4.7 Review

N-heterocyclic carbene-catalyzed arene formation reactions

Journal

SCIENCE CHINA-CHEMISTRY
Volume 65, Issue 2, Pages 210-223

Publisher

SCIENCE PRESS
DOI: 10.1007/s11426-021-1133-5

Keywords

N-heterocyclic carbene; arene construction; cycloaddition; organocatalysis

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This review discusses N-heterocyclic carbene-catalyzed reactions for the formation of aromatic compounds, categorizing them into 4 types based on activation modes. The achievements, challenges, and future research directions in NHC-catalyzed arene construction processes are summarized. The outlook is based on the authors' opinions and knowledge on the trends of NHC organocatalysis development.
N-heterocyclic carbene-catalyzed reactions for the formation of aromatic compounds are reviewed. The reactions are subdivided into 4 types based on their activation modes. A brief summary on the achievements and the challenges remaining in N-heterocyclic carbene (NHC)-catalyzed arene construction processes is provided at the end of this review. An outlook into the future research direction within this field is also given based on our own opinion and knowledge on the trends of the development of NHC organocatalysis.

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