Visible-light-mediated tungsten-catalyzed C-H amination of unactivated alkanes with nitroarenes

Alkylamines are important motifs in pharmaceutical and material sciences. The existing reports of C-H amination are limited to ammonia, diazo and azide nitrogen sources. This work describes a rapid construction of C-N bonds from accessible nitroarene and alkane feedstock under decatungstate catalysis. A variety of C-H precursors including gaseous, linear, cyclic and benzylic hydrocarbons could adopt this protocol to afford the corresponding alkylamines in high efficiency

Automated summary

This study presents a rapid method for constructing C-N bonds from accessible nitroarene and alkane feedstock using decatungstate catalysis. Various types of C-H precursors can be efficiently converted into the corresponding alkylamines using this protocol.