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Male fertility as a marker for health

Journal

REPRODUCTIVE BIOMEDICINE ONLINE
Volume 44, Issue 1, Pages 131-144

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.rbmo.2021.09.023

Keywords

Andrology; Biomarker; Infertility; Men's health

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Male reproduction is associated with medical diseases, psychological diseases, environmental exposures, dietary habits, and other factors. Diagnosis of male infertility is related to future disease risk. The evaluation of male fertility provides an opportunity to improve male health, requiring a multidisciplinary approach.
Male reproduction is a complex biological process, and male factor infertility is increasingly recognized as a biomarker for overall male health. Emerging data suggest associations between male reproduction and medical disease (genetic, infectious, chronic comorbid conditions), psychological disease, environmental exposures, dietary habits, medications and substances of abuse, and even socioeconomic factors. There is also evidence that a diagnosis of male fertility is associated with future disease risk including cancer, metabolic disease and mortality. As such, there is a growing view that the male fertility evaluation is an opportunity to improve a man's health beyond his immediate reproductive goals, and also highlights the necessity of a multidisciplinary approach.

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