Journal
POLYMER INTERNATIONAL
Volume 71, Issue 5, Pages 578-582Publisher
WILEY
DOI: 10.1002/pi.6358
Keywords
polydopamine; surface coatings; biomaterials; medical applications
Categories
Funding
- National Science Foundation EPSCoR Program under NSF Award [OIA-1655740]
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Polydopamine is a simple and versatile biopolymer that is being extensively studied as a surface modifying agent due to its ease of preparation and biocompatibility. Its resemblance to key components of mussel adhesive proteins has led to its incorporation into composite materials. This review focuses on the emerging investigations into the mechanism, structures, and potential applications of polydopamine, with a particular emphasis on its use in biomedicine.
Polydopamine is a biopolymer that is gaining widespread interest as a surface modifying agent due to its simplicity of preparation, versatility and biocompatibility. The material was first described during electrochemical studies of dopamine, but recognition of its structural similarity to key components of mussel adhesive proteins, which are able to adhere to a diverse range of surfaces in water, has led to its incorporation into a host of composite materials. This review will examine some of the emerging investigations into the complex mechanism of polydopamine formation, proposed structures and potential applications, with an emphasis on its use in biomedicine. (c) 2021 Society of Industrial Chemistry.
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