Related references
Note: Only part of the references are listed.Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
Sung-Hoon Kim et al.
MOLECULAR CELL (2021)
The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
Shu Yang et al.
DEVELOPMENTAL CELL (2020)
p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy-lysosomal pathway and coordinate cell cycle and cell growth
Ada Nowosad et al.
NATURE CELL BIOLOGY (2020)
Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
Yao Yao et al.
MOLECULAR CELL (2020)
Molecular Control of Oligodendrocyte Development
Benayahu Elbaz et al.
TRENDS IN NEUROSCIENCES (2019)
Nutrient regulation of mTORC1 at a glance
Kendall J. Condon et al.
JOURNAL OF CELL SCIENCE (2019)
Seh1 targets GATOR2 and Nup153 to mitotic chromosomes
Melpomeni Platani et al.
JOURNAL OF CELL SCIENCE (2018)
Early nutrition influences developmental myelination and cognition in infants and young children
Sean Deoni et al.
NEUROIMAGE (2018)
The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex
Ana M. Meireles et al.
DEVELOPMENTAL CELL (2018)
Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex
Ebru Ercan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway
Rachel L. Wolfson et al.
CELL METABOLISM (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
METABOLISM Sestrin2 is a leucine sensor for the mTORC1 pathway
Rachel L. Wolfson et al.
SCIENCE (2016)
Oligodendrocyte Development and Plasticity
Dwight E. Bergles et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
Lynne Chantranupong et al.
CELL (2016)
Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells
Aaron M. Hosios et al.
DEVELOPMENTAL CELL (2016)
Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
Robert A. Saxton et al.
NATURE (2016)
The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function
Weili Cai et al.
PLOS GENETICS (2016)
Dynamics and Mechanisms of CNS Myelination
Kathryn K. Bercury et al.
DEVELOPMENTAL CELL (2015)
GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2
Jiangbin Ye et al.
GENES & DEVELOPMENT (2015)
Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes
Melpomeni Platani et al.
JOURNAL OF CELL BIOLOGY (2015)
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
Suchithra Menon et al.
CELL (2014)
Regulation of TORC1 in Response to Amino Acid Starvation via Lysosomal Recruitment of TSC2
Constantinos Demetriades et al.
CELL (2014)
Oligodendrocyte Precursor Cell-Intrinsic Effect of Rheb1 Controls Differentiation and Mediates mTORC1-Dependent Myelination in Brain
Yi Zou et al.
JOURNAL OF NEUROSCIENCE (2014)
Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination
Kathryn K. Bercury et al.
JOURNAL OF NEUROSCIENCE (2014)
Mammalian Target of Rapamycin Promotes Oligodendrocyte Differentiation, Initiation and Extent of CNS Myelination
Stacey E. Wahl et al.
JOURNAL OF NEUROSCIENCE (2014)
Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination
Frederic Lebrun-Julien et al.
JOURNAL OF NEUROSCIENCE (2014)
TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila
Youheng Wei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
Lynne Chantranupong et al.
CELL REPORTS (2014)
Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex
Anita Parmigiani et al.
CELL REPORTS (2014)
Myelination and Oligodendrocyte Functions in Psychiatric Diseases
Klaus-Armin Nave et al.
JAMA PSYCHIATRY (2014)
General Control Nonderepressible 2 (GCN2) Kinase Protects Oligodendrocytes and White Matter during Branched-chain Amino Acid Deficiency in Mice
Pengxiang She et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain
Ethan G. Hughes et al.
NATURE NEUROSCIENCE (2013)
A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
Liron Bar-Peled et al.
SCIENCE (2013)
Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway
Jung Min Han et al.
CELL (2012)
Regulation of DNA replication during development
Jared Nordman et al.
DEVELOPMENT (2012)
The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and Autophagy
Eric M. Wauson et al.
MOLECULAR CELL (2012)
Anaplastic Lymphoma Kinase Spares Organ Growth during Nutrient Restriction in Drosophila
Louise Y. Cheng et al.
CELL (2011)
Rheb1 Is Required for mTORC1 and Myelination in Postnatal Brain Development
Jia Zou et al.
DEVELOPMENTAL CELL (2011)
A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole in Saccharomyces cerevisiae
Svetlana Dokudovskaya et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
Roberto Zoncu et al.
SCIENCE (2011)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
Regulation of Tissue Growth through Nutrient Sensing
Ville Hietakangas et al.
ANNUAL REVIEW OF GENETICS (2009)
Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination
S. Priyadarshini Narayanan et al.
JOURNAL OF NEUROSCIENCE (2009)
Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression
Christine Stritt et al.
NATURE NEUROSCIENCE (2009)
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
Ulrich Schueller et al.
CANCER CELL (2008)
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
Leanne E. Rivers et al.
NATURE NEUROSCIENCE (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
White matter in learning, cognition and psychiatric disorders
R. Douglas Fields
TRENDS IN NEUROSCIENCES (2008)
A mouse model of tuberous sclerosis: Neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
Lynsey Meikle et al.
JOURNAL OF NEUROSCIENCE (2007)
Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways
DJ Kwiatkowski et al.
HUMAN MOLECULAR GENETICS (2005)
Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression
CJ Nelsen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A CamKIIα iCre BAC allows brain-specific gene inactivation
E Casanova et al.
GENESIS (2001)
The oligodendrocyte precursor cell in health and disease
JM Levine et al.
TRENDS IN NEUROSCIENCES (2001)