4.8 Article

Sequence locally, think globally: The Darwin Tree of Life Project

Publisher

NATL ACAD SCIENCES
DOI: 10.1073/pnas.2115642118

Keywords

genome; sequencing; biodiversity; assembly

Funding

  1. Wellcome Trust [218328]
  2. Sanger Institute [206194]

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The Earth Biogenome Project aims to sequence the genomes of all eukaryotic life on earth, and the Darwin Tree of Life Project focuses on delivering high-quality genome sequences for the British and Irish islands. The collaboration between biodiversity organizations and genomics institutes has established a workflow that collects specimens, performs sequencing, generates curated assemblies, and openly releases the data for global use in future scientific and conservation efforts.
The goals of the Earth Biogenome Project-to sequence the genomes of all eukaryotic life on earth-are as daunting as they are ambitious. The Darwin Tree of Life Project was founded to demonstrate the credibility of these goals and to deliver at-scale genome sequences of unprecedented quality for a biogeographic region: the archipelago of islands that constitute Britain and Ireland. The Darwin Tree of Life Project is a collaboration between biodiversity organizations (museums, botanical gardens, and biodiversity institutes) and genomics institutes. Together, we have built a workflow that collects specimens from the field, robustly identifies them, performs sequencing, generates high-quality, curated assemblies, and releases these openly for the global community to use to build future science and conservation efforts.

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