVID-19. Larger trials may be needed to understand the effects of ivermectin on other clinically relevant outcomes.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Article Engineering, Environmental

The Role of Behavioral Ecotoxicology in Environmental Protection

Alex T. Ford et al.

Summary: Chemicals have long been acknowledged to impact human and wildlife behavior. Recent technological advancements have highlighted the adverse effects of contaminants on organismal behavior and ecological outcomes. Concerns about the lack of consideration of behavior in regulatory ecotoxicology have led to the exclusion of many studies from chemical risk assessments. A workshop with international representatives has resulted in consensus perspectives and recommendations to improve the integration of basic and translational sciences with regulatory practices.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2021)

Article Environmental Sciences

Environmental contamination by pet pharmaceuticals: A hidden problem

Saioa Domingo-Echaburu et al.

Summary: Companion animal pharmaceuticals are assumed to have low environmental risks, with European Medicines Agency not requiring data on their fate, behavior, or effects. Concerns have been raised about the environmental impacts of indiscriminate use of antiparasitic drugs in pets, and it is suggested that environmental aspects should be incorporated into the benefit-risk assessment of drugs used in companion animals.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

Article Development Studies

Degradation and disease: Ecologically unequal exchanges cultivate emerging pandemics

Kelly F. Austin

Summary: This passage highlights that 75% of new infectious diseases stem from human and animal interactions, with new diseases like COVID-19 often originating from biodiversity hotspots and forest loss intensifying human-animal contact. A political-economy approach reveals how trade inequalities result in environmental and human exploitation in poor nations, creating conditions for pandemics like COVID-19 to arise, and cross-national patterns in deforestation and forest use demonstrate how consumers in the Global North are closely linked to the emergence of zoonotic diseases.

WORLD DEVELOPMENT (2021)

Article Environmental Sciences

Utilisation of waste medicine wrappers as an efficient low-cost electrode material for microbial fuel cell

Md. T. Noori et al.

ENVIRONMENTAL TECHNOLOGY (2020)

Article Public, Environmental & Occupational Health

Presence of pharmaceutical compounds, levels of biochemical biomarkers in seafood tissues and risk assessment for human health: Results from a case study in North-Western Spain

Salome Martinez-Morcillo et al.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2020)

Letter Veterinary Sciences

ENVIRONMENT Environmental pollution from pet parasiticides

Christopher J. L. Little et al.

VETERINARY RECORD (2020)

Article Engineering, Environmental

Green solvents in recovery of aluminium and plastic from waste pharmaceutical blister packaging

Joona Nieminen et al.

WASTE MANAGEMENT (2020)

Article Medicine, General & Internal

Mass drug administration: time to consider drug pollution?

Gorka Orive et al.

LANCET (2020)

Letter Infectious Diseases

COVID-19, antibiotics and One Health: a UK environmental risk assessment

Sean D. W. Comber et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)

Article Environmental Sciences

First record of emerging contaminants in sponges of an inhabited island in the Maldives

Cristiana Rizzi et al.

MARINE POLLUTION BULLETIN (2020)

Review Microbiology

Bat-borne virus diversity, spillover and emergence

Michael Letko et al.

NATURE REVIEWS MICROBIOLOGY (2020)

Article Multidisciplinary Sciences

Biomagnification and body distribution of ivermectin in dung beetles

Jose R. Verdu et al.

SCIENTIFIC REPORTS (2020)

Article Environmental Sciences

Human pharmaceuticals in marine mussels: Evidence of sneaky environmental hazard along Italian coasts

Marica Mezzelani et al.

MARINE ENVIRONMENTAL RESEARCH (2020)

Editorial Material Public, Environmental & Occupational Health

Importance of the One Health approach to study the SARS-CoV-2 in Latin America

D. Katterine Bonilla-Aldana et al.

ONE HEALTH (2020)

Article Psychiatry

Drug pollution and pharmacotherapy in psychiatry: A platypus in the room

Unax Lertxundi et al.

EUROPEAN PSYCHIATRY (2020)

Review Environmental Sciences

Pharmaceuticals in freshwater aquatic environments: A comparison of the African and European challenge

Samuel Fekadu et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Article Environmental Sciences

Persistent and transgenerational effects of risperidone in zebrafish

Fabiana Kalichak et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2019)

Review Virology

Bats and Coronaviruses

Arinjay Banerjee et al.

VIRUSES-BASEL (2019)

Review Environmental Sciences

Antibiotic resistance genes identified in wastewater treatment plant systems - A review

Magdalena Pazda et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Review Environmental Sciences

A review of the pharmaceutical exposome in aquatic fauna

Thomas H. Miller et al.

ENVIRONMENTAL POLLUTION (2018)

Article Environmental Sciences

Sorption, plant uptake and metabolism of benzodiazepines

Laura J. Carter et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2018)

Review Plant Sciences

Novel perspectives on the molecular crosstalk mechanisms of serotonin and melatonin in plants

Soumya Mukherjee

PLANT PHYSIOLOGY AND BIOCHEMISTRY (2018)

Article Multidisciplinary Sciences

Experimental manipulation of monoamine levels alters personality in crickets

Robin N. Abbey-Lee et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

A diverse suite of pharmaceuticals contaminates stream and riparian food webs

Erinn K. Richmond et al.

NATURE COMMUNICATIONS (2018)

Article Gastroenterology & Hepatology

Effects of antipsychotics on intestinal motility in zebrafish larvae

K. A. F. de Alvarenga et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2017)

Article Ecology

Synthetic chemicals as agents of global change

Emily S. Bernhardt et al.

FRONTIERS IN ECOLOGY AND THE ENVIRONMENT (2017)

Article Marine & Freshwater Biology

Statins: An undesirable class of aquatic contaminants?

Miguel M. Santos et al.

AQUATIC TOXICOLOGY (2016)

Review Environmental Sciences

Pharmaceuticals in soils of lower income countries: Physico-chemical fate and risks from wastewater irrigation

Katherine Lees et al.

ENVIRONMENT INTERNATIONAL (2016)

Review Chemistry, Physical

Pharmaceuticals pollution of aquaculture and its management in China

Zhenxiang He et al.

JOURNAL OF MOLECULAR LIQUIDS (2016)

Article Materials Science, Biomaterials

Ginsenoside nanoparticle: a new green drug delivery system

Lin Dai et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

Editorial Material Multidisciplinary Sciences

Time to get clean

[Anonymous]

NATURE (2015)

Article Multidisciplinary Sciences

Global trends in antimicrobial use in food animals

Thomas P. Van Boeckel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters

Sunita A. Ramesh et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Supplanting ecosystem services provided by scavengers raises greenhouse gas emissions

Zebensui Morales-Reyes et al.

SCIENTIFIC REPORTS (2015)

Review Biology

Pollution from drug manufacturing: review and perspectives

D. G. Joakim Larsson

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Sources, impacts and trends of pharmaceuticals in the marine and coastal environment

Sally Gaw et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Editorial Material Biochemistry & Molecular Biology

Plant Neurobiology, a Fascinating Perspective in the Field of Research on Plant Secondary Metabolites

Marcello Iriti

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Review Clinical Neurology

Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models

Adam Stewart et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2011)

Article Environmental Sciences

CHRONIC EXPOSURE TO FLUOXETINE (PROZAC) CAUSES DEVELOPMENTAL DELAYS IN RANA PIPIENS LARVAE

Hannah R. Foster et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2010)

Article Multidisciplinary Sciences

Collapse of a fish population after exposure to a synthetic estrogen

Karen A. Kidd et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Diclofenac residues as the cause of vulture population decline in Pakistan

JL Oaks et al.

NATURE (2004)

Article Medicine, Research & Experimental

Evolutional study on acetylcholine expression

Y Horiuchi et al.

LIFE SCIENCES (2003)

Article Pharmacology & Pharmacy

The biological role of non-neuronal acetylcholine in plants and humans

I Wessler et al.

JAPANESE JOURNAL OF PHARMACOLOGY (2001)